5 citations
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December 2018 in “Biological & Pharmaceutical Bulletin” In this study, norgalanthamine was found to stimulate hair growth in cultured rat dermal papilla cells by activating the ERK 1/2, PI3K/AKT, and Wnt/β-catenin signaling pathways.
This study suggests that Crinum asiaticum var. japonicum extract and its component norgalanthamine may promote hair growth by inhibiting 5α-reductase activity and the TGF-β1-induced pathway.
12 citations
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January 2010 in “European Journal of Dermatology” In this study, an ethanol extract of Crinum asiaticum was observed to significantly increase hair-fiber lengths and promote hair growth in rat vibrissa follicles and C57BL/6 mice.
41 citations
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July 2015 in “Current Drug Discovery Technologies” This review discusses various plants and herbal formulations traditionally used for hair growth and notes their potential as safer alternatives to synthetic hair loss treatments, but reports no new clinical results.
January 2020 in “Elsevier eBooks” This chapter provides an overview of phytochemicals with properties to combat alopecia and discusses the potential of flavonoids, found in several herbs, as a safer alternative to synthetic hair loss treatments due to their long-term skin compatibility.