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Did you mean Gonadotropin-releasing hormone?

Glossary Gonadotropin-releasing hormone

regulates release of reproductive hormones from the pituitary gland

Gonadotropin-releasing hormone (GnRH) is a key hormone produced in the hypothalamus of the brain. It regulates the release of two other important hormones from the pituitary gland: luteinizing hormone (LH) and follicle-stimulating hormone (FSH). These hormones are crucial for reproductive function, including the development of eggs in ovaries and sperm in testes.

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community My Estradiol Level on Finasteride

18 upvotes 1 year ago

Finasteride has no effect on the user's estradiol levels, and body fat may influence aromatization. The user is on testosterone replacement therapy and uses everyday injections to manage high RBC count, with plans to measure DHT, DHEA-S, and pregnenolone levels.

community Experiences of regrowth on HRT

14 upvotes 1 week ago

A 23-year-old is experiencing hair loss and is using a regimen including topical Minoxidil, finasteride, spironolactone, and Estradiol gel as part of hormone replacement therapy (HRT). They are hopeful for hair regrowth and are considering using a micro needler, with others suggesting that their current treatment could lead to significant improvement.

community What happens if you combine dutasteride and a aromataze inhibitor?

4 upvotes 7 years ago

Combining dutasteride and an aromatase inhibitor may increase testosterone levels significantly, potentially enhancing athletic performance but also posing health risks like elevated blood pressure and worsened cholesterol. The user is experimenting with dutasteride, anastrozole, minoxidil, and ketoconazole shampoo to manage hair loss and estradiol levels, while monitoring side effects and hormone levels.

community What are your thoughts on pre-finasteride blood work?

1 upvotes 3 years ago

The user is considering resuming finasteride after a 6-month break and is debating the necessity of extensive blood work, including hormone and health markers, to establish a baseline. They are unsure if the tests are necessary since they experienced no side effects previously.

community What makes them say exercise doesn't increase hair loss?

in Research/Science 45 upvotes 1 year ago

Exercise has minimal impact on hair loss, with weight lifting slightly increasing DHT and cardio potentially decreasing it. Finasteride and dutasteride are effective treatments for managing hair loss, even for those who exercise regularly.

community Be careful when switching from Finasteride to Dutasteride because for more efficacy.

in Finasteride/Dutasteride 13 upvotes 1 year ago

Switching from finasteride to dutasteride may be more effective for hair regrowth due to dutasteride's stronger enzyme inhibition, but combining both drugs could enhance results. Some users report better outcomes with dutasteride, while others recommend a gradual transition to prevent potential hair loss.

community Any other non-responders to most medications?

6 upvotes 3 years ago

The user has not seen results from various hair loss treatments including finasteride, dutasteride, minoxidil, and others over several years and is considering adding RU58841 and starting hormone replacement therapy. They are also experiencing anxiety and contemplating moving to a more accepting environment for their nonbinary identity.

community HRT temple regrowth - 0 months, 3 months, 6 months

22 upvotes 2 months ago

The conversation is about hair regrowth progress using hormone replacement therapy (HRT) with Estradiol and Cyproterone, without using Minoxidil. The user shares progress pictures over 0, 3, and 6 months.

community I don’t understand this, is he equating taking Fin with being on HRT?

303 upvotes 1 year ago

The conversation is about using finasteride and testosterone replacement therapy (TRT) for hair loss and their role in gender-affirming care. It debates whether these treatments are considered hormone replacement therapy (HRT) and their implications for both cisgender and transgender individuals.

community Yet another hrt update (4 months estradiol and spiro + > 4 years of fin and min) (you should absolutely not take estradiol and spiro if you look manly and want to continue to look manly)

4 upvotes 1 year ago

The conversation discusses hair loss treatments, including finasteride, minoxidil, estradiol, and spironolactone, with a focus on their effects on hair regrowth and gender transition. The original poster shares their personal experience with these treatments, emphasizing that estradiol and spironolactone should not be used by those who want to maintain a masculine appearance.

community Guaranteed Way to Revive ALL Follicles. Transition, and then Transition Back & Maintain (for Men)

250 upvotes 1 year ago

Transitioning genders humorously suggested for hair regrowth, noting some transgender individuals experience this. Discusses treatments like minoxidil, finasteride, and hormone therapy, but advises against transitioning solely for hair regrowth.

community IGFBP‐rP1 is a potential therapeutic target in androgenic alopecia

in Research/Science 13 upvotes 1 year ago

IGFBP‐rP1 shows potential for treating androgenic alopecia by influencing hair cycle transitions. Increasing IGF-1 levels may have similar effects to Minoxidil and 5-AR inhibitors in reducing hair loss.

community Injecting estrogen for hairline regrow

268 upvotes 1 year ago

A user plans to undergo a temporary MtF transformation to regrow hair, using estrogen, RU58841, and Dutasteride, then revert with testosterone. Many users criticize the plan, suggesting alternatives like hair transplants, and emphasize that estrogen is not a reliable solution for hair regrowth.

community What hormones should I have tested at a minimum before starting a DHT blocker or anti-androgen?

