47 citations
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August 2016 in “American Journal Of Pathology” This study reports that in systemic sclerosis, CD34+ dermal fibroblasts transition to CD34−, podoplanin+, and CD90+ fibroblasts across the dermis, suggesting a role in unchecked fibrosis.
14 citations
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January 2019 in “Journal of Natural Medicines” This study found that certain compounds from Chaga mushrooms stimulated the proliferation of human hair follicle cells more effectively than minoxidil, suggesting potential for hair-growth treatments.
September 2025 in “Arthritis Research & Therapy” In this study, researchers found that the compound BMS-470539 induced a senescence-like state in fibroblasts from systemic sclerosis patients, reducing fibrosis-associated markers in vitro and decreasing skin thickness in a mouse model of skin fibrosis, suggesting a novel therapeutic strategy for managing fibroblast-driven diseases.
3 citations
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September 2024 in “The FASEB Journal” This review discusses the roles of dermal white adipose tissue in skin functions and pathology, underscoring its antibacterial activity and potential anti-fibrotic role, but reports no new experimental results.
This pilot study found that a high fat lard diet may protect against fibrosis and affect the hair follicle cycle in a mouse model of systemic sclerosis, unlike a high fat coconut oil diet.