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GlossaryOff-label Use (Off-label Treatment)

prescribing medication for an unapproved condition or dosage

Off-label use refers to the practice of prescribing a medication for a purpose that has not been officially approved by regulatory agencies like the FDA. This can include using the drug to treat a different condition, in a different dosage, or in a different patient population than what is specified in the approved labeling. While off-label use is legal and can be based on sound medical evidence, it often requires careful consideration and professional judgment.

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community We are in September and heard nothing from the HMI-115 trial

Ambitious-Abroad-707 in Technology 1 upvotes 1 year ago

The user is frustrated about not hearing any updates on the HMI-115 trial for hair loss. They are questioning if there will be any updates in the future.

community Why do most people on Reddit prefer finasteride over dutasteride?

in Treatment 100 upvotes 3 weeks ago

Finasteride is favored for hair loss due to FDA approval, accessibility, and manageable side effects. Dutasteride, though more effective in reducing DHT, is used off-label and may have more side effects.

community 2 months results: Dut 0.5mg / Oral min 2.5mg / Dut+PRP mesotherapy / microneedling

salsasanluis in Progress Pictures 84 upvotes 2 years ago

User's 2-month hair loss treatment includes Dut 0.5mg, oral min 2.5mg, Dut+PRP mesotherapy, microneedling, and other products. Dermatologist increased min dose to 5mg, expecting better results at 6-month mark.

community COMPLETE OVERVIEW of the Treatment of androgenetic alopecia in men

Honor_Bound 26 upvotes 10 years ago

Male androgenetic alopecia is commonly treated with topical minoxidil and oral finasteride, both requiring continuous use. Other options include hair restoration surgery, dutasteride, light therapy, and camouflaging agents.

community Im on 2.5 mg dutasteride, RU, 15 mg Oral Minoxidil, 300 mg Isoflavones, 1800mg NAC, 1000mg Pumpkin Seed Oil, NAD+ and Vipelin

Alumno999 in Finasteride/Dutasteride 21 upvotes 2 years ago

The user improved their hair loss from a Norwood scale 2.5/3 to 1.5/2 using treatments including 2.5 mg dutasteride, RU58841, 15 mg oral minoxidil, isoflavones, NAC, pumpkin seed oil, NAD+, and Vipelin, but still experiences temple recession. Other users expressed concern over the high dosages of oral minoxidil and dutasteride.

community Starting to doubt how effective oral minoxidil is. Loniten / Loxidil Forte

CelebrationOk5060 in Minoxidil 5 upvotes 2 years ago

User doubts oral minoxidil's effectiveness after a month of use and shedding. Few people provide photo evidence of success, and some combine it with other treatments, making it hard to determine its effectiveness alone.

community i got more results 1 month 5 mg oral minoxidil and 1 mg dutasteride then i did 6 months on finasteride and topical minoxidil

No-Simple5403 in Finasteride/Dutasteride 49 upvotes 11 months ago

A user reported better hair regrowth with 5 mg oral minoxidil and 1 mg dutasteride than with finasteride and topical minoxidil, calling topical minoxidil a scam. Replies varied, with some defending topical minoxidil, questioning the user's application method, and suggesting that previous treatments might be contributing to the observed results.

community 15 Week Update of Oral Consumption of Topical Minoxidil. 3 drops Keeps 5% (3.75mg) 2x per day with comparison.

CumShotDiva in Update 2 years ago

CumShotDiva's update on using topical minoxidil orally in an attempt to regrow hair, which has been met with both support and criticism from other users. The conversation includes discussion of possible side effects and the efficacy of this approach.

community Any success stories switching from finasteride to dutasteride?

ExConsultant22 in Finasteride/Dutasteride 36 upvotes 1 year ago

Switching from finasteride to dutasteride for treating hair loss, with reports of improved regrowth and little to no side effects.

community FINASTRIDE and switch to DUTASTRIDE, my experience

x3nima in Progress Pictures 143 upvotes 5 months ago

The user shared their experience with Finasteride and Dutasteride for hair loss. They initially had success with Finasteride but switched to Dutasteride after experiencing shedding, which continued, and are now considering a hair transplant.

community New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase

longdongsilver696 in Research/Science 120 upvotes 8 months ago

Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Microneedling with Topical solution of Min, Dut, and Latanoprost

SuspiciousPickle9843 in Treatment 2 upvotes 1 year ago

A user is considering microneedling to enhance absorption of a prescribed topical hair loss treatment containing Minoxidil, Dutasteride, and Latanoprost, while already taking oral Minoxidil and Dutasteride. They seek advice on the effectiveness and safety of combining these treatments, especially due to the cost and their desire to maximize results.

community Just under 3 mos of topical min/fin 1x/daily, 0.5mm dermarolling daily (before application), and 2% ketoconazole shampoo 3x/week

indiethrows in Progress Pictures 75 upvotes 1 year ago

The conversation discusses hair loss treatment using daily topical minoxidil and finasteride, daily 0.5mm dermarolling before application, and 2% ketoconazole shampoo three times a week. Users believe dermarolling enhances the absorption of the treatments and expect significant improvements over time.

community Any updates on verteporfin or FAK inhibitors regarding donor area hair regeneration? or, when can we expect updates?

