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GlossaryMicroglia

specialized immune cells in the brain and spinal cord

Microglia are specialized immune cells located in the brain and spinal cord that act as the main form of active immune defense in the central nervous system. They constantly monitor the environment for signs of damage or infection and can engulf and destroy pathogens, clear away dead cells, and release signaling molecules to modulate inflammation and repair processes.

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community How is it that golden era bodybuilders kept their hair while blasting gear while in the modern era most are bald? I’m convinced there’s something in our food and water causing MPB to speed up

in Satire 729 upvotes 1 year ago

The conversation is about the difference in hair loss between bodybuilders in the "Golden Era" and modern bodybuilders. Some users speculate that factors such as the types and doses of steroids used, genetics, diet, microplastics, and overall health may contribute to hair loss. Hair loss prevention medication and transplants are mentioned as potential treatments.

community Shampoo for a thicker appearance

in Advice 21 upvotes 4 years ago

A user recommends a biotin collagen shampoo for making hair appear thicker and feeling nice. Another user mentions using a similar product with argan oil from Walmart.

community 1mg and .5mg finasteride inhibit roughly the same amount of DHT, but have studies ever directly compared the two when just looking at regrowth?

in Finasteride/Dutasteride 12 upvotes 7 months ago

The conversation is about whether taking 0.5mg of finasteride daily is as effective as 1mg for hair regrowth and if there are long-term studies supporting the lower dose. The user is considering the lower dose to save money and reduce concerns about side effects.

community 3 Year Update (26m) (fin, min, micro needling, nizoral)

in Progress Pictures 155 upvotes 2 years ago

Hair loss treatment with finasteride, minoxidil, microneedling, and nizoral shows impressive results after 3 years. Dermatologist recommended starting with finasteride before adding other treatments.

community The Worst Hair Loss Condition You (MAY) have: LPP

in Research/Science 43 upvotes 3 months ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community 9 months progress on fin and min

in Is this regrowth? 384 upvotes 4 months ago

User shared 9 months of progress using 1 mg finasteride and topical minoxidil, showing photos from different stages. Encouragement was given to continue the treatment.

community Is it just me, or when people start having MPB symptoms, every single person you look at you start analyzing their hair? Ik it sounds weird

in Chat 168 upvotes 5 months ago

A user discusses their habit of analyzing others' hair due to their own hair thinning at 18. Another user mentions starting finasteride in 2010 and still having a full head of hair.

community Man fuck The Beatles they lyin

in Satire 211 upvotes 6 months ago

The conversation humorously criticizes The Beatles for having more hair in old age than the user at 20. It includes mentions of finasteride and dutasteride as hair loss treatments.

community 7 months on just topical finasteride (caretopic)

in Progress Pictures 52 upvotes 6 months ago

A user shared their 7-month progress using only topical finasteride for hair loss. They recently started a new, non-FDA treatment and will evaluate its effectiveness in 6 months.

community Let's be clear, does Finasteride stop MPB as long as it's taken?

in Finasteride/Dutasteride 170 upvotes 8 months ago

Finasteride is believed to slow down hair loss significantly, but may not completely stop it for everyone. Effectiveness and duration vary by individual, with some users experiencing positive results for over 10 years, while others see less benefit.

community People call companies stupid for making very high concentration Topical Fin solutions but I think they overlook the fact that the actual absorption rate of finasteride varies greatly

in Finasteride/Dutasteride 13 upvotes 9 months ago

The conversation discusses how the absorption rate of topical finasteride varies and is not equivalent to its oral form, with only a small percentage reaching the scalp. It also mentions that minoxidil in high concentrations is used topically because only a small amount is absorbed.

community 2 months on topical Finasteride, Minoxidil.

in Progress Pictures 37 upvotes 10 months ago

The user started using 0.05% topical finasteride and minoxidil for hair loss treatment on December 15, also incorporating dermarolling and rosemary oil, and is satisfied with the visible improvement in their receding hairline. Another user inquired about where to obtain topical finasteride.

community People who taking melatonin, do you have any grey hairs?

in Research/Science 9 upvotes 1 year ago

The post discusses the theory that melatonin could reverse grey hair by regulating certain enzymes. However, users who have taken melatonin reported no effect on preventing or reversing grey hair.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

in Research/Science 65 upvotes 1 year ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community Is there an improvement? Zinc, biotin, and D3

in Is this regrowth? 7 upvotes 1 year ago

The conversation discusses hair regrowth improvement due to zinc, biotin, and D3 supplements, highlighting that hair loss can result from deficiencies, not just androgenetic alopecia. The user emphasizes that treatments like finasteride are not the only solutions.

