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    Glossary Mitochondrial Biogenesis

    process of creating new mitochondria within cells

    Mitochondrial biogenesis is the process by which cells increase their individual mitochondrial mass and copy number to meet increased energy demands. This involves the growth and division of pre-existing mitochondria, regulated by various signaling pathways and transcription factors, such as PGC-1α, which coordinate the expression of nuclear and mitochondrial genes.

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