Worldly-Type5107 in Technology 10 upvotes 2 years ago

Verteporfin and FAK inhibitors being looked at as potential treatments for hair regeneration, with updates on the unofficial off-label human trial being discussed.

community switched from topical to oral minoxidil (topical mixed with water) 3 months ago and aside from being much easier i’ve also had much more density overall. My results aren’t even finished yet!

Frosty_Wedding8706 in Progress Pictures 2 years ago

This user discussed using oral minoxidil as a hair loss treatment, and was cautioned against mixing topical minoxidil with water and drinking it due to potential side effects and risks. Other users shared their concerns about the dangers of self-prescribing medications without consulting a doctor.

community No, Finasteride as a treatment for MPB was not an "accident"

ViscountOfLemongrab in Research/Science 105 upvotes 3 years ago

Finasteride was intentionally developed to treat BPH and later approved for male pattern baldness (MPB) due to its 5AR inhibition effects. The delay in MPB approval was due to concerns about off-label use for female hirsutism and the prioritization of treating a more debilitating condition.

community Beeezula off label (winlevi compounded)

rafacelina in Treatment 6 upvotes 3 years ago

User seeks availability of Breezula and its delayed trials. Asks for success with similar topical antiandrogens like fluridil.

community Why don’t people just just DUT instead of FIN?

Legitimate_Touch1992 in Finasteride/Dutasteride 48 upvotes 11 months ago

The conversation discusses the use of dutasteride (DUT) versus finasteride (FIN) for hair loss treatment, with some users preferring DUT for its effectiveness while others choose FIN due to its approval status, better long-term data, and lower risk of side effects. Users share personal experiences with both medications, including side effects and effectiveness.

community 0.5mg Dutasteride promotes more “regrowth” than 5mg oral Minoxidil

Villanellat in Research/Science 117 upvotes 1 year ago

Dutasteride promotes more hair regrowth than Minoxidil. Users discuss combining treatments for better results and share personal experiences with side effects.

community How long still for CB-03-01? (breezula)

kennymi in Question 6 upvotes 5 years ago

The conversation is about the release timeline for clinical trial results and the availability of Breezula, a hair loss treatment. The user is not comfortable buying it as a research drug from China.

community 4 months worth of progress! Seeing some results!

Gayninja30_byrd in Progress Pictures 57 upvotes 7 months ago

User shared 4 months of hair loss progress using finasteride and minoxidil, noting improved scalp health with the right shampoo. Encouragement from others includes success stories with similar treatments.

community Why is there more "fear" around on finasteride than around dutasteride

Illustrious-Tie3450 in Chat 18 upvotes 1 year ago

The conversation is about the comparison between finasteride and dutasteride for hair loss treatment. The conclusion is that there is more fear around finasteride due to its higher prevalence and being the first line of defense, while dutasteride is less commonly prescribed and used by those who have already tried finasteride without side effects.

community Guide: How to EASILY get prescription oral minoxidil

Throw_Away24240 in Minoxidil 20 upvotes 2 years ago

The conversation provides a six-step guide on how to get a prescription for oral minoxidil (OM) for hair loss by finding a supportive dermatologist, even if they are not local, and preparing a case for its use during a virtual consultation. The guide emphasizes the importance of research, insurance considerations, and the potential for initial hair shedding with OM treatment.

community Thoughts on Hims Fin+Min all in one chews

Tiny-Strain-6400 in Finasteride/Dutasteride 197 upvotes 1 year ago

Users discussed the convenience and effectiveness of Hims Fin+Min chewable tablets for hair loss. Some believe it's overpriced compared to traditional oral finasteride and minoxidil, while others find it more convenient and potentially more effective.

community Verteporfin Update Dr Barghouthi (prevents scars, potential regrowth)

jsmith78433 in Update 23 upvotes 1 year ago

The potential of using Verteporfin to prevent hair loss scars and possible regrowth, with two doctors currently testing it, although the price of a 15mg bottle is expensive.

community 4 months Oral Minoxidil 1.25 mg Daily (33 M)

ediblediety in Progress Pictures 520 upvotes 2 years ago

This user, "ediblediety", has been taking oral minoxidil (1.25 mg daily), keto shampoo and occasional derm-rolling for 4 months to treat their hair loss, and they have experienced a shedding phase after the first few weeks of use. They report improvements in the thickness of their facial and body hair, but note that this may be daunting to women.

community Got prescribed Dutasteride today

BlueMoonSurface in Treatment 13 upvotes 11 months ago

The conversation is about someone being prescribed Dutasteride for hair loss. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.

community Peace out ✌🏽 Tressless, I’ve went ahead and just shaved off my hair, I no longer want to deal with everything that comes with Finasteride and other drugs, I’ve made my peace, hope everyone in this Sub gain peace and results 💯

Poetichustler in Finasteride/Dutasteride 420 upvotes 2 years ago

The user's decision to shave their head rather than continue using drugs like finasteride and minoxidil to try and stop hair loss, as well as other suggestions such as scalp micropigmentation.

community The best treatment in the future?

Weird_Dare1816 in Research/Science 6 upvotes 3 years ago

Best future hair loss treatment discussed: verteporfin, kx-826, and GT20029. Verteporfin could potentially end baldness with scarless procedures.

community About Verteporfin but not about hair

Neither_Dependent_24 in Technology 17 upvotes 1 year ago

Verteporfin treatment shows promise for hair regeneration and reducing scar tissue in hair transplants. Some users plan to try verteporfin with hair transplants, and it may also be combined with PRP in future experiments.