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research Cultured human and rat tooth papilla cells induce hair follicle regeneration and fiber growth

48 citations , December 2004 in “Differentiation”

This study found that cultured dental papilla cells from various mammals can induce hair follicle regeneration and influence tissue formation, with outcomes dependent on donor age, tooth type, and host environment.

research The patch assay reconstitutes mature hair follicles by culture-expanded human cells

11 citations , July 2017 in “Regenerative Medicine”

This study found that the patch assay effectively reconstituted mature hair follicles using culture-expanded human fetal cells and may serve as a method to assess cell trichogenicity.

research Culture and Differentiation of Human Hair Follicle Dermal Papilla Cells in a Soft 3D Self-Assembling Peptide Scaffold

29 citations , April 2020 in “Biomolecules”

The study suggests that a 3D culture system using the RAD16-I peptide scaffold can help restore the original phenotype of hair follicle dermal papilla cells and support their osteogenic and adipogenic differentiation.

research Human follicular stem cells: their presence in plucked hair and follicular cell culture

82 citations , May 2004 in “British Journal of Dermatology”

This study found CK19/Bcl-2-positive and Bax-negative cells in hair follicle cultures from plucked hairs, supporting their potential identification as follicular stem cells located in the bulge area.

Microenvironmental Reprogramming by Three-Dimensional Culture Enables Dermal Papilla Cells to Induce De Novo Human Hair-Follicle Growth

research Microenvironmental reprogramming by three-dimensional culture enables dermal papilla cells to induce de novo human hair-follicle growth

256 citations , October 2013 in “Proceedings of the National Academy of Sciences of the United States of America”

This study found that altering cell culture conditions to form three-dimensional papilla spheroids can restore the ability of human dermal papilla cells to induce hair growth in adult skin.

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Community Join

5 / 127 results

community New study: Vitamin D counteracts DHT in mice and in human hair organ culture and hair cells

126 upvotes 1 year ago

Vitamin D may counteract DHT and help with hair growth, as seen in mice and human hair cultures. Some users discuss using Vitamin D, magnesium, and other supplements for hair health, while others humorously note the success in mice.

community Baldness Breakthrough: microRNA Stimulates Hair Growth in Aging Follicles

316 upvotes 3 years ago

miR-205, a tiny RNA, can stimulate hair growth by softening aging hair follicle stem cells in mice. Future tests aim to see if this can work in humans.

community Why did this recent research paper from professor Tsuji lab in Japan largely go unnoticed by this sub? Isn't this discovery huge? (hair cloning)

35 upvotes 4 months ago

A recent discovery in hair cloning identified a previously unknown cell type essential for hair follicle growth, which could potentially make lab-grown hair viable if translated to humans. However, skepticism remains due to past delays and the challenges of replicating results in humans and making the process affordable.

community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

14 upvotes 2 years ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 1 year ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

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Learn

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learn Stem Cell Factor

learn Ecklonia Cava

Can Ecklonia Cava be used as a preventive treatment for early signs of hair thinning? No human trial has tested Ecklonia cava for hair loss, so it cannot be called preventive; the evidence is mouse studies and cell cultures suggesting antioxidant activity and 5-alpha-reductase inhibition in the lab.

learn Centella

Got small bald circles with no warning? Centella creams might calm the area and kickstart new growth. There is no published human trial of Centella asiatica for alopecia areata or any other hair loss; the only hair-related studies are cell-culture work. Community users describe Centella creams as soothing for an irritated scalp, not as regrowth treatments, and a new bald patch needs a doctor's diagnosis first.

learn white tea

Is white tea more effective in topical hair products or as an oral supplement for hair growth? Neither topical nor oral white tea has any human clinical trial behind it for hair growth. Topical use has a more direct mechanistic rationale, but the only verifiable studies are a cell-culture EGCG experiment and a pharmacokinetic study with no hair outcomes.

learn KY19382

How is KY19382 applied—topically or orally—for hair growth treatment? In every published study KY19382 has been applied topically, never taken orally; the work is preclinical (cells, cultured follicles and mice) and no human trial results have been published.

learn GHK-Cu

What is GHK-Cu and why is it said to be a "miracle" for hair? GHK-Cu is a copper peptide studied mainly for wound healing and skin repair; for hair loss the evidence stops at cell-culture and animal work, and no published human trial has tested it for androgenetic alopecia.

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Thymosin Beta 4

learn sh-Polypeptide-7

learn Epidermal Growth Factor

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