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Glossarypermeation

movement of substances through a membrane or porous material

Permeation refers to the process by which a substance, such as a liquid or gas, passes through a porous material or membrane. In the context of hair and scalp treatments, permeation is crucial for understanding how active ingredients in topical products penetrate the skin and hair follicles to exert their effects. This process is influenced by factors like the molecular size of the substance, the properties of the membrane, and the presence of enhancers that facilitate deeper penetration.

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community Does melatonin dissolve in isopropyl alcohol

in Technology 7 upvotes 1 year ago

The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.

community Peptides that Stop Hair Loss? | In-depth Literature Review Video

in Research/Science 74 upvotes 5 months ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

community Fats on your Head to Stop Hair Loss?

in Research/Science 142 upvotes 10 months ago

The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

community Some interesting studies I've found. Peppermint oil at 3% works 2x as well as rogaine.

in Research/Science 17 upvotes 2 years ago

Peppermint oil at 3% was found to improve hair growth more effectively than Minoxidil. The user is also using a topical caffeine hair growth oil and making their own peppermint solution to combat hair thinning.

community Homemade Topical Finasteride Formula?

in Treatment 6 upvotes 2 years ago

User wants to make homemade topical finasteride to minimize side effects and asks about using glycerin, stirring time, storage, and alternative solvents. Another user's comment is unclear.

community A meta analysis of 18 popular hair loss treatments. An 2022 guide on efficacy. From finasteride and minoxidil to caffeine shampoo, saw palmetto and biotin. 96 Scientific References included.

in Research/Science 101 upvotes 2 years ago

Most hair loss treatments are ineffective; only finasteride, dutasteride, and minoxidil show effectiveness.

community What are your thoughts on Redensyl? 85% success rate?!

in Treatment 6 upvotes 2 years ago

Hair loss discussion mentions Redensyl with 85% success rate and visible regrowth. Users skeptical, prefer Minoxidil, Finasteride, and RU58841.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Is it possible that dutasteride won’t make you depressedd if finasteride did?

in Chat 16 upvotes 8 months ago

The conversation discusses whether dutasteride might cause less depression than finasteride for hair loss treatment, with some users suggesting it could due to different mechanisms of action or molecular size, while others express skepticism or share personal experiences with these medications.

community Topical Dutasteride. Does it work?

in Finasteride/Dutasteride 13 upvotes 6 months ago

Topical dutasteride may be effective for hair loss by staying in the scalp and minimizing bloodstream absorption, potentially improving hair results and reducing side effects. The user seeks advice on its effectiveness.

community Is there a topical androgen receptor blocker so we don't have to fuck with the enzyme and destroy our allopregnanolone, but go and hit the end target straight?

in Treatment 45 upvotes 6 months ago

The conversation discusses topical androgen receptor blockers for hair loss, mentioning Clascoterone, Pyrilutamide, GT20029, and RU58841. Ketoconazole's effectiveness and application methods are also debated.

community Why nobody uses 0.25% (2.5mg/ml)?

in Treatment 66 upvotes 11 months ago

The conversation is about the effectiveness of 0.25% topical finasteride compared to other concentrations and forms. Users discuss its potential for better scalp DHT reduction and fewer side effects, with some preferring topical over oral treatments.

community Anybody on here from Germany who can talk to us about alfatradiol (Avicis, Avixis, Ell-Cranell Alpha and Pantostin)? Availability, public perception, etc?

in Treatment 6 upvotes 3 years ago

Hair loss treatments discussed include Minoxidil, Finasteride, and RU58841. A user asks about alfatradiol's availability, public perception, and usage in Germany.

community Are a lot of men already losing their hair at 25?

in Chat 153 upvotes 1 year ago

The conversation discusses the perception of increased hair loss among young men, with some attributing it to heightened awareness or environmental factors. Various treatments are mentioned, including Minoxidil, Finasteride, microneedling, scalp massages, and future hair transplant methods.

community Most hair transplants are obvious

in Transplants 260 upvotes 1 year ago

The conversation is about hair transplants and the perception that they often look unnatural, especially in the first few rows of hair. There is a debate about whether it's better to choose a cheaper clinic in Turkey or a more expensive one in the USA, with some arguing that experience and skill matter more than cost.

community Progression blindness? 4 months Spironoloctone 50mg twice a day

in Progress Pictures 102 upvotes 7 months ago

User shared progress on hair regrowth after 4 months of Spironolactone and iron infusions for Androgenic Alopecia. They see some improvement but struggle with perception; others note significant improvement.

