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GlossaryMice (Mouse)

small rodents often used in biological and medical research

Mice, also known as murine rodents, are small mammals commonly used in scientific research due to their genetic, biological, and behavioral similarities to humans. They are particularly valuable in studies related to hair and alopecia because their genetic makeup can be easily manipulated to model human diseases, allowing researchers to investigate the underlying mechanisms and potential treatments.

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community Hair Loss Treatment Iceberg Chart

in Satire 1381 upvotes 2 years ago

Hair loss treatments discussed include Minoxidil, Finasteride, RU58841, ass hair transplant, topical Viagra, castration, and transitioning to female. A user mentions an experimental drug called M4U-5 (Mousteride) that turns you into a mouse.

community Anyone have an opinion on this: Promotion of Hair Growth by Rosmarinus officinalis Leaf Extract. They aimed to find out if Rosemary Oil is able to inhibit activity of 5α-Reductase.

in Research/Science 1 upvotes 1 year ago

Rosemary Oil may inhibit the activity of 5α-Reductase, potentially promoting hair growth. Specific treatments discussed include Minoxidil, Finasteride, and RU58841.

community Study: Peppermint oil more effective than minoxidil, thoughts?

in Research/Science 14 upvotes 1 year ago

The conversation discusses a claim that peppermint oil is more effective than minoxidil for hair loss, with one user mentioning using a mix of peppermint and rosemary oils as a treatment. Some users are skeptical, while others show interest in the potential of peppermint oil.

community Is anyone buying this comb over?

in Styling 310 upvotes 1 year ago

User has diffuse thinning crown and uses combover with hair spray. Oral minoxidil showed amazing results for another user.

community Rapamycin for Longevity 2022 - Hair pigmentation and regeneration in mice

in Chat 6 upvotes 2 years ago

The conversation is about the potential benefits of Rapamycin for hair pigmentation and regeneration, based on effects observed in mice. The original poster is seeking personal experiences from others using Rapamycin for longevity.

community Prolactin’s role in antitumor activity of the immune system – a safety concern for HMI-115?

in Research/Science 3 upvotes 1 year ago

Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. Prolactin's role in immune system's antitumor activity raises safety concerns for HMI-115.

community Study published yesterday : "Brassica oleracea extract, glucosinlates and sulforaphane promote hair growth in vitro and Ex vivo"

in Research/Science 32 upvotes 3 years ago

The conversation discusses hair loss treatments, specifically Brassica oleracea extract, glucosinolates, and sulforaphane, and their potential to promote hair growth. Users also mention minoxidil and finasteride as existing treatments.

community Is 2-deoxy-D-ribose (2dDR) good for human hair?

in Research/Science 9 upvotes 2 months ago

Topical 2-deoxy-D-ribose (2dDR) regrows hair in mice almost as well as 2% Minoxidil. However, 2dDR may contribute to oxidative stress and hair loss due to the formation of advanced glycation end products (AGEs).

community New study: Vitamin D counteracts DHT in mice and in human hair organ culture and hair cells

in Research/Science 125 upvotes 1 week ago

community Scientists have found that a naturally occurring sugar in humans and animals could be used as a topical treatment for male pattern baldness | In the study, mice received 2dDR-SA gel for 21 days, resulting in greater number of blood vessels and an increase in hair follicle length and denseness

in Research/Science 634 upvotes 4 months ago

Scientists discovered a sugar gel, 2dDR-SA, that increased hair growth in mice. Users discussed its potential, comparing it to other treatments like Minoxidil and finasteride.

community [Research] RU-58841/Pyrilutamide and impacts on male fertility

in Research/Science 6 upvotes 1 year ago

The drugs RU-58841, Pyrilutamide (KX-826), Apalutamide, Enzalutamide, and Darolutamide, which are nonsteroidal antiandrogens (NSAA), potentially impacting male fertility. Pyrilutamide, similar to Enzalutamide, may have reversible effects on fertility.

community New drug for hair loss announced by Amplifica

in Research/Science 161 upvotes 1 year ago

Amplifica starting clinical trials for new hair loss drug. SCUBE3 protein discovered, stimulates hair growth, could be alternative to Minoxidil and Finasteride.

community Selling a premixed KY19382 solution

in Research/Science 8 upvotes 2 years ago

The conversation discusses the sale of a premixed KY19382 solution for research purposes, highlighting previous unsuccessful group buys and the formulation process. Prices and purchasing options for KY19382 solutions and powder are provided.

community Found it. Sulforaphane, a phytochemical in broccoli sprouts, promotes hair growth (60% regeneration in mice) by accelerating the degradation of DHT.

