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Did you mean Nuclear factor erythroid 2-related factor 2?

GlossaryNuclear factor erythroid 2-related factor 2

regulates antioxidant proteins to protect cells from oxidative stress

Nuclear factor erythroid 2-related factor 2 (Nrf2) is a protein that plays a crucial role in cellular defense against oxidative stress by regulating the expression of antioxidant proteins. It helps protect cells from damage caused by free radicals and other reactive molecules, which is important for maintaining healthy hair and preventing conditions like alopecia.

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community How all hormones affect our hair follicles. Not just DHT. Take a look at this paper. Prolactin, melatonin, cortisol, progesterone, testosterone and more

in Research/Science 126 upvotes 2 years ago

The conversation discusses various factors affecting hair loss, not just DHT, and mentions treatments like Minoxidil, finasteride, and melatonin. Some users report personal experiences with these treatments and hormone tests, while others speculate on the role of hormones like prolactin and cortisol in hair loss.

community New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase

in Research/Science 122 upvotes 6 months ago

Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Trestolone (MENT) as a nuclear treatment

in Treatment 99 upvotes 2 years ago

Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.

community Almost 90 days. The hair gods taketh and now giveth.

in Progress Pictures 721 upvotes 1 year ago

User "mynameisbogus" shares hair regrowth progress after 90 days using Dutasteride, oral and topical Minoxidil, RU58841, dermarolling, and Keto shampoo. Others in the conversation praise the impressive results and discuss their own experiences with hair loss treatments.

community Changed my protocol to 5mg’s Oral Minox & 2.5mg’s Dutasteride daily. Finally started making gains. 2 month difference.

in Progress Pictures 273 upvotes 1 month ago

The user changed their hair loss treatment to 5mg oral Minoxidil and 2.5mg Dutasteride daily, resulting in significant hair regrowth over two months. They also used Nizoral 2% Ketoconazole shampoo to improve scalp health.

community Goodbye y'all, it's been a journey but have accepted where I'm at

in Update 219 upvotes 1 year ago

The conclusion of this conversation about hair loss is that the user, y00sh420, tried various treatments including a $700 lllt helmet, topical minoxidil and finasteride, spectraDNC, and micro needling, but did not achieve the desired results. They have decided to stop trying until a cure for male pattern baldness is found. Other users expressed different opinions on hair loss treatments.

community Added RU58841 and having almost instant results

in Treatment 31 upvotes 1 year ago

User added RU58841 to their hair loss treatment and experienced quick results. Others also reported positive effects, but one user experienced chest pains as a side effect.

community Anyone using Peppermint oil/ similar oils and seeing growth?

in Research/Science 6 upvotes 5 months ago

Peppermint oil may be beneficial for hair growth, potentially outperforming minoxidil. Users discuss its effectiveness compared to other treatments like finasteride and RU58841.

community Lion Mane Part 2: Microneedling with Topicals, beneficial compounds, maybe?

in Microneedling 1 upvotes 6 months ago

The conversation discusses microneedling techniques and the use of Minoxidil, copper peptides, EGF, FGF, ceramides, and hydration serums to enhance hair growth. It explores optimizing scalp conditions and the potential benefits of various compounds in conjunction with microneedling.

community Can you guys look at my stack and tell me why I'm not yet in regrowth city?

in Treatment 6 upvotes 10 months ago

The user has been treating hair loss for 2.5 years using finasteride, dutasteride, oral and topical minoxidil with tretinoin, and microneedling, but is experiencing shedding and is unsure if further improvement is possible. Another person shared a similar experience with no gains despite similar treatments.

community Impressed by the progress but think it’s time to go for the transplant?

in Progress Pictures 288 upvotes 9 months ago

The user started taking 2.5mg minoxidil tablets daily and reduced their finasteride dose to 0.5mg due to side effects. They are considering a hair transplant but are unsure if they should proceed now or wait after seeing the effects of the reduced finasteride dosage.

community A Nuanced Look at Microdosing Topical Finasteride

in Finasteride/Dutasteride 85 upvotes 11 months ago

The conversation discusses using a low dose of topical finasteride to achieve hair benefits with minimal systemic exposure. Users share experiences and opinions on dosing, systemic buildup, and side effects of both topical and oral finasteride.

community Almost 3 months | Topical Min (5%), 1 mg Fin, Microneedling, Biotin + Vitamin D Supplement

in Progress Pictures 600 upvotes 1 year ago

The conversation discusses a successful hair regrowth treatment involving topical Minoxidil (5%), 1 mg Finasteride, Microneedling, and Biotin + Vitamin D supplements. The user shares their routine and receives positive feedback on the significant progress made in just three months.

community NW 2 -> NW 1,5 15Mg oral Minoxidil (💀) + Dut 0,5mg 12 Months

in Progress Pictures 77 upvotes 1 year ago

The user, Albertgejmr, is happy with their progress in treating hair loss using 15mg oral minoxidil and 0.5mg Dutasteride. Some users express concern about the high dosage and potential side effects.

community First year progress: oral fin/topical min

in Progress Pictures 408 upvotes 1 year ago

Progress in hair loss recovery over the course of one year, using oral finasteride and topical minoxidil. Suggestions were made to try topical finasteride and minoxidil with microneedling, and other factors such as stress, iron, nutrition discussed.

