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research Tetrathiomolybdate Decreases the Expression of Alkaline Phosphatase in Dermal Papilla Cells by Increasing Mitochondrial ROS Production

2 citations , February 2023 in “International journal of molecular sciences”

This study identified that copper depletion in dermal papilla cells reduced hair growth by boosting ROS levels, but ROS scavengers like NAC and ascorbic acid partially alleviated this effect.

research Hair follicles’ transit-amplifying cells govern concurrent dermal adipocyte production through Sonic Hedgehog

75 citations , October 2016 in “Genes & Development”

This study found that Sonic Hedgehog secreted by hair follicle transit-amplifying cells is essential for dermal adipogenesis and hair follicle growth by acting on adipocyte precursors.

Scalable Production of Controllable Dermal Papilla Spheroids on PVA Surfaces and the Effects of Spheroid Size on Hair Follicle Regeneration

research Scalable production of controllable dermal papilla spheroids on PVA surfaces and the effects of spheroid size on hair follicle regeneration

78 citations , October 2012 in “Biomaterials”

This study found that both human and rat dermal papilla spheroids can induce hair follicle neogenesis, but larger spheroids increase inductivity without significantly affecting hair fiber diameter.

research Controllable Production of Transplantable Adult Human High-Passage Dermal Papilla Spheroids Using 3D Matrigel Culture

46 citations , September 2014 in “Tissue engineering. Part A”

This study found that a 3D Matrigel culture technique for dermal papilla cell spheroids can enhance hair follicle inductivity and induce hair-like fiber differentiation in vitro, even with high-passage cells.

research De Novo Production of Dermal Papilla Cells during the Anagen Phase of the Hair Cycle

41 citations , June 2010 in “Journal of Investigative Dermatology”

This study suggests that new cells are incorporated into the dermal papilla during the early anagen phase of the hair cycle, which may influence hair growth consistency and follicle size changes.

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community Dermastamping — do you use hyaluronic acid as lubricant?

3 upvotes 1 year ago

The conversation discusses using high molecular weight hyaluronic acid after microneedling to form a protective barrier, though it's considered expensive and offers marginal improvement. Users share experiences with different microneedling tools like derma rollers, dermastamps, and Dr. Pen, with some opting not to use any products on the scalp.

community Need advice, seeing growth by using just a derma roller

10 upvotes 6 years ago

User reports using a derma roller daily, seeing new hair growth along the hairline without using Minoxidil or finasteride. They seek advice on further promoting hair growth with their current routine.

community [Nov 2019] The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression

23 upvotes 6 years ago

A peptide from Japanese water chestnut fruit may help with hair loss by suppressing DHT's effect on hair follicle cell death, potentially serving as a finasteride alternative. The treatment's effectiveness and safety in humans remain uncertain.

community 26, seeing some incredible results 3,5 months in with topical minoxidil and derma rolling 1x a week

in Progress Pictures 265 upvotes 1 year ago

A user experienced significant hair regrowth after 3.5 months using topical minoxidil and weekly derma rolling. Others discussed enhancing results with finasteride, ketoconazole shampoo, and microneedling.