4 upvotes 2 years ago

The conversation is about someone planning to start finasteride or RU58841 for hair loss and wanting to know which hormones to test beforehand. They found a package for testing testosterone, free testosterone, estradiol, and DHT, and are asking if these tests are enough.

community (MTF 35) 20 Months Feminizing HRT

in Transgender 18 upvotes 7 months ago

A 35-year-old transgender woman experienced hair regrowth with feminizing HRT, adding dutasteride and bicalutamide, and plans a hair transplant for further improvement. Estrogen also improved skin appearance, and the user advises against cisgender men using feminizing HRT for hair regrowth.

community Running Gear- Preemptive Treatment

in Product 11 months ago

A 51-year-old on TRT plans to use steroids and is concerned about hair loss, considering topical treatments like Hair Rescue with RU58841 and finasteride, along with Nioxin shampoo. They are cautious about using oral DHT blockers due to potential interactions with steroids like Tren and Anavar.

community Why Fin/Dut Isn't Working for You GPR133: a new hairloss mechanism + Steroid Hair Loss Deep Dive

6 upvotes 1 month ago

Hair loss may be linked to the GPR133 receptor, independent of the androgen receptor pathway. Treatments like finasteride, dutasteride, minoxidil, RU58841, and KX-826 show varying results, with hair loss persisting due to high testosterone and GPR133's role.

community Regrowth after 9 months of DHT blockers, and 6 months of HRT

in Transgender 24 upvotes 10 months ago

A 20-year-old saw significant hair regrowth after 9 months of using DHT blockers (finasteride and dutasteride) and 6 months of hormone replacement therapy (HRT) with estradiol. The regrowth is attributed to low testosterone and high estradiol levels, without using Minoxidil.

community (MTF 35) Results of 18 Months of HRT

775 upvotes 8 months ago

A transgender woman experienced significant hair regrowth after 18 months of hormone replacement therapy (HRT) with estrogen and bicalutamide. The discussion notes HRT's effectiveness for hair regrowth but warns against its use for cisgender men due to feminizing effects.

community Can you take something like Spiro or even Estradiol if already on low dose TRT to regrow hair?

3 upvotes 1 year ago

The conversation discusses using treatments like dutasteride, minoxidil, spironolactone, and estradiol for hair regrowth while maintaining muscle mass. Concerns include potential side effects like gynecomastia and muscle loss, with suggestions to balance hormone levels carefully.

community AH-001 another topical AR degrader beside GT20029, completed Phase I

8 upvotes 10 months ago

AH-001 is a new topical treatment designed to degrade androgen receptors, targeting the root cause of androgenetic alopecia without the side effects of oral treatments like finasteride. It has shown a strong safety profile and good local tolerability in early trials.

community Taking HRT medication not only cured my thinning hair, it gave me better hair than I ever had before

in Transgender 12 upvotes 9 months ago

Hormone replacement therapy with spironolactone and estradiol significantly improved hair thickness and growth, surpassing previous treatments like dutasteride, finasteride, and minoxidil. The user experienced regrowth in receded areas and a more youthful appearance.

community PRP + GFC for hair regrowth?..

2 upvotes 2 years ago

A dermatologist recommended PRP (Platelet Rich Plasma) and GFC (Growth Factor Concentrate) for pattern baldness, but online sources suggest they may not be effective. The user is seeking opinions on these treatments.

community Hair regrow idea: High dose Testosterone + RU58841

in Satire 2 upvotes 4 months ago

Using high doses of testosterone with RU58841 to create an androgen-free environment for hair regrowth is suggested, but concerns about heart health and the effectiveness of this approach are raised. Alternatives like topical estrogen, progesterone, and other treatments like finasteride and dutasteride are discussed.

community Possible explaination for Finasteride Reflex Hyperandrogenicity

6 upvotes 4 years ago

The user has been using finasteride and minoxidil for hair loss but experienced worsening temple recession. They suspect they might be more sensitive to testosterone and are considering trying RU58841 or CB 03 01 as additional treatments.

community 2 years on treatment (stack update)

465 upvotes 1 year ago

A user shared their hair regrowth progress using Dutasteride, topical Minoxidil, Spironolactone, and Estradiol Valerate injections as part of hormone replacement therapy for transitioning. They experienced significant hair improvement and personal satisfaction but caution against this approach for non-transitioning individuals due to irreversible changes.

community Androgen degraders for hair loss

61 upvotes 2 years ago

The conversation discusses androgen receptor degraders for hair loss, highlighting their potential advantages over traditional AR blockers like RU58841 and pyrilutamide. Concerns about the safety and cost of these treatments are also mentioned.

community Mechanism of Action these drugs re-grow hair?

2 upvotes 2 years ago

Minoxidil, finasteride, and RU58841 promote hair growth by different mechanisms, with minoxidil and prostaglandin E1 being specifically mentioned. Corticosteroids can also cause hair growth.

community Does anyone have any experience with Estradiol, Cyproterone Acetate, Spironolactone, Bicalutamide ?

4 upvotes 6 years ago

Some users have experienced good hair regrowth with estradiol, cyproterone acetate, spironolactone, and bicalutamide, but these treatments may cause feminization and other side effects. It's advised to consult a doctor before using these treatments, as they can lower testosterone and have significant risks.

community 11 months progress, HRT + Fin + Min

in Progress Pictures 366 upvotes 5 months ago

A transwoman shared her 11-month progress using hormone replacement therapy (HRT), finasteride, and minoxidil, reporting significant hair regrowth and satisfaction with the results. The discussion included various perspectives on HRT, its effects on hair and sexual function, and personal experiences with similar treatments.