community Using Minoxidil without Finasteride

in Minoxidil 1 year ago

The effectiveness of using minoxidil alone as a hair loss treatment, and whether or not finasteride should be taken in addition to the minoxidil. Replies suggest that minoxidil is only effective for a short period of time, and finasteride should be added to the treatment plan.

community Blood results on micro-dosing topical finasteride (DHT Increased!)

in Finasteride/Dutasteride 4 upvotes 1 year ago

The conversation discusses using homemade topical finasteride for hair loss, showing an increase in DHT levels despite treatment. The user applies 0.125mg daily, resulting in 113.4% of previous DHT levels.

community 15 Week Update of Oral Consumption of Topical Minoxidil. 3 drops Keeps 5% (3.75mg) 2x per day with comparison.

in Update 2 years ago

CumShotDiva's update on using topical minoxidil orally in an attempt to regrow hair, which has been met with both support and criticism from other users. The conversation includes discussion of possible side effects and the efficacy of this approach.

community How many guys on here are doing the low dose topical finasteride (solo without minox)?

in Finasteride/Dutasteride 26 upvotes 2 years ago

User discusses using low dose topical finasteride without minoxidil for hair loss. Another user shares their experience with homemade 0.025% finasteride topical, shedding, and microneedling.

community 4 months using finasteride | minoxidil | ketoconazole | dermaroller (update)

in Finasteride/Dutasteride 369 upvotes 3 years ago

User "mo_movic" shared 4-month progress using finasteride, minoxidil, ketoconazole, and dermaroller for hair loss. Others congratulated and discussed their own experiences, with "mo_movic" reducing finasteride dose and using ketoconazole twice a week.

community What would be an ideal diet for promoting health for what's left/regrowth?

in Question 38 upvotes 6 years ago

The conversation discusses an ideal diet for promoting hair health, emphasizing biotin, collagen, vitamins C and E, zinc, selenium, anti-inflammatory foods, and blood circulation. It also mentions using finasteride, minoxidil, and dermarolling for hair regrowth.

community I just made 60x of 5mg minoxidil sugar cubes

in Minoxidil 1319 upvotes 3 weeks ago

A user created oral minoxidil sugar cubes due to lack of prescription access, leading to a humorous discussion about unconventional and potentially unsafe methods of using minoxidil. The conversation highlights the lengths people go to for hair growth.

community just saw my hair under harsh sunlight and devastated..

in Chat 121 upvotes 1 month ago

The conversation discusses hair loss struggles and treatments, including oral minoxidil, oral finasteride, and RU58841. Users share experiences and advice, suggesting options like topical minoxidil, microneedling, hair transplants, and scalp micropigmentation.

community Genetics are so weird and unpredictable

in Minoxidil 118 upvotes 1 month ago

The user experienced male pattern baldness starting at 18, tried finasteride with no success, and switched to dutasteride, which halted hair loss. Minoxidil had no effect for them, while their brother, who didn't use AR inhibitors, maintained a juvenile hairline and successfully grew a beard with minoxidil, highlighting the unpredictable nature of genetics in hair loss and treatment response.

community Reminder: You cannot donate blood if you are taking Fin or Dut

in Finasteride/Dutasteride 720 upvotes 2 months ago

You cannot donate blood if you are taking finasteride or dutasteride due to potential risks to pregnant women. Finasteride has a shorter wait time to donate blood compared to dutasteride, and both oral and topical forms can disqualify you from donating.

community Anyone else realize how many younger guys are balding?

in Chat 262 upvotes 2 months ago

Many younger men are experiencing hair loss due to genetics, diet, stress, and lifestyle changes. Treatments like finasteride and minoxidil are mentioned, with some users noting improvements.

community 5 months of nuking T, 2 months of minoxidil

in Transgender 485 upvotes 3 months ago

The user transitioned from finasteride to Cyproterone and started using Minoxidil, resulting in healthier hair and regrowth. They plan to wean off Minoxidil in a year, depending on regrowth.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Fin isn’t working anymore after 3 years, afraid to switch to dut?

in Finasteride/Dutasteride 27 upvotes 4 months ago

Finasteride stopped working for a user after 3 years, and they are considering switching to dutasteride. Other users suggest trying dutasteride, with some sharing positive experiences and additional treatments like minoxidil and RU58841.

community Everyone is ignoring that plasma finasteride levels are 100x lower with topical compared to oral.

in Research/Science 138 upvotes 5 months ago

Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.