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    Did you mean Non-coding RNAs?
    GlossaryNon-coding RNAs

    molecules of RNA that regulate gene expression without making proteins

    Non-coding RNAs (ncRNAs) are molecules of RNA that do not encode proteins but play crucial roles in regulating gene expression and maintaining cellular functions. They include various types such as microRNAs (miRNAs) and long non-coding RNAs (lncRNAs), which can influence processes like cell growth, differentiation, and response to stress, making them important in both normal biology and disease states.

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      community We need to keep these snake oil companies accountable.

      in Treatment  118 upvotes 3 months ago
      Biotin is being misleadingly marketed as a primary treatment for androgenic alopecia, overshadowing more effective treatments like finasteride and minoxidil. There is a call for increased awareness and accountability to prevent misinformation.

      community Why is dht bad for scalp hair but good for hair on the rest of body?

      in Satire  109 upvotes 1 year ago
      The conversation discusses why DHT (dihydrotestosterone) negatively affects scalp hair but promotes growth elsewhere on the body. Various opinions include genetic predispositions, differences in hair follicle reactions to DHT, and the potential role of Omega-3 in reducing inflammation and promoting hair health.

      community How do we only have two treatments to combat hair loss at this point in time?

      in Chat  212 upvotes 1 year ago
      The post discusses frustration over the limited and not always effective treatments for hair loss, mainly Minoxidil and Finasteride. The conversation includes mentions of potential new treatments like GT20029, HMI-115, CosmeRNA, KX-826, and microneedling, but also highlights the challenges of funding and prioritizing research in this area.

      community Quit vaping/smoking = 80% less loss

      in Research/Science  235 upvotes 5 months ago
      Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

      community I find it funny a bunch of us on here are on drugs for hairloss and maintain clean/healthy lives and then there’s these mf’s in the 90’s juiced to the gills with steroids and have better hair than all of us lol

      in Satire  353 upvotes 1 year ago
      The conversation is about the effects of steroids on hair loss. Some users believe that steroids can cause hair loss, while others argue that it depends on individual sensitivity to DHT. There is also discussion about the appearance of balding individuals who use steroids.

      community My Testosterone results before and after Finasteride

      in Update  146 upvotes 3 years ago
      Finasteride significantly increased testosterone levels for the user, with no major side effects except watery semen, which was resolved with zinc supplements. The user's hairline stopped receding and slightly improved.

      community My Current Hairloss Stack (No Finasteride)

      in Update  11 upvotes 1 year ago
      Hair loss treatments, specifically Minoxidil, Fluridil & Alfatradiol, Nizoral, Saw Palmetto, Hairmetto and Microneedling. The user mentioned they have seen a decrease in shedding and improvement in the quality/density of their hair since using this stack, but opted out of trying Finasteride due to potential side effects.

      community What ever happened to pyrilutamide?

      in Technology  48 upvotes 1 year ago
      Pyrilutamide, a potentially effective hair loss treatment; other topical treatments like RU58841 and CB-03-01 that may have fewer side effects than Pyrilutamide; and the Phase 3 clinical trials of Pyrilutamide, which is likely to be approved by the FDA soon.

      community A year of fin+min(23yo), got my life back

      in Progress Pictures  2187 upvotes 1 year ago
      A 23 year old user who has had success with finasteride and minoxidil, regaining their hair after losing it due to male pattern baldness. They also attribute part of the success to lifestyle changes such as eating better, exercising, sleeping well, and reducing smoking.

      community Physician here AMA – 30M oral Fin 1-1.25 mg daily

      in Update  47 upvotes 2 years ago
      Hair loss treatments, specifically the use of finasteride, microneedling and potentially oral minoxidil. People discussed their experiences with finasteride, its effects on sexual behaviors, as well as potential solutions such as tadalafil or using other growth factor signal peptides for hope in curing male pattern baldness.

      community Hold up... CosmeRNA/SAMiRNA is actually coming real soon?

      in Technology  31 upvotes 1 year ago
      A user discovered CosmeRNA, a new hair loss treatment with clinical research backing, set to release soon. The conversation revolves around its potential effectiveness, cost, and how it compares to existing treatments like Minoxidil and Finasteride, with some users expressing hope for a side-effect-free option.

      community hmi115 is coming. Prepare yourselves for what's coming

      in Technology  110 upvotes 1 year ago
      The conversation discusses HMI-115, a potential cure for hair loss. Users share mixed opinions, with some expressing skepticism and others sharing anecdotal evidence of its effectiveness, including photos of significant hair regrowth from a trial participant.

      community Found a winning combo for a non/weak-responder

      in Research/Science  4 upvotes 2 months ago
      A user found a successful hair loss treatment using a combination of finasteride, dutasteride, minoxidil, and RU58841. They plan to switch to a purely topical regimen with finasteride, RU58841, and minoxidil.

