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Did you mean Testosterone Metabolism?

GlossaryTestosterone Metabolism

process of breaking down and converting testosterone in the body

Testosterone metabolism refers to the process by which the body breaks down and converts testosterone, a key male sex hormone, into other substances. This involves enzymes that transform testosterone into dihydrotestosterone (DHT) and estradiol, which play crucial roles in various bodily functions, including hair growth and sexual development. Understanding this process is important for addressing conditions like alopecia, where DHT can contribute to hair loss.

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community Having androgen receptor density and sensitivity at wrong f*ing place

in Satire 7 upvotes 1 month ago

The conversation discusses hair loss treatments, focusing on the use of topical minoxidil, microneedling, finasteride, and dutasteride, while debating the role of testosterone and DHT in hair loss. It also touches on the potential liver health impacts of these treatments and the genetic sensitivity of hair follicles to androgens.

community 6 months of microneedling, minox, 1% keto, & biotin. Time for fin?

in Progress Pictures 329 upvotes 1 year ago

User experienced hair growth after 6 months using microneedling, minoxidil, ketoconazole, and biotin. Commenters suggest adding finasteride to treatment for better results and preventing further hair loss.

community Saying creatine causes loss on fin/dut makes no sense and this is why

in Finasteride/Dutasteride 42 upvotes 9 months ago

The conversation discusses whether creatine causes hair loss for those using finasteride or dutasteride, with some suggesting creatine might increase DHT or upregulate androgen receptors, potentially leading to hair loss. Others argue the evidence is not conclusive, citing limited studies and personal anecdotes, with some avoiding creatine as a precaution.

community Creatine and Finasteride together - still started losing hair

in Finasteride/Dutasteride 20 upvotes 1 year ago

User experienced hair loss after taking creatine with finasteride for 8 years. Others shared similar experiences, but some suggested it could be a minoxidil shed.

community Boys I am just a gonner. What on earth is my scalp even going through. Looks like world war 3. Pyril 3 months. Topical melitonin/progesterone/fin, dut, fin, oral min, laser trash, anus stimulation. Nothing. Donor area is decimated 😂.

in Progress Pictures 83 upvotes 2 years ago

Treating Seborrheic Dermatitis, a fungal scalp condition which can cause hair loss. Treatments discussed include antifungal shampoos, cold showers, exfoliating the scalp, taking Vitamin D, and stimulating the prostate through the anus.

community What is the real impact of dutasteride on neurosteroids? A little review of 2 scientific datas

in Research/Science 21 upvotes 4 months ago

Dutasteride at 0.5 mg/day does not significantly alter allopregnanolone levels, but higher doses (2.5 mg/day) do. Dutasteride may also have anti-neuroinflammatory effects, but the impact on neurosteroids is still debated.

community Ronaldo and his Brothers Hairline (10 years difference)

in Chat 498 upvotes 4 months ago

Ronaldo's hairline remains sharp, while his brother's is receding. Opinions vary on whether Ronaldo uses treatments like finasteride or has had hair transplants, with some attributing his hairline to genetics and others to possible medical interventions.

community My Testosterone results before and after Finasteride

in Update 146 upvotes 3 years ago

Finasteride significantly increased testosterone levels for the user, with no major side effects except watery semen, which was resolved with zinc supplements. The user's hairline stopped receding and slightly improved.

community Why is it that low testosterone causes hair loss as well? How can I be balding?

in Chat 158 upvotes 7 months ago

The conversation discusses the confusion over low testosterone potentially causing hair loss, with users sharing personal experiences and knowledge about hair loss treatments like Finasteride. Some users suggest that hair follicle sensitivity to DHT, not testosterone levels, is the key factor in balding, and others discuss the side effects of hair loss medications.

community How to Keep Your Hair on Steroids

in Treatment 16 upvotes 2 months ago

To minimize hair loss while using steroids, use finasteride or dutasteride and apply topical anti-androgens like RU58841. Avoid high doses of hair-toxic steroids; prefer testosterone, nandrolone, and boldenone.

community Is this broscience? From More Plates, More Dates

in Research/Science 22 upvotes 8 months ago

The conversation discusses whether finasteride's reduction of DHT and increase in scalp testosterone contribute to hair follicle miniaturization. Some participants argue testosterone does not cause miniaturization, while others suggest that even with reduced DHT, other androgens like testosterone may still contribute to hair loss.

community What Works to Restore Hairloss for Cis-Males? Not Much

in Treatment 18 upvotes 4 years ago

Hair regrowth treatments for cis-males include Minoxidil, Finasteride, and RU58841. Estrogen and testosterone blockers can help restore hair loss but may not suit everyone.

community My hair after 3 steroid cycles

in Progress Pictures 25 upvotes 4 months ago

A user shared their hair progress after three steroid cycles, using 5% minoxidil and 100mg RU58841 daily. They are considering a hair transplant due to paranoia about shedding.

