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research Luteinizing Hormone and Human Chorionic Gonadotropin Decrease Type 2 5α-Reductase and Androgen Receptor Protein Levels in Women’s Skin

13 citations , May 1998 in “The Journal of Clinical Endocrinology & Metabolism”

This study found that hCG decreased 5α-reductase and androgen receptor levels in skin samples from women in vitro, suggesting that human skin responds to LH/hCG treatment.

research The injectable contraceptives depot medroxyprogesterone acetate and norethisterone enanthate substantially and differentially decrease testosterone and sex hormone binding globulin levels: A secondary study from the WHICH randomized clinical trial

4 citations , August 2024 in “PLoS ONE”

In this study, researchers reported that both progestin-only injectable contraceptives, DMPA-IM and NET-EN, significantly decreased serum testosterone and SHBG levels among HIV-negative women in South Africa, yet this did not explain prior findings of no reduction in risky sexual behavior or sexual function.

research 5α-Reductase type 2 gene variant associations with prostate cancer risk, circulating hormone levels and androgenetic alopecia

57 citations , November 2006 in “International Journal of Cancer”

This study found that the SRD5A2 A49T A variant is associated with an increased risk of prostate cancer, lower circulating 3α‐diolG levels, and a decreased risk of baldness.

research Serum Levels of Androgen-Associated Hormones Are Correlated with Curative Effect in Androgenic Alopecia in Young Men

9 citations , October 2018 in “Medical Science Monitor”

In this study, oral finasteride therapy was associated with decreased DHT levels and improved hair loss severity in young male AGA patients, while hormonal changes influenced the curative effect.

research The effect of laparoscopic ovarian drilling on the serum levels of AMH, FSH, LH and Testosterone hormones, in patients with PCOS

June 2019 in “The Medical journal of Basrah University”

This study found that laparoscopic ovarian drilling effectively decreased LH and testosterone levels, aiding fertility in PCOS patients nonresponsive to certain medications, without negatively impacting ovarian reserve.

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Community Join

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community Are these safe levels to start taking Finasteride (M, 25)?

8 upvotes 3 years ago

The conversation discusses concerns about starting finasteride with low testosterone levels, with one person suggesting finasteride might increase testosterone and decrease DHT, and another advising to pay attention to thyroid-stimulating hormone (TSH) levels.

community A lot of blood tests that I have done until now (Mainly Hormones).

4 upvotes 5 years ago

The user shared their experience with hair loss treatments, including oral and topical Finasteride and Minoxidil, and detailed various blood test results to track hormonal changes. They noted that while DHT levels initially decreased with topical Finasteride, they later increased, but they observed positive results in hair growth.

community Thought I should share progression of my hormone levels over time

in Finasteride/Dutasteride 1 upvotes 1 year ago

The user shared their hormone levels over time while using finasteride and dutasteride for hair loss. They experienced a significant drop in DHT levels but continued to lose hair, hoping for better results in the future.

community 23M Wierd blood test results after 7 months on finasteroid (1mg daily)

5 upvotes 8 months ago

A user experienced unexpected hormone test results after 7 months on 1mg daily finasteride, noting a decrease in estradiol despite expectations of an increase. Other users suggested that hormone responses can vary and that finasteride might still be effective if DHT levels are within range, while also mentioning factors like circadian rhythm and stress that could impact results.

community Dutasteride Hormone Roller Coaster - Testosterone down, then up, then level, then estrogen up

4 upvotes 3 years ago

Dutasteride effectively stops hair loss but can cause side effects like sexual dysfunction, muscle mass changes, and testicle shrinkage. Adjusting the dosage may help manage these side effects, but long-term health effects remain a concern.

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Learn

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learn Dutasteride

Heavy duty finasteride that comes with higher risks

learn Overview

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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