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GlossaryGenetic Basis

underlying genetic factors influencing a trait or condition

The term "Genetic Basis" refers to the underlying genetic factors that contribute to the development of a particular trait or condition. This includes specific genes, gene variants, and their interactions that influence the manifestation of characteristics such as hair color, susceptibility to alopecia, or other biological traits. Understanding the genetic basis helps in identifying the hereditary components and potential genetic causes of these traits or conditions.

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community 22M | 18 Weeks Progress | Very rapid and aggressive Hairloss since 17 and only learned about Min, Fin, etc. a few months ago | Words can't describe how happy I am with these results and the gains keep coming.

in Progress Pictures 86 upvotes 10 months ago

A 22-year-old man has seen significant improvement in his hair loss after 18 weeks using Minoxidil and Finasteride, starting treatment after rapid hair loss since age 17. He applies Minoxidil directly after an unspecified procedure, believing it's more effective and appreciates the sterilizing effect of the ethanol in it.

community 25 Years old. 3 Months on Fin/Min, plus Hair & Nail Vitamins.

in Progress Pictures 379 upvotes 1 year ago

The conclusion of the conversation is that the user, Lead_Tasso, is expressing gratitude for the community's help in restoring their confidence in treating hair loss. They have been using finasteride (fin) and minoxidil (min) and have also been taking hair and nail vitamins.

community I am a dermatologist with a clinical interest in alopecia. AMA

in Will treatment work for me? 2 years ago

In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

community Neck tension, and hair loss, I am 100 percent sure that there is a connection

in Treatment 19 upvotes 4 months ago

The user believes neck tension and poor posture contribute to hair loss, noticing improvements with yoga and muscle relaxation. Replies suggest androgenic alopecia as the cause and recommend exercises.

community Why a lot of people seems to hate on topical fin even though it suppresses more scalp dht?

in Chat 20 upvotes 1 week ago

Topical finasteride may reduce more scalp DHT but is seen as inconsistent and messy compared to oral finasteride. Users report mixed results with both forms, with some preferring oral for its convenience and consistent dosing, while others find topical effective but harder to apply.

community How did you get over the fear mongering of Fin/Dut?

in Finasteride/Dutasteride 62 upvotes 1 month ago

The conversation is about overcoming fear of finasteride/dutasteride for hair loss treatment. Users suggest starting with a small supply, noting side effects are rare and reversible, and emphasize personal comfort and confidence.

community Huberman tweet about finasteride

in Finasteride/Dutasteride 278 upvotes 10 months ago

The conversation is about the side effects of finasteride, including Post Finasteride Syndrome, with varied personal experiences and differing views on the credibility of information sources. Some participants also discuss using minoxidil as a hair loss treatment.

community 1 year of regular fin after years of anxiety

in Update 94 upvotes 1 year ago

User GreatCanuck experienced hair regrowth after using finasteride for a year, reducing anxiety about hair loss. Others in the conversation shared similar positive experiences and discussed family members using the treatment.

community Finasteride/dut. causes NAFLD,IR,diabetes,kidney dysfunction is it correct.

in Finasteride/Dutasteride 139 upvotes 1 year ago

Hair loss discussion mentions treatments like Finasteride, Dutasteride, and Minoxidil. Users share experiences, side effects, and advice on using these treatments.

community Boys I am just a gonner. What on earth is my scalp even going through. Looks like world war 3. Pyril 3 months. Topical melitonin/progesterone/fin, dut, fin, oral min, laser trash, anus stimulation. Nothing. Donor area is decimated 😂.

in Progress Pictures 83 upvotes 1 year ago

Treating Seborrheic Dermatitis, a fungal scalp condition which can cause hair loss. Treatments discussed include antifungal shampoos, cold showers, exfoliating the scalp, taking Vitamin D, and stimulating the prostate through the anus.

community My barber is seriously making me lose hope

in Minoxidil 1 year ago

This conversation is about a user struggling with hair loss who has been told by their barber that minoxidil does not work and the only solution is to accept it. Other users have encouraged them to continue using finasteride and minoxidil, as well as look for another barber, since these treatments are scientifically proven to be effective in combating hair loss.

community Shedding like craaazzy but my hair is stable (I think) what the fuck honestly

in Finasteride/Dutasteride 10 upvotes 3 months ago

Specialist_Soup_2289 is experiencing severe hair shedding despite using finasteride, dutasteride, and oral minoxidil. They hope for regrowth but are currently shedding a lot of hair.

community My experience and a discourse on “DUPA”

in Chat 46 upvotes 1 year ago

How diffuse unpatterned alopecia (DUPA) is not an invitation to self-diagnose oneself with aggressive AGA and that seeking a specialized dermatologist may help people experiencing hair loss. Treatment options discussed include topical clobetasol propionate, oral minoxidil, and discontinuing finasteride.

community About the CBD regrowth study : just a few remarks

in Research/Science 167 upvotes 3 years ago

CBD in an emu and lanolin oil preparation showed a 100% increase in hair growth, but the effectiveness may partly come from the oils. Users discussed proper CBD dosage, preparation methods, and skepticism about the study's quality.

community Spironolactone for 11 years, finasteride for almost 5 years, started oral minoxidil in November 😢 ended oral contraceptive in Dec.

