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GlossarySkin Homeostasis (cutaneous homeostasis)

balanced state where skin maintains structure and function

Skin homeostasis, also known as cutaneous homeostasis, refers to the balanced state of the skin where it maintains its structure, function, and appearance despite external and internal stressors. This involves a complex interplay of cellular processes, including cell regeneration, immune responses, and barrier function, ensuring the skin remains healthy and capable of protecting the body from environmental threats.

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research Hair, Cutaneous Homeostasis, and Stem Cell Functions

January 2014 in “Journal of Investigative Dermatology”

Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.

research Targeting Cutaneous Cannabinoid Signaling in Inflammation: A Highway to Heal?

28 citations, January 2017 in “EBioMedicine”

Enhancing cannabinoid signaling may help treat skin inflammation.

research Generation of the Krt24-CreERT2 Mouse Line Targeting Outer Bulge Hair Follicle Cells

March 2025 in “International Journal of Molecular Sciences”

The study created a mouse model to better understand hair follicle stem cells' role in hair growth and repair.

research The Biology of Melanocytes

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

Melanocytes are cells that make skin and hair color and help protect skin from sun damage.

research Multiple Roles of Integrin-Linked Kinase in Epidermal Development, Maturation, and Pigmentation Revealed by Molecular Profiling

9 citations, May 2012 in “PLOS ONE”

ILK is essential for skin development, pigmentation, and healing.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community How do you use rosemary oil and peppermint oil?

in Question 6 upvotes 5 years ago

Rosemary oil and peppermint oil may promote hair growth and increase cutaneous blood flow, showing promise as treatments for androgenetic alopecia. Minoxidil 2% is also used for treating hair loss.

community Scientific evidence for Peppermint & Rosemary oils + My Experience

in Research/Science 114 upvotes 2 years ago

Natural treatments for hair loss, specifically peppermint oil and rosemary oil; how they can be used as a supplementary or alternative treatment to pharmaceuticals such as finasteride and minoxidil; and the personal experience of the user Divallo, who has seen an increase in density and thickness after using these oils for around 2.5 years. The post also touches on the potential antifungal properties of the oils and their effects on cutaneous blood flow.

community high bloodpressure and crown thinning in early 20s

in Is this regrowth? 9 upvotes 10 months ago

A user with kidney disease and high blood pressure experienced hair thinning, especially around the vertex. They are currently using finasteride and oral minoxidil but are considering whether to resume blood pressure medication despite managing symptoms with diet and exercise.

community HMI-115 update: Chime Biologics and Hope Medicine Enter Manufacturing Agreement to Speed up the Launch of First-in-class Antibody Drug HMI-115 Targeting Endometriosis and Androgenic Alopecia

in Research/Science 112 upvotes 1 year ago

Chime Biologics and Hope Medicine are speeding up the launch of a first-in-class antibody drug, HMI-115, for endometriosis and androgenic alopecia. The treatment involves a series of subcutaneous injections, has shown promising results in phase 1, and continues to promote hair regrowth even after the treatment is stopped.

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