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GlossaryLichen Simplex Chronicus

chronic skin condition causing thickened, itchy patches from repeated scratching

Lichen Simplex Chronicus (LSC), also known as Neurodermatitis, is a skin condition characterized by chronic itching and scratching, leading to thickened, leathery patches of skin. It often results from a cycle where an initial itch causes scratching, which then exacerbates the itch, creating a persistent problem. This condition can be triggered by stress, dry skin, or other underlying skin disorders.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 7 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community C’est terrible - at my wits end

in Female 443 upvotes 1 year ago

A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

community After Years of Treatment, I'm Shaving my Head and Giving Up

in Shaved/buzzed 118 upvotes 4 months ago

After years of using dutasteride and oral minoxidil without success, the individual decided to shave their head and stop treatment. They considered scalp micropigmentation and hair systems but ultimately accepted their hair loss.

community My result with 5month min+micro1m+tretinoin0.0025+nizoral

in Progress Pictures 100 upvotes 1 year ago

The conversation discusses hair loss treatment results after 5 months using Minoxidil, microneedling with a 1mm length every 5 days, Tretinoin (0.0025%), and Nizoral. The user noticed an increase in hair density.

community I [19m] have been on finastride for almost 2 years and I am still receding

in Finasteride/Dutasteride 44 upvotes 1 month ago

A 19-year-old male has been using finasteride and minoxidil for nearly two years but continues to experience hairline recession. He is considering switching to dutasteride and exploring options like hair systems and potential future hair transplants.

community Is hair thinning or loss associated with pain?

in Research/Science 6 upvotes 1 year ago

Hair thinning/loss associated with burning scalp pain. Finasteride helped relieve "DHT itch" for one person.

community Hasson & Wong: Dr Jerry Wong FUT 2877 Grafts. Failed surgery. Possible negligence and illegal behaviour.

in Transplants 492 upvotes 1 year ago

A user who had FUT surgery for 2877 grafts with Dr Jerry Wong of Hasson & Wong that resulted in low growth and an abnormally wide scar, suggesting negligence by the doctor and possibly illegal behaviour by an unqualified technician. The post sparked discussion about seeking legal action, as well as criticism of the clinic's high cost.

community The Worst Hair Loss Condition You (MAY) have: LPP

in Research/Science 43 upvotes 6 months ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community scarring alopecia awareness in this community

in Chat 33 upvotes 2 years ago

Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

community Making the jump to hair systems

in Hair Systems 26 upvotes 3 years ago

19-year-old with Lichen Planopilaris tried various treatments unsuccessfully. Now considering hair systems, seeking experiences and opinions.

community Losing Hair on Dutasteride? You might have LPP

in Research/Science 96 upvotes 3 weeks ago

Men with hair loss might have lichen planopilaris (LPP), which can mimic androgenetic alopecia, leading to misdiagnosis and ineffective treatment with finasteride or dutasteride. Proper diagnosis, including biopsies, is crucial to distinguish between androgenetic alopecia and conditions like LPP.

community Anger and frustration as I finally learn my diagnosis.

in Female 6 upvotes 1 year ago

A young female diagnosed with Lichen planopilaris (LPP) experienced years of misdiagnosis and ineffective treatments, including a hair transplant and other procedures. She is considering litigation due to the misdiagnosis and has learned that LPP is chronic, hair loss can be stopped with ongoing medication, but lost hair cannot regrow.

community You will lose hair if your prostaglandins aren't in balance

in Research/Science 55 upvotes 6 days ago

Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.

community What are all the blood work that can be checked for potential causes of hair loss?

in Research/Science 6 upvotes 2 weeks ago

The conversation is about potential causes of hair loss and treatments, including topical and oral minoxidil, finasteride, and dutasteride, with a focus on checking for vitamin deficiencies and conditions like Lichen Planopolaris. It also discusses the skepticism around certain tests and the success of hair transplants.

community Hair Loss & Lipids: Why you have sebderm, folliculitis, LPP, inflammation, etc...

in Research/Science 131 upvotes 1 week ago

Excess sebum rich in cholesterol and triglycerides can lead to hair loss through inflammation, with treatments like Ciclopirox shampoo, Benzoyl Peroxide shampoo, and Clindamycin gel recommended for managing conditions like seborrheic dermatitis and folliculitis. Pioglitazone is suggested for Lichen Planopilaris, while Omega-3s and reducing processed foods may improve sebum quality, though genetic factors play a significant role.

community Can gains from stemoxydine be permanently kept with 5AR inhibitors?

in Research/Science 2 months ago

Stemoxydine's effects on hair growth are uncertain and not well-studied, with users reporting mixed results and concerns about maintaining gains. Some users combine it with 5AR inhibitors like Dutasteride, but results vary, and conditions like lichen planopilaris complicate treatment.

