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GlossaryConfocal Microscopy

uses laser light to create detailed, three-dimensional images

Confocal Microscopy, also known as Confocal Laser Scanning Microscopy (CLSM), is an advanced imaging technique that uses laser light to scan samples and create high-resolution, three-dimensional images. By focusing on a specific plane within the sample and excluding out-of-focus light, it provides clearer and more detailed images than traditional microscopy, making it particularly useful for studying complex structures like hair follicles and skin tissues in both research and medical diagnostics.

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research Abstract 151

April 2015 in “Plastic and Reconstructive Surgery”

Activating TLR3 helps improve skin and hair follicle regeneration after wounds.

research Follicular Transport Route: Research Progress and Future Perspectives

211 citations, February 2009 in “European journal of pharmaceutics and biopharmaceutics”

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

research Confocal Laser Scanning Microscopy as a Tool for the Investigation of Skin Drug Delivery Systems and Diagnosis of Skin Disorders

4 citations, March 2013 in “InTech eBooks”

Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.

research Characterization and Quantification of Wound-Induced Hair Follicle Neogenesis Using In Vivo Confocal Scanning Laser Microscopy

26 citations, April 2011 in “Skin Research and Technology”

In vivo confocal scanning laser microscopy is an effective, non-invasive way to study and measure new hair growth after skin injury in mice.

research In Vivo Reflectance Confocal Microscopy: Usefulness for Diagnosing Hair Diseases

25 citations, December 2008 in “Journal of Dermatological Case Reports”

In vivo reflectance confocal microscopy is useful for evaluating hair shaft diseases but needs improvement for deeper hair follicle issues.

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community Verteporfin and Microneedling

in Treatments 8 months ago

Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.