in Progress Pictures 224 upvotes 6 months ago

A user shared their 11-year experience with spironolactone and nearly 5 years with finasteride for hair loss, recently adding oral minoxidil and stopping birth control. Various treatments were discussed, including organic options, checking for underlying health issues, considering dutasteride, and the potential role of progesterone in hair loss.

community In my opinion baldness is more prevalent now and it's being ignored..

in Chat 236 upvotes 1 year ago

The conversation is about the prevalence of baldness among young men and the potential factors contributing to it. Specific treatments mentioned include minoxidil and finasteride.

community Genetic testing to determine individualized hairloss treatment?

in Research/Science 10 upvotes 1 year ago

A user discusses a company, Roots by Genetic Arts, that offers a genetic test for hair loss to create personalized treatments, and is curious about its legitimacy and the science behind it. The company tests 16 genes related to hair loss and compounds a topical treatment based on the results.

community GT20029 - Promising phase II results

in Research/Science 15 upvotes 5 months ago

GT20029 showed significant hair growth and safety in phase II trials, with no adverse sexual events. Users are hopeful but concerned about future costs and systemic effects.

community DNA Testing by Roots by Genetic Arts

in Research/Science 3 upvotes 7 months ago

A user shared their positive experience with Roots by GA, a company that creates personalized hair loss treatments based on DNA analysis, which confirmed their inability to tolerate finasteride. The user is satisfied with their progress 30 days after a hair transplant and the customized formula they received.

community Questions about a year of hairloss

in Treatment 1 upvotes 1 month ago

A 38-year-old man experiencing rapid hair loss plans to try minoxidil and a derma roller, and may consider finasteride if there's no improvement in six months. He seeks advice on genetic hair loss, baseline baldness, dandruff shampoo, and alternative treatments like tea tree oil and rosemary oil.

community Is Fagron TrichoTest (first genetic test for hair loss) a SCAM?

in Research/Science 8 upvotes 1 year ago

User ronopibf discusses Fagron TrichoTest, a genetic test for hair loss, and seeks opinions on its effectiveness. Some users support the service, while others call it a scam, with prices ranging from $200-$500.

community Evidenced Based Meta-Analyses and Systemic Reviews of Androgenic Alopecia and Treatments

in Research/Science 15 upvotes 4 years ago

Evidence-based treatments for androgenic alopecia, such as minoxidil, finasteride, low-level laser light therapy, dutasteride, platelet-rich plasma, and topical ketoconazole. It discusses the efficacy, safety, and mechanism of action of these treatments, as well as future developments in understanding this polygenic condition.

community CRISPR Is Curing People Right Now. Genetic Hair Loss is Next?

in Technology 107 upvotes 1 week ago

CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.

community Do I need to get professional advice?

in Advice 6 upvotes 5 years ago

A 22-year-old woman is experiencing genetic hair loss and has tried natural remedies like coconut oil and aloe vera without success. She seeks advice on whether to see a dermatologist or use treatments like Minoxidil (Rogaine) despite her parents' skepticism about professional help and chemical treatments.

community Age 21 to 25, N3 to N2 in 4 years

in Progress Pictures 2 months ago

A user shared their hair regrowth journey from age 21 to 25 using finasteride and a carnivore diet. Other users debated the effectiveness of diet changes versus genetic factors in hair loss.

community New Dutasteride Long Term Study (5 years) it works.

in Finasteride/Dutasteride 108 upvotes 10 months ago

The conversation discusses a five-year study on dutasteride, a medication for male hair loss. The study found that 89.9% of patients saw improvement or prevention of hair loss progression, with varying success rates based on different balding patterns. Side effects were mostly sexual and decreased over time. Dutasteride was concluded to be a long-term, safe, and effective treatment for male hair loss.

community Why is dht bad for scalp hair but good for hair on the rest of body?

in Satire 109 upvotes 1 year ago

The conversation discusses why DHT (dihydrotestosterone) negatively affects scalp hair but promotes growth elsewhere on the body. Various opinions include genetic predispositions, differences in hair follicle reactions to DHT, and the potential role of Omega-3 in reducing inflammation and promoting hair health.

community Why is there so many people claiming Dutasteride destroyed their hair?

in Chat 25 upvotes 4 months ago

Some people claim Dutasteride worsened their hair loss, causing concern among users. Reasons suggested include initial shedding phases, incorrect attribution to Dutasteride when other factors are involved, genetic variations affecting drug response, and the possibility of non-authentic medication.

community Dutasteride Vs. Testosterone, who wins?

in Finasteride/Dutasteride 58 upvotes 5 months ago

The conversation discusses whether 2.5mg of dutasteride or 200mg of testosterone weekly is more influential in preventing hair loss, with various personal experiences indicating that the effectiveness is dependent on the individual's genetic profile. Some users report that dutasteride is likely to be more effective at the given doses.

community Switched from finasteride to dutasteride - 2 month update

in Finasteride/Dutasteride 6 upvotes 10 months ago

The user switched from finasteride to dutasteride for hair loss treatment, but experienced increased libido, itchy scalp, and accelerated hair loss. Another user suggested that genetic variations might cause dutasteride to be less effective and recommended checking for specific genetic markers.