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GlossaryTUNEL-positive cells

cells undergoing programmed cell death with fragmented DNA

TUNEL-positive cells are cells that have been identified as undergoing apoptosis, or programmed cell death. The TUNEL (Terminal deoxynucleotidyl transferase dUTP Nick End Labeling) assay is a laboratory technique used to detect DNA fragmentation, a hallmark of apoptosis, by labeling the ends of broken DNA strands. This helps researchers and medical professionals understand cell death processes in various conditions, including diseases and tissue development.

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community Update: 16 months deep - big 3

in Progress Pictures 407 upvotes 1 year ago

The user has seen positive results after 16 months of using topical Finasteride/Minoxidil, microneedling weekly, and Tretinoin for hair loss. There are no reported side effects, and the user advises that the effectiveness of microneedling depends on the pressure applied.

community Post Finasteride Syndrome, A dangerous lie.

in Chat 142 upvotes 8 months ago

A user initially had side effects from finasteride, attributed them to anxiety and the nocebo effect, and after resuming the drug, experienced positive effects and now warns against misinformation about Post Finasteride Syndrome.

community Nothing's working, I feel depressed, also hopeless for the first time

in Update 102 upvotes 2 years ago

A user's experience with hair loss treatments, including Finasteride, Minoxidil, Nizoral Shampoo, Rosemary Oil, Vitamin D, Biotin, Vitamin C, Zinc and Dermarolling, that have not been successful over the past 14 months. Other users gave advice on how to cope with the issue, such as exercising, changing mindset, and shaving their head.

community Ultimate DHT/finasteride microdosing graph to replace the commonly one referenced on forums

in Finasteride/Dutasteride 204 upvotes 3 years ago

Hair loss treatments, specifically, discussing the effectiveness and side effects of finasteride, minoxidil, and RU58841 in various microdoses. It also includes an updated graph which provides information on how different doses affect DHT levels, scalp skin and serum androgen levels, as well as hair count.

community Why I really believe the tension theory is the cause of MPB

in Research/Science 70 upvotes 3 years ago

The conversation discusses the tension theory as a cause of male pattern baldness (MPB), suggesting that scalp tension and reduced subcutaneous fat layer contribute to hair loss. Treatments mentioned include Minoxidil, finasteride, microneedling, scalp massages, and Botox.

community CASSIOPEA ANNOUNCES VERY POSITIVE PHASE II TWELVE MONTHS RESULTS FOR BREEZULA® (CLASCOTERONE) IN TREATING ANDROGENETIC ALOPECIA

in Update 163 upvotes 5 years ago

Clascoterone (Breezula) showed positive results for treating hair loss without affecting cortisol levels. Opinions vary, with some users optimistic about its potential and others critical of its effectiveness compared to existing treatments like finasteride.

community Achievement Unlocked: Regrow Hairline

in Progress Pictures 272 upvotes 2 years ago

FluffyyKoala shared their 6-month hair regrowth journey using finasteride, minoxidil, and microneedling, with positive results and minimal side effects. Others in the conversation shared their experiences, asked questions, and congratulated FluffyyKoala on their progress.

community Almost 4 months of oral fin, topical min and microneedling

in Progress Pictures 752 upvotes 10 months ago

User "Mostuls" shared their 4-month hair loss treatment routine, which includes daily oral finasteride, twice-daily topical minoxidil, and microneedling twice a week with no side effects. Other users discussed the specifics of the treatment and expressed positive reactions to the results.

community Q1 2024 is done. And kintor is completely silent about GT20029.

in Research/Science 32 upvotes 7 months ago

The conversation discusses the lack of updates on GT20029 for hair loss treatment, with some users noting recent reports indicating ongoing data collection. There are mentions of other treatments like Pyrilutamide and Minoxidil.

community More great news about SCUBE3... this could be it!

in Research/Science 30 upvotes 1 year ago

SCUBE3 is a potential hair loss treatment that people are hopeful about. It may provide a solution without the side effects of finasteride.

community In my response to my previous post where someone said my hair was styled differently, now it’s styled the same in both pics.

in Is this regrowth? 380 upvotes 1 year ago

The conclusion of the conversation is that the user has experienced significant hair regrowth using a mixture of oils, including rosemary essential oil, peppermint essential oil, and carrier oils like castor oil or jojoba oil. The user also clarifies that both pictures were taken with damp hair.

community 2 years of Dutasteride. Not sure if I had proper MPB, or TE following drastic weight loss. But here it is (5 pics from then, and 6 from now).

in Progress Pictures 33 upvotes 1 year ago

User experienced hair thinning after losing 100 lbs and started Dutasteride treatment. They faced side effects like fatigue, brain fog, and insomnia but no erectile dysfunction.

community r/Tressless bros in a nutshell

in Satire 639 upvotes 7 months ago

The conversation discusses personal experiences with hair loss treatments, specifically Minoxidil and Finasteride, with some users regretting not starting treatment earlier and others experiencing side effects. Some users are considering or have switched to topical formulations due to side effects from oral medications.

community Shedding on finasteride only; looking for motivation

in Finasteride/Dutasteride 15 upvotes 7 months ago

A user started finasteride for hair loss and saw improvement, but is now experiencing shedding and thinning in new areas. They added Nizoral due to dandruff caused by finasteride. Replies suggest that shedding is normal around 6 months and advise to stick with the treatment.

