501 citations
,
October 2008 in “Psychoneuroendocrinology” This study suggests that cortisol measured in human hair can effectively reflect increased production for up to six months, but its retrospective accuracy may be limited due to rapid decline in levels.
237 citations
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September 2018 in “Clinical Biochemistry” Hair cortisol analysis can help diagnose stress-related conditions but needs more refinement for widespread use.
81 citations
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July 2008 in “The Journal of Clinical Endocrinology and Metabolism” This study found that cortisone reductase deficiency is caused by inactivating mutations in the H6PD gene, affecting cortisol metabolism by preventing 11β-HSD1 enzyme function.
70 citations
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March 2010 in “The Journal of Steroid Biochemistry and Molecular Biology” This study discusses the potential of targeting 11β-HSD1 for treating metabolic syndrome and highlights emerging promising data from human trials on selective 11β-HSD1 inhibitors.
50 citations
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July 2018 in “Psychoneuroendocrinology” In this study, researchers found that tritiated cortisol was incorporated into the hair of rhesus monkeys primarily as cortisol and cortisone, as well as other metabolites, after systemic administration.