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Glossary Vasoconstrictors

substances that narrow blood vessels, reducing blood flow

Vasoconstrictors are substances that cause blood vessels to narrow, reducing blood flow and increasing blood pressure. They can be naturally occurring in the body, like adrenaline, or used in medications to treat conditions such as low blood pressure or to reduce blood flow during surgery.

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community Does nicotine have an effect on hair despite using finasteride?

in Research/Science 11 upvotes 5 months ago

Nicotine may negatively affect hair by reducing blood flow due to its vasoconstrictor properties, but its impact might be minimal. Finasteride users are advised to avoid nicotine to prevent potential hair loss issues.

community Could coffee contribute to hair loss?

4 upvotes 4 years ago

Coffee may negatively impact hair health due to its vasoconstrictor effects, potential to increase DHT, and interference with nutrient absorption. There is no strong clinical evidence linking caffeine to hair loss or regrowth in humans, but moderation is advised.

community 2 years of dut, 1 year of loss 24m

515 upvotes 6 months ago

The user experienced hair regrowth with dutasteride but later lost progress despite using minoxidil foam and dermastamping. Suggestions included reducing dermastamping frequency, conducting blood tests, and considering oral minoxidil or different brands of dutasteride.

community 13 months TOPICAL ONLY progress! (Diffuse thinner)

554 upvotes 9 months ago

The conversation is about a user's progress in treating diffuse hair thinning using a topical regimen including finasteride, minoxidil, ketoconazole, microneedling, saw palmetto, collagen, and vitamins, along with lifestyle changes. The user plans to switch from topical to oral finasteride for potentially better results.

community What the hell does caffeine do with hair loss?

2 upvotes 4 years ago

community People who continue to lose hair on fin/dut, Are you on Nicotine?

in Research/Science 81 upvotes 1 year ago

Nicotine use, especially from vaping, may worsen hair shedding and reduce the effectiveness of finasteride and dutasteride. Quitting nicotine seems to improve hair health.

community Forgotten 'Total Revival' Stack

in Research/Science 42 upvotes 1 year ago

Cyclosporine A is discussed as a powerful hair growth stimulant, potentially more effective than minoxidil, but concerns about safety and side effects, including cancer risk, limit its use. The conversation highlights the need for further research and experimentation with topical application, despite its risks.

community Before and after? NO Fin/NO Minoxidil. Just DHT Blocking Shampoo&Microneedling

in Microneedling 54 upvotes 1 year ago

The user experienced hair thinning and used microneedling, DHT blocking shampoo, and Biotin DHT blocking oil to address it, avoiding finasteride and minoxidil unless necessary later. They reported mild improvement but received mixed feedback, with some suggesting other conditions or treatments like ciclopirox shampoo.

community Any other thing can increase the blood flow?

2 upvotes 4 years ago

community 6 months on minoxidil shedding again

269 upvotes 5 months ago

A user experienced hair shedding after six months of using topical minoxidil and is considering adding finasteride to their routine. Many suggest that minoxidil alone is insufficient for stopping hair loss and recommend combining it with finasteride or dutasteride for better results.

community hmi115 is coming. Prepare yourselves for what's coming

107 upvotes 3 years ago

The conversation discusses HMI-115, a potential cure for hair loss. Users share mixed opinions, with some expressing skepticism and others sharing anecdotal evidence of its effectiveness, including photos of significant hair regrowth from a trial participant.

community Pills for life Dutasteride 2.5mg+5mg oral Minoxidil 🤑

in Satire 37 upvotes 1 year ago

The conversation discusses using Dutasteride, oral Minoxidil, and other medications for hair loss, with the user expressing satisfaction despite potential side effects. The user prefers these treatments to maintain a youthful hairline, despite others suggesting alternative methods.

community Topical Minoxidil since April 2025. Finasteride since Sept 2025. Bald spot has gotten larger in area size and more noticeable in recent months. Trying to be patient but situation doesn’t seem to be resolving

7 upvotes 11 months ago

The user has been using topical Minoxidil since April 2025 and Finasteride since September 2025, but their bald spot has worsened. They are considering switching to oral Minoxidil and have been advised to be patient, see a dermatologist, and possibly try additional treatments like derma rolling.

community On the big 6 but very slow , needs acceleration

in Is this regrowth? 30 upvotes 1 year ago

The user is using a hair regrowth protocol including dutasteride, topical and oral minoxidil, dermarolling, ketoconazole shampoo, and tretinoin, but is experiencing slow progress and seeks advice for faster regrowth. Suggestions include quitting smoking, adjusting the regimen, and considering additional treatments like topical finasteride or RU58841.

community I can’t continue using oral minoxidil. I want to so badly though!

