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Glossaryspheroids

three-dimensional cell clusters used for more accurate tissue studies

Spheroids are three-dimensional cell cultures that mimic the structure and function of tissues more accurately than traditional two-dimensional cultures. In the context of hair and alopecia research, spheroids can be used to study hair follicle biology and test potential treatments in a more physiologically relevant environment.

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community Surprisingly thorough study on He-Shou-Wu/Fo Ti

in Research/Science 14 upvotes 1 year ago

He Shou Wu (Fo Ti) extract was found to prolong the hair growth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.

community How to Keep Your Hair on Steroids

in Treatment 19 upvotes 3 months ago

To minimize hair loss while using steroids, use finasteride or dutasteride and apply topical anti-androgens like RU58841. Avoid high doses of hair-toxic steroids; prefer testosterone, nandrolone, and boldenone.

community I find it funny a bunch of us on here are on drugs for hairloss and maintain clean/healthy lives and then there’s these mf’s in the 90’s juiced to the gills with steroids and have better hair than all of us lol

in Satire 353 upvotes 1 year ago

The conversation is about the effects of steroids on hair loss. Some users believe that steroids can cause hair loss, while others argue that it depends on individual sensitivity to DHT. There is also discussion about the appearance of balding individuals who use steroids.

community I'm regrowing my hair while being on the harshest steroids

10 upvotes 6 years ago

The user is regrowing hair while using steroids by following a regimen that includes Rogaine, RU58841, Dutasteride, Nizoral, PGE2, and occasionally castor oil. Despite using harsh steroids like Tren, Masteron, and Proviron, the user reports successful hair regrowth.

community Ru-58841 vs KX-826/pyrilutamide while on steroids

in Finasteride/Dutasteride 3 upvotes 1 month ago

The user increased their steroid dosage and noticed hair shedding, so they adjusted their regimen by reducing steroid doses and adding oral dutasteride. They are also experimenting with combining RU-58841 and KX-826/pyrilutamide in minoxidil to address hair loss.

community I find it crazy how some people like this bloke have 0 DHT sensitivity. He is on grams of anabolic steroids and has a full, thick head of hair. I wish all of on here had this guys hair genes lol

in Satire 443 upvotes 1 year ago

The conversation is about hair loss and the possibility of maintaining a full head of hair while using anabolic steroids. Some users believe that having good hair genes and taking hair loss protocols can help prevent hair loss while on steroids.

community Derm says my hair loss (diffuse) is from seborrheic dermatitis. Anyone else have experience with this? I was already prepared to jump on fin min

in Research/Science 25 upvotes 3 weeks ago

Seborrheic dermatitis can cause hair loss, and treatments like ketoconazole shampoo, topical steroids, and oral antifungals may help. Some consider using finasteride and minoxidil for hair loss despite dermatitis.

community 15 years of finasteride/minoxidil

in Update 194 upvotes 7 months ago

A user shared a 15-year experience using minoxidil and finasteride for hair loss, stating that despite never missing a dose, their hairline continued to recede slowly. Other users suggested that the hair loss might be exacerbated by the use of steroids and recommended considering other treatments like dutasteride and RU58841.

community How is it that golden era bodybuilders kept their hair while blasting gear while in the modern era most are bald? I’m convinced there’s something in our food and water causing MPB to speed up

in Satire 729 upvotes 1 year ago

The conversation is about the difference in hair loss between bodybuilders in the "Golden Era" and modern bodybuilders. Some users speculate that factors such as the types and doses of steroids used, genetics, diet, microplastics, and overall health may contribute to hair loss. Hair loss prevention medication and transplants are mentioned as potential treatments.

community Hair gains about 11 months in between pics! Stack is below.

in Progress Pictures 5 upvotes 1 year ago

User experienced hair growth after 11 months using 15% Minoxidil, topical and oral Finasteride, and Ketoconazole Shampoo. Hair remained full even while using steroids and SARMs.

community Has anyone figure out how to deal with their itchy scalp when most ingredients aren't working?

in Treatment 6 upvotes 2 years ago

The user has chronic itchy scalp and dandruff, unresponsive to ketoconazole, selenium sulfide, zinc pyrithione, coal tar, and salicylic acid. Topical steroids were also ineffective for long-term use.

community 2020 Hair and Scalp Treatments: A Clinical Guide (in Depth 350 Page Guide)

in Treatment 64 upvotes 4 years ago

Treatments for hair loss, including topical immunotherapy, regenerative treatments, laser and light-based therapies, oral supplements, intralesional steroids, and new drugs like finasteride and minoxidil.

community Hairline Slowly Growing Back On It's Own After Seborrheic Dermatitis

10 upvotes 5 years ago

The user treated seborrheic dermatitis by cutting sugar, improving sleep, using four different shampoos, and occasionally using steroids. Their hair is growing back thicker and new hair is appearing.

community TIL about Alfatradiol, a topical DHT blocker. Has anyone else ever heard or read about this? Or used it?