community Nandrolone Replacement Therapy

in Treatment 41 upvotes 1 year ago

A user discusses starting nandrolone replacement therapy to stop hair loss and improve hair health, noting its benefits over finasteride. They report halted hair loss, improved skin, increased muscle, and a calm mood after three weeks.

community Trestolone (MENT) as a nuclear treatment

in Treatment 99 upvotes 2 years ago

Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.

community Hey guys I’m a Compounding Pharmacist specialized in Hair-loss who makes Topical Finasteride Foam +/- minoxidil

in Treatment 28 upvotes 3 years ago

A compounding pharmacist offers affordable topical finasteride foam with Anagain and micro-dose finasteride capsules for hair loss. They provide telehealth services across Canada and private appointments for international patients.

community Guide To Finasteride and Avoiding Side Effects

in Finasteride/Dutasteride 25 upvotes 2 years ago

The conversation provides a guide on using finasteride for hair loss, suggesting to start with a quarter of a 1mg pill daily after ensuring estradiol levels are within a specific range, and potentially increasing the dose if no side effects occur. It also recommends supplements like DIM, Calcium d-glucarate, and Zinc to manage high estradiol levels and side effects from finasteride.

community High Nicotine use and Hair Loss

in Chat 79 upvotes 3 months ago

Heavy nicotine use can lead to hair thinning and loss, but quitting can reverse these effects. The user noticed significant hair regrowth after quitting vaping.

community 15 years of finasteride/minoxidil

in Update 194 upvotes 6 months ago

A user shared a 15-year experience using minoxidil and finasteride for hair loss, stating that despite never missing a dose, their hairline continued to recede slowly. Other users suggested that the hair loss might be exacerbated by the use of steroids and recommended considering other treatments like dutasteride and RU58841.

community I find it funny a bunch of us on here are on drugs for hairloss and maintain clean/healthy lives and then there’s these mf’s in the 90’s juiced to the gills with steroids and have better hair than all of us lol

in Satire 353 upvotes 1 year ago

The conversation is about the effects of steroids on hair loss. Some users believe that steroids can cause hair loss, while others argue that it depends on individual sensitivity to DHT. There is also discussion about the appearance of balding individuals who use steroids.

community Bloodwork: what to test for?

in Finasteride/Dutasteride 7 upvotes 4 years ago

The user has been taking oral Finasteride and topical Essengen 6 Plus for hair loss and is experiencing increased depression. They plan to get bloodwork to check hormone levels and are seeking advice on which tests to include.

community Zix + Topical Fin : Blood Test Before/After, AMA and suggestions

in Treatment 48 upvotes 4 years ago

A user's plan to use Zix and topical finasteride (5AR inhibitors) for hair loss, followed by blood testing before/after. The user has suggested creating a fund to cover part of the cost of their blood tests. Replies to their post discuss the effectiveness of the treatments.

community Update: Chest discomfort from RU58841

in Update 34 upvotes 9 months ago

A user experienced severe chest pains and shortness of breath after using RU58841 for hair loss and was advised by a doctor that blocking androgens can weaken the heart. They decided to continue with finasteride, minoxidil, and a hair transplant instead.

community I've been afflicted by post finasteride syndrome, what now?

in Finasteride 42 upvotes 5 years ago

A user experienced severe side effects from finasteride, including mental health issues and physical symptoms, and sought advice on managing post-finasteride syndrome. Suggestions included checking vitamin levels, considering dopamine agonists, and avoiding further psychiatric medications.

community How I started reversing Male Pattern Baldness naturally ?

in Question 6 upvotes 7 years ago

The user reversed male pattern baldness using a pro-thyroid diet, lifestyle changes, and scalp stimulation exercises, without Minoxidil or Finasteride. They reported reduced dandruff, itchiness, oiliness, and experienced hair regrowth and thickening over 15 months.

community Pyrilutamide ,the molecule’s true nature

in Research 302 upvotes 3 months ago

Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

community What else can I do to compliment Minoxidil?

in Update 4 upvotes 1 year ago

A user has been using minoxidil for hair loss and has seen positive results, but is seeking additional treatments to enhance its effects. One suggestion given is to use finasteride alongside minoxidil.

community 18->24 six years of Fin and Minox…. I guess we can’t all be winners 😭

in Progress Pictures 572 upvotes 2 years ago

A user named "EgyptStar81" who has been dealing with hair loss since age 15 due to genetics, chemotherapy and finasteride/minoxidil treatment. Possible solutions such as dutasteride, oral minoxidil, hair transplants and extensions were suggested.

community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

in Treatment 98 upvotes 4 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community Is there a topical androgen receptor blocker so we don't have to fuck with the enzyme and destroy our allopregnanolone, but go and hit the end target straight?

in Treatment 47 upvotes 5 months ago

The conversation discusses topical androgen receptor blockers for hair loss, mentioning Clascoterone, Pyrilutamide, GT20029, and RU58841. Ketoconazole's effectiveness and application methods are also debated.