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GlossaryProstate Cancer Cells

abnormal cells originating in the prostate gland, potentially spreading

Prostate cancer cells are abnormal cells that originate in the prostate gland, a small gland in men that produces seminal fluid. These cells can grow uncontrollably and form tumors, potentially spreading to other parts of the body (metastasis). Also known as prostate carcinoma cells, they are the focus of various diagnostic and treatment strategies in oncology.

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community Dutasteride: More Than a DHT Reducer – A Potential Androgen Receptor Inhibitor?

in Finasteride/Dutasteride 30 upvotes 2 days ago

Dutasteride may inhibit androgen receptors in addition to reducing DHT, potentially explaining its effectiveness over finasteride for hair loss. Concerns about its impact on muscle growth are debated, with some suggesting no significant effects.

community Looks like Kintor finished enrollment and dosing of phase 1 for gt20029 in China.

in Chat 24 upvotes 2 years ago

The conversation discusses the potential of a new hair loss treatment, GT20029, which targets androgen receptors in the scalp and is in phase 1 trials in China. Users express hope that this treatment will be more effective than current options like Minoxidil and Finasteride.

community Debunk the debunk ? - Not sure but this study still exists ...

in Research/Science 24 upvotes 3 years ago

The conversation discusses hair loss treatments, specifically mentioning Minoxidil, finasteride, and RU58841. It highlights a study suggesting that sulforaphane may reduce DHT levels and promote hair growth in mice.

community Why does finasteride stop working?

in Finasteride/Dutasteride 26 upvotes 2 months ago

Finasteride may seem less effective over time due to increased DHT sensitivity or aging, but it still suppresses DHT. Switching to dutasteride offers stronger DHT suppression but may increase estrogen levels.

community Why is nobody studying the difference between donor and balding hair?

in Chat 89 upvotes 6 months ago

The conversation discusses why the difference between donor and balding hair isn't studied more to find a cure for hair loss. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Rosemary oil, peppermint oil, mucuna pruriens - two weeks in

in Treatment 84 upvotes 1 year ago

A user who is trying alternative treatments, such as mucuna pruriens dissolved in water/alcohol and a blend of jojoba oil, rosemary oil, and peppermint oil, for hair loss. Other users have shared anecdotal evidence, discussed the potential effectiveness of certain treatments, and questioned the time sensitivity of experimenting with new treatments.

community Dutasteride takes 1-3 months to work in the scalp. Not weeks. Be careful.

in Finasteride/Dutasteride 41 upvotes 4 months ago

Dutasteride takes 1-3 months to affect scalp DHT levels, not just a week. The prostate absorbs Dutasteride faster than the scalp due to different vascular networks and enzyme densities.

community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens.

in Research/Science 1 upvotes 2 weeks ago

A method for treating androgenic alopecia using minoxidil, antiandrogens, exercise, and cold exposure to promote hair growth. Environmental factors and lifestyle changes, like diet and exercise, can improve treatment effectiveness.

community Why haven’t we seen anything about this

in Research/Science 18 upvotes 4 years ago

A double blind, placebo-controlled study that looked into the potential effectiveness of topical fluridil for treating male androgenetic alopecia, showing increased anagen to telogen ratios with no reported side effects on libido or sexual performance.

Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens

community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens

in Research 413 upvotes 2 weeks ago

Treating androgenic alopecia with minoxidil, finasteride, and antiandrogens, alongside exercise, cryotherapy, and natural substances to stimulate cold receptors for better hair growth. The method focuses on enhancing treatment effectiveness by considering environmental and behavioral factors and the role of cold receptors and muscle stress.

community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001) Pt 2

in Research/Science 479 upvotes 4 months ago

Sugary beverages increase the risk of pattern hair loss in men by 57%. Treatments discussed include Minoxidil, finasteride, and RU58841.

community Dermarolling is a bit sad innit?

in Microneedling 232 upvotes 3 years ago

Hair loss treatments discussed include dermarolling, minoxidil, finasteride, and RU58841. Some users find dermarolling sad, while others mention the complexity of biological systems and limited research funding for hair loss.

community Finasteride is Good for Heart Health!

in Research/Science 119 upvotes 10 months ago

Finasteride, a hair loss and prostate drug, may also benefit heart health. Some users discuss the potential negative effects of DHT on the heart and the balance between hair loss treatments and heart health.

community My hairloss started at 17 - Transformation. Bald to full head of hair.