community Clascoterone (Winlevi) Update for Canada

in Treatment 16 upvotes 2 years ago

Clascoterone cream was submitted for review to Health Canada in August 2022, with hopes of approval within 3-6 months. It may potentially enhance finasteride's effects for hair loss treatment.

community Turning vellus hairs into terminal hair

in Research/Science 12 upvotes 5 months ago

People are discussing hair loss treatments, including minoxidil, finasteride, and RU58841, to turn vellus hairs into terminal hairs. Some users also mention using antibiotics, oral minoxidil, dutasteride, DHT blockers, biotin, and natural remedies like onion juice and seeds to improve hair growth.

community Dutasteride Literally Saves Your Hair

in Finasteride/Dutasteride 100 upvotes 9 months ago

Dutasteride significantly reduces scalp DHT levels and can save hair, though shedding is part of the process. Some users report success with dutasteride, while others struggle despite using it along with finasteride and oral minoxidil.

community 6 week update fellas, 5mg oral minoxidil. Pics are 2nd June – 10th July

in Progress Pictures 2 years ago

, you can find it online with a script This user was discussing their progress with hair loss treatments including 5mg oral Minoxidil and combining 3mg oral Minoxidil with MTF HRT. They also discussed side effects of increased body hair in other parts of the body.

community I cry every day, everything is very depressing

in Finasteride/Dutasteride 52 upvotes 1 week ago

A user is experiencing hair loss despite using dutasteride and oral minoxidil, feeling hopeless and considering a hair system. They are advised to try ketoconazole, seek a second opinion from a dermatologist, and consider treatments like finasteride, RU58841, and hair transplants.

community Treatments not working (Need suggestions)

in Finasteride/Dutasteride 2 upvotes 1 week ago

A 21-year-old experiencing significant hair loss despite using dutasteride, oral minoxidil, ketoconazole shampoo, and low-level laser therapy seeks advice. Suggestions include adding microneedling, checking for vitamin deficiencies or thyroid issues, and considering a scalp biopsy for other conditions.

community DUPA/Retrograde might not be DHT based...GET A BIOPSY QUICK or permanent Hair Loss!

in Research/Science 40 upvotes 1 month ago

DUPA and retrograde alopecia may not be solely DHT-based, and a biopsy is crucial for accurate diagnosis and treatment. Treatments mentioned include dutasteride, oral minoxidil, pioglitazone, clobetasol, calcipotriol, ketoconazole, and doxycycline, depending on the specific condition.

community What is this pigmentation around my follicles?

in Chat 29 upvotes 2 months ago

The conversation discusses potential causes of pigmentation around hair follicles, suggesting sebum buildup, autoimmune conditions, or dermatitis. Treatments mentioned include finasteride, dutasteride, and an anti-inflammatory diet, with a recommendation to consult a doctor for a proper diagnosis.

community DUPA VS. FAPD, which is more treatable? Which is worse?

in Research/Science 8 upvotes 3 months ago

DUPA is considered more treatable than FAPD, as FAPD involves scarring that prevents hair regrowth. The user has started treatment with oral dutasteride and minoxidil, hoping for better results than previous treatments.

community He used Dutasteride for 20 years. Interview

in Treatment 110 upvotes 4 months ago

Dutasteride has been used for 20 years with some hair thickness improvement but no dramatic regrowth. The user also experimented with minoxidil, tretinoin, and peptides like BPC 157 for potential benefits in hair density and quality.

community How essential is scalp biopsy when dealing with hair loss?

in Treatment 6 upvotes 5 months ago

The user experienced hair loss despite using Fin and Min for 12 years and switched to Dutasteride, RU58841, and Keto scalp serum, but shedding and itch persist. They are considering increasing Dutasteride to 2.5mg and questioning the necessity of a scalp biopsy, with mixed opinions on its usefulness.

community “Progress” pictures. Should I just give up?

in Journals / Progress Pictures 239 upvotes 6 months ago

The user has been using Finasteride and Minoxidil for hair loss but has seen no progress. Suggestions include trying Dutasteride, increasing Minoxidil dosage, or considering a hair transplant.

community We Need A Solution For The Inflammatory Response related To AGA

in Research/Science 16 upvotes 7 months ago

The conversation is about finding a solution for scalp inflammation related to AGA, with the user expressing frustration that Minoxidil and Finasteride do not address inflammation. The user has researched glucocorticoids and topical NSAIDs for reducing inflammation and seeks advice from specialists.

community 2 Years Fin 1mg ED + 7 1/2 months Min topical 1x ED results

in Progress Pictures 77 upvotes 11 months ago

A 20-year-old with diffuse hair thinning has been using finasteride daily for 2 years and added topical minoxidil once daily at night for the past 7.5 months, seeing improved results. They are switching to oral minoxidil for convenience and will update on the outcome.