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      community Take licorice to lower testosterone?

       1 upvotes 9 years ago
      Licorice is not recommended for hair loss as it inhibits hair growth and is a non-selective testosterone inhibitor. Alternatives like spironolactone are suggested for those considering hormonal treatments for hair loss.

      community Alternatives/unorthodox hairloss protocols to the big three

      in Chat  1 upvotes 8 months ago
      The conversation discusses alternative and unorthodox hair loss treatments, including RU58841, nandrolone, and dianabol, as well as theoretical approaches involving high doses of estrogen and selective estrogen receptor modulators. These methods are considered extreme and potentially harmful but are explored for those unable to tolerate traditional 5-alpha reductase inhibitors.

      community PP405 - A True Breakthrough or Another Disappointment?

       34 upvotes 1 year ago
      PP405 shows potential for hair growth, with 31% of advanced balding men experiencing over 20% increase in hair density in 8 weeks. However, skepticism persists due to selective data presentation and lack of long-term results, with comparisons to treatments like minoxidil and finasteride.

      community Clascoterone study going on right now

       351 upvotes 2 years ago
      A user is participating in a phase 3 trial for Clascoterone, a topical acne medication that may stimulate hair growth, and will share results after 6 months. They will have a section of their hair shaved and marked with a tattoo for the study.

      community Why are low finasteride doses seen as highly ineffective, when studies show 0.05 mg/day to work?

      in Finasteride/Dutasteride  38 upvotes 4 years ago
      The efficacy of low doses of finasteride to reduce scalp DHT, and whether studies showing a 61% reduction are reflected in actual results. Replies discussed hair growth as an unintended consequence of minoxidil and finasteride use, as well as self-selective bias, potential side effects, and that studies measure effectiveness by hair count changes rather than DHT inhibition.

      community Choose your topical antiandrogen and tell me why

       6 upvotes 2 years ago
      The conversation is about choosing a topical antiandrogen for hair loss, with options including RU58841, CB0301, Pyrolutamide, Alfatradiol, and Fluridil. Users discuss their preferences and reasons for selecting specific treatments.

      community Is my current doseage viable? (Trans)

       3 upvotes 11 months ago
      The user is taking Dutasteride, Finasteride, Estradiol, Spironolactone, and Progesterone for hair regrowth and is considering adding Minoxidil and rosemary oil. They are experiencing some hair regrowth and are consulting a dermatologist to avoid a hair transplant.

      community Study on Sugar Intake on Male Pattern Hair Loss

       19 upvotes 3 years ago
      Excessive sugar and high-fat diets are linked to male pattern hair loss, with sweet beverages being a significant factor. Moderation in diet is advised, as diet alone may not fully prevent hair loss due to other factors like DHT sensitivity.

      community Falied transplant? Or just no meds?

       96 upvotes 4 weeks ago
      Slaven Bilić's hair appears to use fibers, with noticeable gaps and color changes. He likely had a hair transplant but didn't use medications, leading to hair loss in non-transplanted areas.

      community Hair Oil Recipe: what should the ratio be?

      in Chat  5 upvotes 2 years ago
      The conversation is about creating a hair oil using peppermint oil, Mielle Rosemary Oil, black Jamaican castor oil, and coconut oil. Users suggest that oils alone won't help with male pattern baldness without using treatments like finasteride or minoxidil.

      community Should i start meds or see another dermatologist?

       5 upvotes 7 months ago
      The user is experiencing unexpected hair thinning and is considering starting finasteride and minoxidil after a dermatologist's brief assessment. They are hesitant and seeking opinions, with some users suggesting finasteride alone might be sufficient for mild hair loss.

      community 15 months on finastride minoxidil

       87 upvotes 1 month ago
      After 15 months on finasteride (1mg every second day) and topical minoxidil, the user noticed new hair growth and fuller hair without side effects. The user is 29 years old and observed visible improvement after one year.

      community Phase 3 for PP405 will now start in 2027

      in Chat  81 upvotes 1 month ago
      Phase 3 for PP405 will start in 2027, disappointing many who expected it this year. Some users are trying treatments like topical minoxidil and topical dutasteride while waiting for new developments.

      community A Short Recap on PP405 and AAD 2026

      in Update 5 months ago
      PP405 is a promising experimental topical treatment for alopecia that reactivates dormant hair follicles by targeting cellular energy, with large-scale trials planned for 2026. While it shows potential, it cannot regenerate permanently destroyed follicles, making hair transplants the only guaranteed solution for advanced baldness currently.

      community 4 months apart (aug 15 - dec 19)

      in Progress Pictures  538 upvotes 1 year ago
      The user shared progress pictures showing hair improvement over four months using 1 mg finasteride and 5 mg minoxidil daily. They reported no significant side effects and plan to reduce the minoxidil dose once satisfied with the results.

      community My summation of PP405 - looks promising

       210 upvotes 1 year ago
      PP405 shows promise for hair regrowth by manipulating stem cell characteristics and lactate dehydrogenase, with Phase 2a trials pending. Google Ventures' $15M investment suggests confidence, but results and market availability remain uncertain.

      community Being Safe on Oral Minoxidil: tl;dr on the literature.

       51 upvotes 1 year ago
      Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.

      community Dutasteride causing us to have… girl babies?

      in Finasteride/Dutasteride  26 upvotes 3 years ago
      User Kylo313 used dutasteride for 20 years and had two daughters, questioning if dutasteride affects the likelihood of having male vs female children. Replies mostly request hairline photos and discuss anecdotal experiences, with some suggesting correlation doesn't imply causation and that gender determination isn't affected by dutasteride.

      community Justifications for starting Finasteride

       12 upvotes 5 years ago
      An 18-year-old decided to start taking finasteride for hair loss, justifying it by stating that finasteride is the most effective treatment available and that the risk of side effects is low, with clinical trials showing it stops hair loss in 80% of men. The user encourages others not to be deterred by negative forum posts and to consider their own experience and clinical data.

      community Why I’d advise my teenage son to take propecia (opinion)

       5 upvotes 5 years ago
      The post argues for teenage use of finasteride to prevent hair loss, citing minimal side effects and personal success. Replies criticize the advice, highlighting potential developmental risks and questioning the safety of finasteride for teenagers.

      community Doctor prescribed me Spironolactone instead of Finasteride

       13 upvotes 4 days ago
      The user was prescribed topical Spironolactone instead of Finasteride for hair loss, but is concerned about its effectiveness and potential side effects. Other users suggest that topical Spironolactone is safe for men, but Finasteride might be a more common and effective choice.

      community long hair + minoxidil spray, how do you actually cover the whole scalp?

       7 upvotes 3 weeks ago
      The conversation discusses applying minoxidil for hair loss, with users suggesting using a dropper or oral minoxidil instead of spray for better scalp coverage. Techniques like using a comb or applicator comb are recommended for more effective application.

      community My hormone levels after 2 months of Finasteride and 2 weeks of Dutasteride

       12 upvotes 3 weeks ago
      The conversation discusses elevated hormone levels after using Finasteride for 2 months and Dutasteride for 2 weeks for hair loss. Users suggest that increased testosterone and estradiol levels are expected due to DHT inhibition, and it's not a concern unless symptoms occur.