in Research/Science 2 months ago

The user shared their journey from hair loss at 17 to a full head of hair using topical finasteride, Saw Palmetto, a natural serum with stem cells and rosemary oil, dermarolling, and a specialized shampoo. They experienced side effects with Dutasteride and found success with their current routine without side effects.

community Dermatologist told me to quit fin after turning 40

in Finasteride/Dutasteride 194 upvotes 1 year ago

A dermatologist advised a patient to stop taking finasteride (fin) after turning 40 due to potential risk of aggressive prostate cancer. The patient and others in the conversation debated this advice, discussing the relationship between finasteride, prostate cancer, and hair loss, and considering alternatives like topical finasteride.

community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

in Research/Science 743 upvotes 2 years ago

A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

community I would like to know Barcelona keeper Ter Stegen’s hair growth regimen

in Is this regrowth? 399 upvotes 1 year ago

Barcelona goalkeeper Ter Stegen's hair growth regimen, which is believed to include a transplant and other treatments such as finasteride, minoxidil, PRP injections, DUT injections, and possibly stem cells.

community Do you believe there will be a game changing treatment in the next 10 years?

in Chat 67 upvotes 2 years ago

Users discuss potential game-changing hair loss treatments in the next 10 years. Some mention KX-826, SCUBE3, and stem cells as promising options, while others express doubt due to past disappointments and lack of focused research.

community Boys I am just a gonner. What on earth is my scalp even going through. Looks like world war 3. Pyril 3 months. Topical melitonin/progesterone/fin, dut, fin, oral min, laser trash, anus stimulation. Nothing. Donor area is decimated 😂.

in Progress Pictures 83 upvotes 2 years ago

Treating Seborrheic Dermatitis, a fungal scalp condition which can cause hair loss. Treatments discussed include antifungal shampoos, cold showers, exfoliating the scalp, taking Vitamin D, and stimulating the prostate through the anus.

community Mechanism of action of alfatradiol (17 alpha estradiol)

in Research/Science 6 upvotes 6 months ago

The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.

community The day they make a pill that only targets DHT production in the scalp

in Finasteride/Dutasteride 29 upvotes 1 month ago

Reducing DHT in the scalp is ideal for hair retention, with topical finasteride and dutasteride being common treatments. Some users report side effects like reduced libido, while others experiment with higher doses for regrowth.

community I enjoy taking finasteride every day

in Finasteride/Dutasteride 241 upvotes 7 months ago

Users discuss their positive experiences with finasteride for hair loss, mentioning halted hair loss, hair regrowth, and improved self-esteem. Some express satisfaction in taking action against baldness, while others note increased libido and energy.

community Is it possible for androgenic alopecia to begin at early adolescent years?

in Chat 70 upvotes 1 year ago

Hair loss can begin in early adolescence and cause mental anguish. Treatments mentioned include eating cruciferous vegetables, engaging in physical activity, and maintaining scalp hygiene.

community PCOS female with significant receding and thinning; doctor won’t give me anything but Spiro and Spiro sucks

in Female 6 upvotes 2 years ago

Female with PCOS experiences receding and thinning hair, wants dutasteride instead of spironolactone. Discusses desire to reduce DHT without losing libido.

community Progress from August to November

in Progress Pictures 965 upvotes 3 weeks ago

A user shared their hair regrowth progress from using Minoxidil 5% and Finasteride 2.5 mg since August 2024, reporting no side effects. They cut 5mg Finasteride pills in half and take them every other day, and recommend consulting a dermatologist for personalized advice.

community Expectations control for SCUBE3

in Research/Science 21 upvotes 9 months ago

SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

community 48M, 11 month progress, 1MG finasteride only

in Progress Pictures 627 upvotes 1 year ago

A 48-year-old man's 11-month progress using 1mg finasteride for hair loss treatment, with significant improvement and no side effects. Other users share their experiences, with some also seeing positive results, while others have not been as successful.

community Pyrilutamide update: three months

in Update 32 upvotes 1 year ago

A user's 3-month experience with pyrilutamide to reduce hair shedding, and how it may not be strong enough to stop the thinning of their hairline. Other users mentioned the effectiveness of minoxidil and finasteride for treating hair loss.

community Scientific Review: Saw Palmetto is not effective for treating hair loss and does not inhibit DHT to the extend that most people think. Anti-Hair loss claims are invalid.

in Research/Science 35 upvotes 2 years ago

Saw Palmetto is not effective for hair loss treatment and is not a recommended alternative to finasteride due to its inability to significantly inhibit DHT.

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 449 upvotes 3 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.