6 upvotes 10 years ago

Hair loss treatments, including Alfatradiol, Minoxidil, Finasteride, and RU58841. It discusses the efficacy of these treatments for hair growth and regrowth.

community Ted Kaczynski had more hair than all you mfs before his death at 81

in Satire 1771 upvotes 1 year ago

The conversation is about hair loss and the conclusion is that genetics play a significant role in hair loss, and lifestyle choices or being a well-adjusted person do not prevent male pattern baldness.

community Can I use topical steroid along finasteride to reduce scalp inflammation and hairloss?

in Finasteride 6 upvotes 6 years ago

The user asks if finasteride can be used with the topical steroid betamethasone dipropionate to reduce hair loss and scalp inflammation. The discussion revolves around combining these treatments for better results.

community The 'DHT itch' is real - notes from a casual bodybuilder

in Chat 115 upvotes 3 months ago

The "DHT itch" is real and likely due to inflammation at the hair follicle, exacerbated by increased testosterone or androgens. Treatments mentioned include dutasteride, minoxidil, finasteride, and various topical solutions.

community Anyone else feel like a victim of medical misinformation towards finasteride?

in Finasteride/Dutasteride 65 upvotes 4 months ago

Users discuss their experiences with finasteride, expressing regret over delayed use due to misinformation and sharing mixed outcomes, including side effects and benefits. Treatments mentioned include finasteride, dutasteride, and minoxidil.

community Trestolone (MENT) as a nuclear treatment

in Treatment 99 upvotes 2 years ago

Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.

community Debunking the "Adverse metabolic consequences of dutasteride"

in Research/Science 40 upvotes 3 years ago

Dutasteride is more effective than finasteride, has neuroprotective benefits, and may prevent acne. Despite initial concerns about metabolic effects, further research suggests it is safe for most users, especially if not hypogonadal.

community Losing hair everywhere, idk what to do :(

29 upvotes 5 years ago

A 22-year-old male has been experiencing widespread hair loss for over four years, including pain and significant shedding. Treatments tried include ketoconazole shampoo, fluocinonide topical solution, biotin, ACV, and dry shampoo, but none have been effective.

community How important are Retinoic and Hydrocortisone in topical serum?

in Treatment 4 upvotes 2 weeks ago

The conversation is about using a topical serum for hair loss with ingredients like finasteride and minoxidil, and the option to exclude retinoic acid and hydrocortisone due to concerns about long-term effects. One user prefers using only finasteride, avoiding minoxidil and retinoic acid, and plans to remove hydrocortisone in future orders.

community What happens to the excess testosterone after using dut?

in Finasteride/Dutasteride 23 upvotes 3 weeks ago

Using dutasteride or finasteride can increase free testosterone, which may convert to estradiol, potentially causing side effects like increased estrogen levels. Individual responses vary, and some users report changes in cholesterol, hair texture, and side effects like gyno or increased sex drive.

community any Ru58841 user ? + What do I need to expect?

in Product 9 upvotes 1 month ago

The user is considering adding RU58841 to their current hair loss treatment of finasteride and minoxidil, but is concerned about potential side effects like hairline recession and shedding. Some users report positive results with RU58841, while others experience side effects such as chest pain and dizziness.

community 2.5 years Minoxidil and HRT, CPA->Lupron +Minox 5%

in Transgender 611 upvotes 1 month ago

The user experienced significant hair regrowth after 2.5 years of using Minoxidil 5% and hormone replacement therapy (HRT) with Lupron, despite initial scalp irritation. Finasteride was ineffective for them.

community Two month transformation with 2mg Fin daily, Minoxidil, Nizoral twice a week and Biotin shampoo every day.

in Progress Pictures 9 upvotes 1 month ago

The user experienced a noticeable hair transformation in two months using 2mg finasteride daily, minoxidil, Nizoral shampoo twice a week, and Biotin shampoo daily. They reported initial side effects from finasteride but saw quick results despite occasional hair shedding.

community this community is so funny bro

in Satire 1787 upvotes 1 month ago

Hair loss treatments like finasteride, minoxidil, and dutasteride are discussed, with users sharing mixed experiences about effectiveness and side effects. Some users report positive results, while others express concerns about side effects, highlighting the importance of personal choice.

community 2Y 5M on dut, ask me anything

in Finasteride/Dutasteride 130 upvotes 2 months ago

A user experienced significant hair regrowth using dutasteride without side effects, starting with finasteride and not using minoxidil or dermarolling. They attributed success to a unique genetic response to DHT blockers but did not share their full regimen, frustrating others.

community Hairsystem before/after (my journey from balding -> HT -> bald -> System)

in Hair Systems 407 upvotes 2 months ago

A user shared their journey from balding to using a hair system, expressing satisfaction with the results despite the costs. They mentioned trying finasteride but stopped due to side effects, and now enjoy increased attention from women with the hair system.

community How does hair loss and recovery work?

in Chat 12 upvotes 3 months ago

Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.