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Ectodermal Organ Stem Cells: Morphogenesis, Population Regenerative Behavior, and Evolutionary Development

research Ectodermal Organ Stem Cells: Morphogenesis, Population Regenerative Behavior, and Evo-Devo

1 citations , October 2013

This chapter discusses stem cell activity in feather and hair follicles, emphasizing how stem cells maintain their population by cycling between quiescence and activation in specialized niches but reports no new results.

Quorum Sensing and Other Collective Regenerative Behaviors in Organ Populations

research Quorum sensing and other collective regenerative behavior in organ populations

12 citations , August 2016 in “Current opinion in genetics & development”

In this study, researchers using the hair paradigm highlighted how periodic patterning and compartmentalization enable diverse regenerative behaviors, including region-specific renewal cycles and emergent properties like regenerative waves in organ populations.

research 1378 Identification of two distinct stem cell clusters, Lrig1-derived and Wnt/CD44-dependent, in corneal epithelium

April 2018 in “Journal of Investigative Dermatology”

This study suggests that with aging, mouse corneal renewal increasingly relies on Lrig1+ stem cells as CD44 expression and Wnt activity decline.

research Gab1 and Mapk Signaling Are Essential in the Hair Cycle and Hair Follicle Stem Cell Quiescence

36 citations , October 2015 in “Cell reports”

In this study, researchers found that Gab1 is critical in controlling the hair cycle and the self-renewal of hair follicle stem cells in mice.

research The Progress of Epidermal Stem Cell Research

January 2010

This article reviews the current understanding of the localization, characteristics, and potential markers of epidermal stem cells, and reports no new experimental results.

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community Dutasteride takes 1-3 months to work in the scalp. Not weeks. Be careful.

in Finasteride/Dutasteride 41 upvotes 2 years ago

Dutasteride takes 1-3 months to affect scalp DHT levels, not just a week. The prostate absorbs Dutasteride faster than the scalp due to different vascular networks and enzyme densities.

community Continuous nizoral 1% shampoo use?

in Product 13 upvotes 9 months ago

Nizoral 1% shampoo can be used continuously for hair loss, but it may cause dryness, which can be managed with conditioners. Some users combine it with other treatments like minoxidil and AHK-Cu for better results.

community Shedding continues on 6 months fin

in Finasteride/Dutasteride 5 upvotes 7 months ago

A 35-year-old is experiencing continued hair shedding despite using Finasteride, 2% Ketoconazole shampoo, and dermarolling. They plan to ask their doctor about adding oral Minoxidil and possibly switching to Dutasteride.

community Hair loss continues after 1mg fin daily

in Finasteride/Dutasteride 6 upvotes 4 years ago

The user has been using finasteride 1mg daily, minoxidil once daily, and various oils but continues to experience hair loss. They are considering whether to increase the finasteride dosage or maintain the current regimen until a hair transplant.

community Please help! Continuously thinning while on Fin 1 mg

in Finasteride/Dutasteride 7 upvotes 7 months ago

The user is experiencing continued hair thinning despite taking Finasteride 1 mg daily for over a year and is hesitant to try Minoxidil due to potential side effects and inconsistency. Suggestions include trying topical Minoxidil once a day, considering oral Minoxidil, and possibly getting a skin biopsy to determine the type of hair loss.

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