112 upvotes 7 years ago

Sulforaphane, found in broccoli sprouts, promotes hair growth by degrading DHT. Users discuss its potential benefits and joke about unconventional application methods.

community IGFBP‐rP1 is a potential therapeutic target in androgenic alopecia

in Research/Science 13 upvotes 3 weeks ago

IGFBP‐rP1 shows potential for treating androgenic alopecia by influencing hair cycle transitions. Increasing IGF-1 levels may have similar effects to Minoxidil and 5-AR inhibitors in reducing hair loss.

community My kid secretly took my avodart what should i do

in Is this regrowth? 42 upvotes 1 month ago

A child accidentally took Avodart, leading to concerns about DHT suppression and its effects. Users humorously discuss potential consequences and treatments like DHT injections and topical solutions.

community Innovative hair loss treatment can restore 90% of lost hair

in Research/Science 887 upvotes 2 months ago

A new hair loss treatment using dermal exosomes can restore up to 90% of lost hair in mice. Users discuss potential human trials and compare it to Minoxidil and Finasteride.

community Do hair follicles ever really "die"? Or does all your front, mid, and crown hair just become vellus?

in Chat 139 upvotes 3 months ago

Hair follicles don't truly die but become severely miniaturized. Treatments like finasteride, dutasteride, and minoxidil can help restore hair by providing nutrients and reducing harmful effects on hair roots.

community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

in Research/Science 14 upvotes 5 months ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.

community Polydopamine Synergizes with Quercetin Nanosystem to Reshape the Perifollicular Microenvironment for Accelerating Hair Regrowth in Androgenetic Alopecia.

in Research/Science 13 upvotes 6 months ago

A quercetin-encapsulated and polydopamine-integrated nanosystem (PDA@QLipo) shows promise for treating androgenetic alopecia by reshaping the perifollicular microenvironment, outperforming minoxidil in hair regeneration. The nanosystem promotes cell proliferation, hair follicle renewal, and recovery by scavenging reactive oxygen species and enhancing neovascularity.

community Stemson Therapeutics Announces Technological Breakthrough in new Hair Growth

in Research/Science 61 upvotes 9 months ago

Stemson Therapeutics announced a breakthrough in hair growth technology using stem cells. Users discussed the potential high cost and skepticism about the treatment's accessibility.

community what is a realistic timeline when does hmi-115 gets released? What are they doing in the non-clinical dev. phase?

in Research/Science 7 upvotes 1 year ago

Hair loss treatments discussed include Minoxidil, Finasteride, and RU58841. HMI-115 release timeline is uncertain, with possible grey market availability in 2024-2025.

community Anything you use without scientific backing, just trusting your gut?

in Research/Science 13 upvotes 1 year ago

The conversation discusses using peppermint oil for hair loss, with one user applying it undiluted to the scalp and another combining it with finasteride and microneedling. Some believe in its effectiveness despite limited scientific evidence, and also mention rosemary oil as potentially beneficial.

community Why Is Only Tressless Talking About Verteporfin? Healing Wounds With Zero Scarring Has Gargantuan Implications For All of Medicine. So What Gives?

in Research/Science 19 upvotes 1 year ago

The potential of verteporfin to heal wounds without scarring; however, despite its promising preclinical trials and coverage from a major media outlet, there is still no official clinical trial result and the drug has only garnered attention from hair loss communities.

community A meta analysis of 18 popular hair loss treatments. An 2022 guide on efficacy. From finasteride and minoxidil to caffeine shampoo, saw palmetto and biotin. 96 Scientific References included.

in Research/Science 101 upvotes 2 years ago

Most hair loss treatments are ineffective; only finasteride, dutasteride, and minoxidil show effectiveness.

community Hair loss treatment rabbit hole [OC]

in Satire 317 upvotes 2 years ago

Hair loss treatments, ranging from topical minoxidil and finasteride to taking hormones such as estradiol or nandrolone, as well as a controversial suggestion of an orchiectomy. A hair system is also mentioned as an alternative solution.

community I could just be fooling myself here but

in Is this regrowth? 120 upvotes 1 month ago

The user is experiencing hair regrowth using a combination of oral finasteride, a minoxidil/finasteride topical spray, and dermarolling. They plan to continue this regimen and may consider adding dutasteride if needed.

community 3 months of fin + min. Will I expect shedding anytime soon?

in Will treatment work for me? 564 upvotes 3 months ago

The user is concerned about potential shedding after three months of using finasteride and minoxidil for hair loss. Replies include comments on the effectiveness and dosage of these treatments.

community Is there any new drug that looks promising ?

in Research/Science 25 upvotes 8 months ago

The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.

community Guys hear me out we might have a breakthrough

in Satire 662 upvotes 9 months ago

The conversation is a satirical discussion about unconventional hair loss treatments, including using mold, butter, and other non-traditional substances, with no real evidence of effectiveness. Some users joke about side effects like erectile dysfunction and weight gain.