30 upvotes 1 year ago

The user experienced anxiety and heart pounding from oral minoxidil, despite its effectiveness, and switched back to topical minoxidil. After managing anxiety, they found oral minoxidil more effective, but side effects differ for each person.

community Quit vaping/smoking = 80% less loss

in Research/Science 235 upvotes 2 years ago

Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

community Should I take creatine if Im on fin?

9 upvotes 1 year ago

Creatine is unlikely to worsen hair loss for those on finasteride, with no strong scientific evidence linking it to increased hair loss. Many users report no negative effects on hair while using creatine.

community Brotzu lotion update

87 upvotes 8 years ago

A new hair loss lotion by Dr. Brotzu, expected to regrow up to 5 years of lost hair, is set to be released by Fidia Farmaceutici. It claims to work like minoxidil and finasteride without side effects, but skepticism exists due to its classification as a cosmetic product.

community 1.5 Year - Bad Results (HT, FIN, MINO, PRP, etc)

64 upvotes 2 years ago

A user shared their disappointing results after 1.5 years of hair treatments, including a hair transplant, finasteride, minoxidil, PRP, vegan shampoo, and more. They are considering switching to dutasteride, oral minoxidil, and improving their microneedling routine.

community Dental technician is convinced that he has found the cause of pattern hair loss

314 upvotes 2 years ago

A dental technician claims malocclusion causes pattern hair loss due to poor scalp circulation. Users debate this, noting treatments like finasteride, minoxidil, and microneedling focus on DHT and blood flow.

community 7 months fin, 10 months min, 4 months dut. Should I continue?

in Is this regrowth? 159 upvotes 2 years ago

The user has been using finasteride for 7 months, minoxidil for 10 months, and dutasteride for 4 months with minimal results and is considering stopping treatment. Replies suggest continuing treatment, adding microneedling, and checking DHT levels.

community Has anyone’s hair improved/saw more regrowth/thickening after quitting smoking cigarettes.

12 upvotes 2 months ago

Quitting smoking may improve hair quality and overall health, but it is not a standalone solution for reversing hair loss. Treatments like finasteride and minoxidil are more effective for hair regrowth, while smoking can exacerbate hair loss by increasing DHT and affecting scalp health.

community The Real Cause Of Androgenetic Alopecia

675 upvotes 1 year ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community This is the best time in human history to be fighting hair loss

195 upvotes 4 years ago

This conversation discusses the advancements in treatments for hair loss, including finasteride, dutasteride, minoxidil and new promising treatments such as pyrilutamide and verteporfin. Other treatments discussed were taking minoxidil orally, tretinoin to turn non-responders into responders and microneedling to further boost growth.

community 4.5 months/ Fin+Niz+Keto+Vitamins+Derm+Cold Water only washes

616 upvotes 5 years ago

User achieved hair regrowth in 4.5 months using Fin, Min, Nizoral, vitamins, dermarolling, and cold water washes. Cold water washes improved scalp health, but unsure if significant contributor to regrowth.

community Switching from Topical to Oral Minoxidil.

in Minoxidil 397 upvotes 1 year ago

Switching from topical to oral minoxidil for hair loss, with plans to use it alongside dutasteride. Users report mixed experiences, including increased body hair, potential heart-related side effects, and varying hair regrowth.

community My hair stopped falling out after I quit smoking

in Update 60 upvotes 1 year ago

Quitting smoking led to reduced hair loss for the original poster, who also used finasteride and topical minoxidil. Other users shared mixed experiences with smoking and hair loss, with some noticing improvements after quitting and others seeing no change.

community 10months on minoxidil as an “ok responder”

in Progress Pictures 205 upvotes 1 year ago

The user added topical minoxidil to their finasteride regimen, resulting in healthier hair and some regrowth, especially after quitting nicotine. They experienced minimal shedding and noted improvements in hairline density, finding the treatment mostly preventative.

community HMI 115 Phase 2 - Leaked pics from Discord

360 upvotes 2 years ago

The conversation discusses HMI 115, a new hair loss treatment with promising results, showing a significant increase in hair density after two months. Some users are skeptical, while others are hopeful for its release and potential affordability.

community Hair energiser tablets, useful or not?

2 years ago

A user is unsure if "Hair Energiser" tablets are effective for hair growth after a year of use. Replies suggest using finasteride instead and call the tablets a scam.