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GlossaryGenetic Loci for Patterned Hair Loss Susceptibility

specific gene locations linked to increased risk of hair loss

Genetic loci for patterned hair loss susceptibility refer to specific locations on genes that are associated with an increased risk of developing patterned hair loss, such as male or female pattern baldness. These loci contain variations in DNA that can influence how likely a person is to experience hair thinning or loss, often inherited from their parents. Understanding these genetic markers helps researchers and medical professionals identify individuals at higher risk and develop targeted treatments.

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community Evidenced Based Meta-Analyses and Systemic Reviews of Androgenic Alopecia and Treatments

in Research/Science 15 upvotes 4 years ago

Evidence-based treatments for androgenic alopecia, such as minoxidil, finasteride, low-level laser light therapy, dutasteride, platelet-rich plasma, and topical ketoconazole. It discusses the efficacy, safety, and mechanism of action of these treatments, as well as future developments in understanding this polygenic condition.

community Why is nobody studying the difference between donor and balding hair?

in Chat 89 upvotes 5 months ago

The conversation discusses why the difference between donor and balding hair isn't studied more to find a cure for hair loss. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Dermatologist told me to quit fin after turning 40

in Finasteride/Dutasteride 194 upvotes 1 year ago

A dermatologist advised a patient to stop taking finasteride (fin) after turning 40 due to potential risk of aggressive prostate cancer. The patient and others in the conversation debated this advice, discussing the relationship between finasteride, prostate cancer, and hair loss, and considering alternatives like topical finasteride.

community Genetic testing to determine individualized hairloss treatment?

in Research/Science 10 upvotes 1 year ago

A user discusses a company, Roots by Genetic Arts, that offers a genetic test for hair loss to create personalized treatments, and is curious about its legitimacy and the science behind it. The company tests 16 genes related to hair loss and compounds a topical treatment based on the results.

community Is Fagron TrichoTest (first genetic test for hair loss) a SCAM?

in Research/Science 8 upvotes 1 year ago

User ronopibf discusses Fagron TrichoTest, a genetic test for hair loss, and seeks opinions on its effectiveness. Some users support the service, while others call it a scam, with prices ranging from $200-$500.

community My hair journey as a 20+ year old with genetic hair loss and thoughts of pregnancy soon

in Female 1 upvotes 1 month ago

A 28-year-old woman with genetic hair loss has tried various treatments, including oral minoxidil, finasteride, dutasteride, vitamins, ketoconazole shampoo, exosome needling, and hair extensions. She plans to pause treatments for pregnancy and is concerned about potential hair loss during that time.

community DNA Testing by Roots by Genetic Arts

in Research/Science 3 upvotes 8 months ago

A user shared their positive experience with Roots by GA, a company that creates personalized hair loss treatments based on DNA analysis, which confirmed their inability to tolerate finasteride. The user is satisfied with their progress 30 days after a hair transplant and the customized formula they received.

community Female diffuse hair loss on spiro with irregular periods (photos) + genetic hair loss

in Female 17 upvotes 1 month ago

A 34-year-old woman is experiencing diffuse hair loss and irregular periods, possibly due to long-term spironolactone use. She is considering minoxidil and finasteride for treatment and seeking medical advice for androgenic alopecia and hormonal imbalances.

community The closest thing to a cure before hair cloning or genetic via?

in Treatment 9 upvotes 1 year ago

The conversation discusses using finasteride or dutasteride to reduce DHT, CosmeRNA to target androgen receptors, and Minoxidil as a vasodilator for hair growth. The regimen aims to maintain hair by addressing DHT-AR ratio and continuous Minoxidil use.

community CRISPR Is Curing People Right Now. Genetic Hair Loss is Next?

in Technology 107 upvotes 1 month ago

CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.

community Do we know exactly why some people respond so great to dut/fin,min and others dont?

in Research/Science 29 upvotes 1 week ago

Genetic factors, enzyme activity, and DHT sensitivity affect individual responses to hair loss treatments like finasteride, minoxidil, and dutasteride. Starting treatments early can slow hair loss, but results vary among individuals.

community Vegan Protein Powder Make Loss Worse?

in Female 2 upvotes 3 months ago

A user is experiencing genetic hair loss and is using spironolactone and minoxidil without success. They are considering switching to vegan protein powder due to digestive issues and are concerned if it will worsen hair loss.

community Welcome to Tressless, OG! Ötzi was dark-skinned and balding.

in Chat 11 upvotes 1 year ago

The conversation discusses that genetic analysis of the Iceman Ötzi shows he had male-pattern baldness and dark skin, with a joke about using beards and tattoos to distract from hair loss. No specific hair loss treatments are mentioned.

community How does hair loss and recovery work?

in Chat 12 upvotes 2 months ago

Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

community 29f Female on Dutasteride Progress.

in Female 14 upvotes 1 year ago

A 29-year-old woman with genetic hair loss started using 0.5 dutasteride a week ago and has noticed increased shedding, no sexual side effects, and less oily skin. She plans to provide updates and is not concerned about potential birth defects as she doesn't plan to have more children.

