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    Glossary CYP11A1

    enzyme converting cholesterol to pregnenolone, initiating steroid hormone production

    CYP11A1, also known as Cytochrome P450 Family 11 Subfamily A Member 1 or P450scc, is an enzyme crucial for the production of steroid hormones. It catalyzes the conversion of cholesterol to pregnenolone, the first step in the biosynthesis of all steroid hormones, which are vital for various bodily functions including stress response, immune function, and regulation of inflammation.

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    Research 10 of 573

    1. The Associations of Androgen-Related Genes CYP21A2 and CYP19A1 with Severe Acne Vulgaris in Patients from Southwest China Clinical Cosmetic and Investigational Dermatology · 2021 · 10 citations
    2. Genotyping of the rs1800440 Polymorphism in CYP1B1 Gene and the rs9258883 Polymorphism in HLA-B Gene in a Spanish Cohort of 223 Patients with Frontal Fibrosing Alopecia Acta dermato-venereologica · 2023 · 1 citations
    3. Intratumoral <i>De Novo</i> Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors Cancer research · 2011 · 402 citations
    4. The significance of CYP11A1 expression in skin physiology and pathology Molecular and Cellular Endocrinology · 2021 · 91 citations
    5. Investigation of variants of the aromatase gene (CYP19A1) in female pattern hair loss British Journal of Dermatology · 2011 · 15 citations
    6. Association of Single Nucleotide Polymorphisms in the CYP19A1 Gene with Female Pattern Hair Loss in a Chinese Population Dermatology · 2015 · 7 citations
    7. Effect of a Benign Prostatic Hyperplasia (BPH) Xenobiotic - Croton membranaceus Müll.Arg. Root Extract on CYP1A2, CYP3A4, CYP2D6, and GSTM1 Drug Metabolizing Enzymes in Rat Model 2020 · 1 citations
    8. MitoQ upregulates CYP19A1 to protect dermal papilla cells from DHT-induced mitochondrial dysfunction and apoptosis in androgenetic alopecia Biochemical Pharmacology · 2026
    9. Coconut oil works as a gonadal feedback testosterone booster and increases pituitary aromatase (cyp19a1b) expression levels in fugu (Takifugu rubripes) Aquaculture · 2025
    10. Exploring the role of CYP19A1 single nucleotide polymorphisms in the pathogenesis of female pattern hair loss Egyptian Journal of Dermatology and Venerology · 2025
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