community 18->24 six years of Fin and Minox…. I guess we can’t all be winners 😭

in Progress Pictures 572 upvotes 2 years ago

A user named "EgyptStar81" who has been dealing with hair loss since age 15 due to genetics, chemotherapy and finasteride/minoxidil treatment. Possible solutions such as dutasteride, oral minoxidil, hair transplants and extensions were suggested.

community Does finasteride/dutasteride reverse aging?

in Chat 45 upvotes 1 month ago

Finasteride and dutasteride can improve skin texture and reduce acne by lowering DHT but do not reverse aging. They may enhance skin and hair health for some, but can also cause side effects like dry skin and sexual dysfunction.

community How does dutasteride regrowth work?

in Finasteride/Dutasteride 6 upvotes 6 months ago

A 25-year-old man with hair loss from bleach damage is using oral minoxidil and considering adding Dutasteride for better regrowth and prevention. He seeks advice on Dutasteride's effectiveness and potential benefits over finasteride, and is also curious about RU58841.

community Does whey protein and creatine aggravate hair loss?

in Research/Science 82 upvotes 11 months ago

The conversation discusses whether whey protein and creatine worsen hair loss. Some users report hair loss with creatine use, while others do not; opinions on whey protein's effects are mixed. Treatments mentioned include PRP, minoxidil, and finasteride.

community Here are the results from my journey! I used saw palmetto tablets instead of Finasteride(I was afraid of using it), 5% Minoxidil spray and Derma Pen once a week 1.5mm.

in Progress Pictures 306 upvotes 11 months ago

The user shared their positive hair regrowth experience using saw palmetto tablets, 5% minoxidil spray, and a Derma Pen. The conversation debates the effectiveness of saw palmetto versus finasteride, with some advocating for natural treatments and others emphasizing the proven results of finasteride and minoxidil, often in combination with microneedling.

community Study shows further evidence that finasteride and dutasteride take 12-18 months or more to show significant results. Do NOT give up early

in Finasteride/Dutasteride 247 upvotes 1 year ago

The conversation discusses the effectiveness of finasteride and dutasteride in treating hair loss, emphasizing that significant results often take 12-18 months or more. Dutasteride is generally considered superior, with similar or fewer side effects than finasteride, but patience is required for noticeable improvement.

community Why is it barely impossible to find balding South Korean men

in Research/Science 244 upvotes 1 year ago

The post discusses the rarity of baldness among South Korean men. Users suggest this could be due to early treatment, high beauty standards, accessibility of healthcare, and genetics. Treatments like finasteride and dutasteride are commonly used, and hair transplants are also popular.

community DHT Itch is real. The connection between Acne and Male Pattern Baldness shows this

in Research/Science 64 upvotes 1 year ago

The conversation discusses the link between seborrheic dermatitis, acne, and male pattern baldness, suggesting that DHT may cause both skin conditions and hair loss. Treatments mentioned include RU58841, finasteride, dutasteride, minoxidil, Nizoral shampoo, and other topical anti-androgens.

community Diffuse thinning is so brutal.

in Styling 72 upvotes 1 year ago

A 25-year-old with AGA experienced hair thinning and dandruff, stabilized with topical finasteride and minoxidil but saw minimal regrowth. They seek advice on styling and consider oral minoxidil and microneedling for denser hair.

community My story (22m, fin, min, niz, RU, dut –> part frontal hair system)

in Finasteride/Dutasteride 19 upvotes 1 year ago

User "hairplsrn" shares their hair loss journey, trying various treatments like finasteride, minoxidil, and dutasteride, but experiencing worsening hair loss. They decide to get a partial frontal hair system and continue medication, while others offer support and advice on staying on medication and focusing on overall confidence.

community New drug for hair loss announced by Amplifica

in Research/Science 161 upvotes 1 year ago

Amplifica starting clinical trials for new hair loss drug. SCUBE3 protein discovered, stimulates hair growth, could be alternative to Minoxidil and Finasteride.

community Completely defeated after trying so hard with topical finasteride.

in Finasteride/Dutasteride 24 upvotes 1 year ago

A user who has tried multiple treatments for hair loss, including oral and topical finasteride and liposomal finasteride, but experienced severe side effects in each case; the user is considering trying RU58841 or aromatise inhibitors as alternatives.

community Brutal shed at 5 months

in Minoxidil 6 upvotes 3 years ago

User experienced significant hair regrowth with multiple treatments, but then had a brutal shedding period, losing progress. Others questioned the number of treatments used and potential side effects.

community Why isnt topical fin talked about more?

in Chat 43 upvotes 1 week ago

Topical finasteride is less popular due to inconvenience, cost, and availability, while oral finasteride is favored for ease and safety. Some users experience side effects with topical use, but find it effective with minoxidil, though opinions on its efficacy vary.

community Why is it so hard to select one

in Satire 636 upvotes 1 week ago

Choosing hair loss treatments is challenging due to concerns about side effects from finasteride and minoxidil. Users suggest starting with topical treatments and gradually increasing dosage, while some recommend oral finasteride for its effectiveness despite potential side effects.