community Do I need to get professional advice?

in Advice 6 upvotes 5 years ago

A 22-year-old woman is experiencing genetic hair loss and has tried natural remedies like coconut oil and aloe vera without success. She seeks advice on whether to see a dermatologist or use treatments like Minoxidil (Rogaine) despite her parents' skepticism about professional help and chemical treatments.

community Hair growth and natural remedies? Are they worth of it ..

in Treatment 1 upvotes 4 months ago

The user discusses using Minoxidil and plans to start Finasteride for genetic hair loss. They also mention natural remedies like gold shilajit, moringa powder, a seed mixture, and cardio exercise, emphasizing that while these can help, Minoxidil and Finasteride are necessary.

community Hair loss and ethnicity - Caucasian men the most likely to experience hair loss

in Chat 17 upvotes 1 year ago

The conversation discusses how Caucasian men are more likely to experience hair loss due to genetic predisposition, with factors like the androgen receptor on the X chromosome playing a significant role. The user also expresses confusion about the evolutionary reasons for hair loss, especially in colder climates where it would seem beneficial to retain hair for warmth.

community Is there any way to know for sure if hair thinning is just from fungal infection/ inflammation and would be reversed with just Ketoconazole 2%/ triamcinolone acetonide etc?

2 upvotes 9 years ago

The user is unsure if their hair thinning is due to fungal infection/inflammation or genetic factors and is hesitant to start Minoxidil, finasteride, and RU58841. They are currently using Ketoconazole 2% and triamcinolone acetonide and are concerned about potential side effects from other medications.

community abusing caffeine boosts DHT levels!

in Research/Science 1 upvotes 1 month ago

Caffeine intake may increase DHT levels, but its impact on hair loss is minimal compared to genetic factors. Excessive caffeine can cause health issues, and its effects on hair loss are not directly applicable to humans based on rat studies.

community I want to sacrifice my hair in the name of science

in Chat 12 upvotes 1 year ago

The conversation discusses various theories of hair loss, including DHT sensitivity and genetic factors, with the user willing to use themselves for research due to having a hair loss gene but different hair loss patterns compared to their brothers. Specific treatments were not mentioned in the provided text.

community Dutasteride might be better for your hairline. Some people have more type 1 5AR activity in their scalp than others.

in Finasteride/Dutasteride 52 upvotes 1 year ago

Dutasteride might be better for hairline due to varying levels of 5AR activity in scalps. Genetic tests can determine if finasteride is enough or if dutasteride is needed.

community Finasteride gives me seb derm. Thoughts on zinc or other options?

in Chat 15 upvotes 2 years ago

A user with diffuse hair loss after taking accutane, which might have triggered genetic predisposition to AGA; their experience taking finasteride and experiencing side effects of increased oil production, increased sex drive, worsening hair texture; they are considering zinc supplementation with finasteride or other treatments such as alfatradiol or spironolactone.

community Still not sure why men think diet has nothing to do with hair loss when scientific is quite the opposite [Link]

25 upvotes 6 years ago

Diet can influence hair health, but male pattern baldness (MPB) is primarily genetic. Treatments discussed include Minoxidil, finasteride, and RU58841.

community Does dutasteride stop hair loss forever?

in Finasteride/Dutasteride 38 upvotes 2 weeks ago

Dutasteride and finasteride can significantly slow or halt hair loss, with some users experiencing regrowth, but results vary. Lifestyle factors and individual genetic predispositions also play a role in hair loss outcomes.

community Dutasteride/RU/MIN will NOT work for everyone.

in Finasteride/Dutasteride 1 upvotes 3 weeks ago

Hair loss treatments like Dutasteride, RU58841, and Minoxidil may not work for everyone, as some individuals experience no improvement despite extensive use and research. Genetic factors can play a significant role, and standard treatments may not be effective for all.

community 2Y 5M on dut, ask me anything

in Finasteride/Dutasteride 130 upvotes 1 month ago

A user experienced significant hair regrowth using dutasteride without side effects, starting with finasteride and not using minoxidil or dermarolling. They attributed success to a unique genetic response to DHT blockers but did not share their full regimen, frustrating others.

community Questions about a year of hairloss

in Treatment 1 upvotes 3 months ago

A 38-year-old man experiencing rapid hair loss plans to try minoxidil and a derma roller, and may consider finasteride if there's no improvement in six months. He seeks advice on genetic hair loss, baseline baldness, dandruff shampoo, and alternative treatments like tea tree oil and rosemary oil.

community Age 21 to 25, N3 to N2 in 4 years

in Progress Pictures 3 months ago

A user shared their hair regrowth journey from age 21 to 25 using finasteride and a carnivore diet. Other users debated the effectiveness of diet changes versus genetic factors in hair loss.

community Would starting dutastride and some other activities that probably raise testosterone increase the chance of side effects?

in General 66 upvotes 4 months ago

Combining finasteride and dutasteride with activities that raise testosterone may increase the risk of side effects like gynecomastia, depending on genetic predisposition and hormone levels. It's advised to check hormone levels to assess the risk.