      community Rare Non responder to Finasteride, Dutasteride, and oral minoxidil

      in Minoxidil  78 upvotes 6 months ago
      A user did not respond to finasteride, dutasteride, and oral minoxidil for hair loss after four years of treatment and is considering scalp micropigmentation (SMP). Other users suggest the hair loss pattern may indicate alopecia areata and recommend seeing a dermatologist.

      community oral minoxidil is coming in clutch fr

      in Satire  641 upvotes 2 years ago
      . This conversation is a satire post about a user who appears to have an abundance of hair, with other users commenting and asking questions about the treatments they use for their hair loss. Treatments discussed include minoxidil and finasteride.

      community Anyone excited for CosmeRNA coming this month?

      in Product  171 upvotes 1 year ago
      CosmeRNA, a new hair loss treatment, is expected to release soon and may become part of the "big three" treatments alongside finasteride and minoxidil. It works differently from finasteride by targeting androgen receptors in hair follicles, potentially offering fewer side effects.

      community My hair is coming back, in as little as 11 days, is that normal?

      in Chat  6 upvotes 4 years ago
      A user reports significant hair regrowth in 11 days using 1mg finasteride daily and 2ml minoxidil daily, and questions if they can maintain their hair with just minoxidil and a good shampoo. They express concern about potential side effects of finasteride.

      community 1 month Pyrilutamide. A non responders story to everything.

      in Research/Science  218 upvotes 1 year ago
      My hairline, I am only 23. This conversation is about a user's experience with treatments for androgenic alopecia, including finasteride, dutasteride, RU, minoxidil, progesterone, melatonin, LLLT, oral minoxidil, and Pyrilutamide. They have tried many treatments over the course of two years without seeing much success, and they are considering getting a hair system as a last resort.

      community 35 MtF | 16 Months | Minoxidil + Dutasteride + Microneedling + Exosomes. Note that since I'm early in my transition (and I was coming from a bald state), I still have short hair. Very few MtF progress pictures here, I figure this might help some of you.

      in Transgender  128 upvotes 9 months ago
      A 35-year-old transitioning female (MtF) shared her hair regrowth journey using Minoxidil, Dutasteride, Microneedling, and Exosomes, starting from a bald state. Commenters discussed the impressive results, skin care routine, and the effects of estrogen on hair and skin.

      community maybe some of you need to hear this

      in Chat  326 upvotes 2 years ago
      Coping with hair loss, the effects of finasteride and minoxidil, and strategies for maintaining self-esteem while experiencing hair loss.

      community What are these spots on my scalp

      in Treatment  51 upvotes 2 months ago
      A user noticed non-itchy, non-bleeding spots on their scalp while experiencing hair loss. Replies suggest the spots are likely sunspots or liver spots and recommend seeing a dermatologist; hair loss is attributed to male pattern baldness.

      community Losing hope. Might have to buzz.

      in Chat  37 upvotes 1 year ago
      The conversation is about coping with hair loss and includes advice on improving overall appearance and confidence. Specific hair loss treatments mentioned are not discussed.

      community Is flying with Fluridil a problem?

      in Treatment  6 upvotes 2 years ago
      The post is about the potential legal trouble of bringing a four-month supply of fluridil, a hair loss treatment, into non-Western countries.

      community So we’re just ok with taking a research chemical now?

      in Treatment  175 upvotes 3 years ago
      The conversation discusses the use of RU58841, a non-FDA approved research chemical for hair loss, with mixed opinions on its safety and effectiveness. Some users are willing to try it as a last resort after other treatments like Minoxidil and Finasteride failed, while others express concerns about potential long-term side effects and lack of official research.

      community Diagnosed with MPB at 16 (Male)

      in Treatment  52 upvotes 4 months ago
      A 16-year-old diagnosed with male pattern baldness (MPB) was prescribed hair vitamins, vitamin D, a non-ketoconazole shampoo, and redenysl + serum, with a suggestion for GFC or IHRF treatments. Some users recommended minoxidil, ketoconazole, and derma stamping, while others advised against certain treatments until the age of 18.

      community 5% Minoxidil after 4 months - started with twice a day but went down to once because I kept forgetting in the morning. Really happy with how it is going!

      in Progress Pictures  438 upvotes 1 year ago
      The conclusion of the conversation is that the user started using 5% Minoxidil for hair loss and is happy with the progress. They also mentioned being trans and coming off testosterone, which they believe will help prevent further hair loss. Some users suggested using finasteride as well.

      community This is the best time in human history to be fighting hair loss

      in Treatment  194 upvotes 2 years ago
      This conversation discusses the advancements in treatments for hair loss, including finasteride, dutasteride, minoxidil and new promising treatments such as pyrilutamide and verteporfin. Other treatments discussed were taking minoxidil orally, tretinoin to turn non-responders into responders and microneedling to further boost growth.
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