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Three-Month Treatment With a Long-Acting Gonadotropin-Releasing Hormone Agonist of Patients With Benign Prostatic Hyperplasia: Effects on Tissue Androgen Concentration, 5α-Reductase Activity and Androgen Receptor Content

research Three-Month Treatment With a Long-Acting Gonadotropin-Releasing Hormone Agonist of Patients With Benign Prostatic Hyperplasia: Effects on Tissue Androgen Concentration, 5α-Reductase Activity and Androgen Receptor Content

82 citations, February 1989 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

research Androgens Protect Against Apolipoprotein E4-Induced Cognitive Deficits

182 citations, June 2002 in “Journal of Neuroscience”

Androgens can help prevent memory problems caused by apoE4.

Synthesis and Structure–Activity Studies of Side-Chain Derivatized Arylhydantoins for Investigation as Androgen Receptor Radioligands

research Synthesis and Structure–Activity Studies of Side-Chain Derivatized Arylhydantoins for Investigation as Androgen Receptor Radioligands

18 citations, April 2001 in “Bioorganic & Medicinal Chemistry Letters”

The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.

Synthesis and Structure–Activity Investigation of Iodinated Arylhydantoins and Arylthiohydantoins for Development as Androgen Receptor Radioligands

research Synthesis and Structure–Activity Investigation of Iodinated Arylhydantoins and Arylthiohydantoins for Development as Androgen Receptor Radioligands

6 citations, November 2004 in “Bioorganic & Medicinal Chemistry Letters”

Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.

research Androgen Receptor Polymorphism-Dependent Variation in Prostate-Specific Antigen Concentrations of European Men

9 citations, September 2014 in “Cancer Epidemiology, Biomarkers & Prevention”

Certain genetic variants in the androgen receptor are linked to higher PSA levels, potentially affecting prostate cancer screening outcomes.

View more "cytosolic ar" in research →

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community If you’re sitting there wondering, “I’m losing my hair, what do I do?” then read my advice here. I’ve been fighting the fight for 7 years, with great success. (pictures included)

in Question 106 upvotes 11 years ago

Fighting hair loss with "The Big 3" treatments of Propecia, Rogaine and Nizoral shampoo, as well as specific advice on how to use these products. People have shared their long-term success stories and some have discussed the side effects of finasteride. Other suggestions included Lipogaine and Pura D'or Hair Loss Prevention Therapy Shampoo & Conditioner.

community A meta analysis of 18 popular hair loss treatments. An 2022 guide on efficacy. From finasteride and minoxidil to caffeine shampoo, saw palmetto and biotin. 96 Scientific References included.

in Research/Science 101 upvotes 2 years ago

Most hair loss treatments are ineffective; only finasteride, dutasteride, and minoxidil show effectiveness.

community Alfatradiol to combat hair loss

7 upvotes 10 years ago

Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. Alfatradiol is suggested as another potential solution.

community Switched from finasteride to dutasteride - 2 month update

in Finasteride/Dutasteride 6 upvotes 1 year ago

The user switched from finasteride to dutasteride for hair loss treatment, but experienced increased libido, itchy scalp, and accelerated hair loss. Another user suggested that genetic variations might cause dutasteride to be less effective and recommended checking for specific genetic markers.

community I started rapidly diffuse thinning at 22. I'm 42 now and have as much hair as I did at 16. AMA

in Treatment 445 upvotes 4 years ago

Hair loss treatments like finasteride, minoxidil, ketoconazole, PRP, and microneedling helped maintain hair for 20 years. Research and try evidence-based treatments for best results.