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The Okuda Papers: An Extraordinary But Unfortunately Unrecognized Piece of Work That Could Have Changed the History of Hair Transplantation

research The Okuda Papers: An Extraordinary But Unfortunately Unrecognized Piece of Work That Could Have Changed the History of Hair Transplantation

8 citations, January 2015 in “Experimental Dermatology”

Dr. Shoji Okuda's pioneering work on hair transplantation was overlooked and could have significantly advanced the field if recognized sooner.

research Hair Restoration in Androgenetic Alopecia: Looking Beyond Minoxidil, Finasteride, and Hair Transplantation

13 citations, January 2016 in “Journal of cosmetology & trichology”

Alternative treatments show promise for hair growth beyond traditional methods.

research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models

38 citations, June 2018 in “Archives of Toxicology”

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The Dermal Papilla: An Instructive Niche for Epithelial Stem and Progenitor Cells in Development and Regeneration of the Hair Follicle

research The Dermal Papilla: An Instructive Niche for Epithelial Stem and Progenitor Cells in Development and Regeneration of the Hair Follicle

149 citations, July 2014 in “Cold Spring Harbor Perspectives in Medicine”

The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.

research Human Hair Keratin Hydrogel: Fabrication, Characterization, and Application

January 2014

Keratin hydrogels from human hair show promise for tissue engineering and regenerative medicine.

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community Is there a topical androgen receptor blocker so we don't have to fuck with the enzyme and destroy our allopregnanolone, but go and hit the end target straight?

in Treatment 47 upvotes 7 months ago

The conversation discusses topical androgen receptor blockers for hair loss, mentioning Clascoterone, Pyrilutamide, GT20029, and RU58841. Ketoconazole's effectiveness and application methods are also debated.

community Can’t do finasteride. Does this automatically cross out Pyrilutamide?

in Research/Science 3 upvotes 1 year ago

Hair loss discussion includes finasteride intolerance and questioning if Pyrilutamide is an alternative. Pyrilutamide not commercially available, but may be tolerable if approved since it's not a 5aR inhibitor.

community How come Dut doesn’t cause more brain problems than fin if it inhibits Type 1 5AR?

in Finasteride/Dutasteride 22 upvotes 5 months ago

Dutasteride and finasteride have similar risk profiles despite Dutasteride blocking more types of 5AR in the brain. Some users report no mood issues with either drug, and it is suggested that Dutasteride's larger molecular size may limit its ability to cross the blood-brain barrier.

community People who tolerate dut better than fin?

in Finasteride/Dutasteride 32 upvotes 2 months ago

Dutasteride may have fewer side effects than finasteride, with some users experiencing better hair maintenance. Experiences vary, with some preferring dutasteride for fewer side effects, while others see no significant hair improvement.

community Has anyone had issues on finasteride that resolved after switching to dutasteride?

in Chat 12 upvotes 1 year ago

Hair loss discussion includes finasteride issues resolved by switching to dutasteride. Specific treatments mentioned: Minoxidil, Finasteride, and RU58841.

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