community Dutasteride 1 year regression. Depressing. (With pictures for proof)

in Progress Pictures 14 upvotes 10 months ago

A user shared their experience of hair loss progression after one year on dutasteride, expressing disappointment with no improvement and considering other treatments like RU58841. Other users offered mixed responses, some seeing no change, others suggesting the hair loss might have been worse without treatment, and discussing the role of testosterone and DHT in hair loss.

community My hair journey: 2017 through the present

in Progress Pictures 504 upvotes 1 month ago

A user shared their hair loss journey from 2017 to 2024, detailing the use of finasteride, minoxidil, dutasteride, supplements, and dermarolling. They experienced significant hair loss after stopping finasteride in 2017, saw some regrowth after resuming treatments in 2023, and are considering a hair transplant.

community 27M exactly 3 months on Fin and Min results so far + my story

in Progress Pictures 4 upvotes 6 months ago

A 27-year-old shared his 3-month progress using finasteride and minoxidil for hair loss, showing significant improvement and increased confidence. He expressed gratitude to the community for their support and inspiration.

community Are most men bald because they haven’t tried any treatment or are they bald in spite of it?

in Shaved/buzzed 307 upvotes 6 months ago

Some men are bald because they are unaware of hair loss treatments like Minoxidil (Min) and Finasteride (Fin), while others choose not to use them due to potential side effects, cost, or personal preference. Treatments like Min and Fin are discussed, with varying results and opinions on their effectiveness and side effects.

community 19 yo destroyed hairline even though using Fin/min/microneedling for 16months/11months/3months … Idk what to do.

in Progress Pictures 259 upvotes 9 months ago

A 19-year-old has been using finasteride, minoxidil, and microneedling to treat hair loss with no regrowth, feeling mentally affected by it. Advice given includes continuing treatment, considering a hair transplant, addressing potential vitamin deficiencies, and possibly switching to dutasteride or adding ketoconazole shampoo.

community Finasteride vs Dutasteride: The Science

in Research/Science 167 upvotes 10 months ago

The conversation compares Finasteride and Dutasteride for hair loss treatment, discussing their effectiveness and side effects. Users share personal results and consider combining treatments like Dutasteride with RU58841.

community Have you noticed any difference in mood or energy since being on fin/dut?

in Finasteride/Dutasteride 25 upvotes 1 year ago

Users discuss effects of Finasteride/Dutasteride on mood and energy. Some experience depression, focus issues, and libido changes.

community 9 months fin+microneedling/2 years min, looks like there’s a light at the end of the tunnel

in Progress Pictures 100 upvotes 1 year ago

User shared 9-month progress with finasteride and microneedling, and 2-year progress with minoxidil for hair loss. Others asked about microneedling tools, routine, and suggested micro fibers for improvement.

community Exosome Hair Rejuvenation (2nd Month UPDATE!)

in Progress Pictures 3 upvotes 1 year ago

Hair loss discussion includes treatments like hinoki tree oil and procyanidin b2. Experiences and effectiveness of these treatments are shared.

community Why balding gets worse in every generation?

in Chat 81 upvotes 4 months ago

Balding seems to worsen with each generation, possibly due to stress, diet, and environmental factors. The user started treatments like Minoxidil and finasteride.

community I regrew my hairline in 2 years. Never give up hope. No transplant involved either.

in Progress Pictures 1071 upvotes 4 months ago

A user shared their 2-year hair regrowth journey using finasteride, ketoconazole shampoo, and a diet change, without a hair transplant. Despite skepticism from others, the user insists the results are natural and encourages consistency and dietary adjustments.

community Meta analysis: Topical or mesotherapy dutasteride is more effective than topical finasteride in the treatment of AGA in men

in Research/Science 19 upvotes 2 years ago

Topical Dutasteride is more effective than topical Finasteride for treating AGA in men, with fewer side effects. Mesotherapy with Dutasteride, administered every 3 months, shows promising results for hair regrowth and maintenance without daily routines or significant side effects.

community 2Y 5M on dut, ask me anything

in Finasteride/Dutasteride 137 upvotes 2 weeks ago

A user experienced significant hair regrowth using dutasteride without side effects, starting with finasteride and not using minoxidil or dermarolling. They attributed success to a unique genetic response to DHT blockers but did not share their full regimen, frustrating others.

community I just want to say hello to all my fellow Dutasteride Master Racers!

in Satire 64 upvotes 4 months ago

The conversation humorously discusses hair loss treatments, specifically Dutasteride. Users share experiences and joke about the high cost and effectiveness of the treatment.

community TresslessGPT is available to ChatGPT Plus users

in 📣 Announcement 107 upvotes 9 months ago

The conversation introduces a specialized chatbot for ChatGPT Plus users that provides advice on hair loss treatments, drawing from research and community insights. It mentions treatments like RU58841, the "big 4" (likely minoxidil, finasteride, ketoconazole, and tretinoin), dutasteride mesotherapy, topical melatonin, microneedling, and rapamycin.

community About Verteporfin but not about hair

in Technology 17 upvotes 11 months ago

Verteporfin treatment shows promise for hair regeneration and reducing scar tissue in hair transplants. Some users plan to try verteporfin with hair transplants, and it may also be combined with PRP in future experiments.