community The worst part of balding is its harder to maintain a balding head

in Shaved/buzzed 327 upvotes 8 months ago

The conversation discusses the challenges of maintaining a balding head, with some preferring to shave regularly and others choosing to embrace their hair loss. Specific treatments or concerns about hair transplants and societal perceptions of balding are also mentioned.

community Anyone else’s loved ones just blatantly gaslight you over your hair ?

in Finasteride/Dutasteride 196 upvotes 1 year ago

User discusses resentment towards people who dismissed their hair loss concerns and continued to do so even after a specialist confirmed it. Others share similar experiences and discuss the impact of hair loss on self-esteem and societal perceptions.

community Having hair loss has completely changed the way I look at other men

in Chat 99 upvotes 1 year ago

A 22-year-old man shared his experience with hair loss, which began at age 20, and his treatment with finasteride and oral minoxidil, planning to add microneedling. Since experiencing hair loss, he has changed his perspective and now notices other men's hair loss more, viewing them positively, and others in the conversation relate to this shift in perception.

community Jordan Peterson got a sick hair transplant!

in Transplants 1078 upvotes 10 months ago

The conversation is about Jordan Peterson allegedly getting a hair transplant, with various users mocking his way of speaking and debating the ethics of him potentially hiding the procedure. Some users discuss the natural look of the transplant and the implications of getting one at an older age.

community Bald and happy guys, sound off!

14 upvotes 10 years ago

A user shares their positive experience of embracing baldness, noting increased attractiveness and dating success after shaving their head. They encourage others to consider going bald instead of relying on medications like Minoxidil, finasteride, or RU58841.

community I don't care if it's thin, I'm keeping it long. 2 yr HT, 1 yr Fin

in Progress Pictures 291 upvotes 2 months ago

OP underwent a hair transplant (HT) and has been using finasteride for one year. Despite having thin hair, OP is happy with the results and feels more confident.

community In my opinion baldness is more prevalent now and it's being ignored..

in Chat 236 upvotes 1 year ago

The conversation is about the prevalence of baldness among young men and the potential factors contributing to it. Specific treatments mentioned include minoxidil and finasteride.

community If a treatment is approved in China (say pyrilutamide or GT20029) would we be able to obtain it if we lived in a different country where it isn’t approved?

in Chat 41 upvotes 1 year ago

Obtaining treatments for hair loss that are not approved in one's own country, such as pyrilutamide or GT20029. It was suggested to use a middleman to get it, but there is the risk of getting low quality or fake products.

community 80 days difference, 1mg fin 3x week, 5% minox 1x daily, 1x week 1.5mm dermaroll, 2x week 2% ketoconazole shampoo.

in Progress Pictures 163 upvotes 4 years ago

A user's progress with hair loss treatments, including Finasteride, Minoxidil, dermarolling and ketoconazole shampoo; showing results of going from bald to having some hair growth. Replies include encouragement, admiration, and disappointment at not seeing similar results.

community He used Dutasteride for 20 years. Interview

in Treatment 109 upvotes 1 month ago

Dutasteride has been used for 20 years with some hair thickness improvement but no dramatic regrowth. The user also experimented with minoxidil, tretinoin, and peptides like BPC 157 for potential benefits in hair density and quality.

community 1 year results finasteride and minoxidil once daily nothing else

in Update 850 upvotes 1 month ago

The user experienced significant hair regrowth after one year of using finasteride, minoxidil, and Nizoral shampoo, with no side effects reported. They noted improved social interactions and emphasized the importance of consistency in treatment.

community My hair loss journey, natural DHT blocker first then Finasteride 1mg every day.

in Progress Pictures 153 upvotes 2 months ago

The user experienced hair regrowth and stopped hair loss using a natural DHT blocker and later finasteride, despite initial side effects. They plan to add topical minoxidil to address remaining thin spots.

community All US hair loss suffers. Do yourself a favor and get a Costco membership.

in Finasteride/Dutasteride 864 upvotes 2 months ago

Costco offers affordable prices for hair loss treatments like finasteride, dutasteride, and minoxidil. Users discuss prescription options and compare prices with services like Mark Cuban's Cost Plus Drugs and Amazon's RxPass.

community 10 months Minoxidil 2.5mg and 8 months Dutasteride 0.5mg - Before/After

in Progress Pictures 661 upvotes 3 months ago

A 29-year-old man used oral Minoxidil and Dutasteride for hair loss, seeing significant regrowth, especially in the crown area, but plans a hair transplant for the temples. Users suggest waiting longer before a hair transplant and trying additional treatments like microneedling and topical Minoxidil.