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    GlossaryIonotropic Receptor (Ligand-Gated Ion Channel)

    An ionotropic receptor, also known as a ligand-gated ion channel, is a type of receptor that allows ions to pass through the cell membrane in response to the binding of a chemical messenger, such as a neurotransmitter. When the neurotransmitter binds to the receptor, it causes the channel to open, allowing specific ions like sodium, potassium, or calcium to flow into or out of the cell, which can trigger various cellular responses.

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      community Ligand Chem cease trading Pyrilutamide

      in Product  14 upvotes 1 year ago
      Pyrilutamide, a possible hair loss treatment, ceasing to be traded due to patent laws; and the hope that this indicates it may be a legitimate treatment.

      community Dropping RU , not responding..

      in Treatment  6 upvotes 3 months ago
      The user has been using RU58841 for 6 months without noticeable results and is considering dropping it while continuing oral minoxidil, daily dutasteride, and topical minoxidil. Another user suggests visiting a dermatologist to check for other conditions.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  692 upvotes 3 weeks ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community How does dutasteride regrowth work?

      in Finasteride/Dutasteride  6 upvotes 3 months ago
      A 25-year-old man with hair loss from bleach damage is using oral minoxidil and considering adding Dutasteride for better regrowth and prevention. He seeks advice on Dutasteride's effectiveness and potential benefits over finasteride, and is also curious about RU58841.

      community Fats on your Head to Stop Hair Loss?

      in Research/Science  137 upvotes 6 months ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.