community Kintor’s KX-826 Pyrilutamide!!
KX-826 hair loss treatment completed trials with mild side effects. GT20029 may be ultimate cure, destroying androgen receptors causing baldness.
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20 / 20 resultscommunity What is the real impact of dutasteride on neurosteroids? A little review of 2 scientific datas
Dutasteride at 0.5 mg/day does not significantly alter allopregnanolone levels, but higher doses (2.5 mg/day) do. Dutasteride may also have anti-neuroinflammatory effects, but the impact on neurosteroids is still debated.
community Would there be ANY reason to still take 5AR inhibitors if pyrilutamide does what is intended?
A potential new treatment for hair loss, Pyrilutamide, and the discussion of whether or not people should still be taking traditional treatments like Minoxidil and Finasteride with it.
community DHT and 5AR respect post, it's importance within the brain
The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.
community Why is Kevin Mann (Haircafe) Hated?
Hair loss treatments, including microneedling, minoxidil, finasteride and RU58841; the efficacy of these treatments; criticisms of Kevin Mann's content related to his selective data presentation and biases towards certain treatments; and other topics such as DHT being labeled a "trash hormone" and critiques of other hairloss YouTubers.
community Completely defeated after trying so hard with topical finasteride.
A user who has tried multiple treatments for hair loss, including oral and topical finasteride and liposomal finasteride, but experienced severe side effects in each case; the user is considering trying RU58841 or aromatise inhibitors as alternatives.
community Finasteride vs Dutasteride: The Science
The conversation compares Finasteride and Dutasteride for hair loss treatment, discussing their effectiveness and side effects. Users share personal results and consider combining treatments like Dutasteride with RU58841.
community PSA: Most men who stay on Fin will see the sexual side effects go away. Stop the fear mongering
Finasteride can cause sexual side effects in less than 2% of men, but these often disappear over time, even if the treatment continues. Some users report persistent side effects, while others experience no issues or only temporary ones.
community Proof that finasteride messes with neurosteroids
Finasteride can impact neurosteroids, potentially causing depression and other side effects in some users. Despite these concerns, many continue using it for hair loss, with some switching to topical applications to mitigate side effects.
community What else can I do to compliment Minoxidil?
A user has been using minoxidil for hair loss and has seen positive results, but is seeking additional treatments to enhance its effects. One suggestion given is to use finasteride alongside minoxidil.
community Pyrilutamide vs enzalutamide. Same thing?( Especially for biochemists, farmacologists)
Researching whether pyri and enza, which are stereoisomers of each other, share the same features related to CNS penetration/GABA Inhibition; safety and efficacy when used topically at 0.5-1%; and cost comparison between the two treatments.
community Anyone else feel like a victim of medical misinformation towards finasteride?
Users discuss their experiences with finasteride, expressing regret over delayed use due to misinformation and sharing mixed outcomes, including side effects and benefits. Treatments mentioned include finasteride, dutasteride, and minoxidil.
community (M26) Can minoxidil alone maintain my hair for at least 3-4 years from now?
User with hair loss asks if minoxidil alone can maintain hair for 3-4 years. Replies suggest trying low dose topical finasteride and addressing insomnia with lifestyle changes.
community As in this research, i have seen many who advise a regular use of VitaminD, even if you are not deficient. Once i had read in tressless that mpb and Vitamin D might have a correlation. So could it be an a benefit to add this to your ongoing treatment plan?
People discussed using vitamin D supplements for hair loss, with some also using steroid injections, pumpkin seed oil, saw palmetto, and zinc. Despite supplementation, one user noted no improvement in hair condition, but acknowledged the general health benefits of addressing vitamin D deficiency.
community Over 13 months on 5% minoxidil and 6 months on finastride
A user stopped using 5% minoxidil and finasteride despite positive results to focus on enjoying life without the stress of hair care. They prioritize personal happiness and acceptance over hair maintenance.
community 6 months on biotin + minoxidil
A user shared a 6-month progress picture showing improvement in hair loss using biotin and minoxidil. They also mentioned dealing with stress, diet issues, and seborrheic dermatitis.
community I don’t even care about my hair I just like taking drugs
A user's experimentation with various hair loss treatments, including medications and topical applications; as well as their desire to experience unusual sensations through the use of drugs.
community M23 , on finaestride and minoxidil for 4.8 months
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This conversation is about a user's progress while using minoxidil and finasteride to treat hair loss, with emphasis on taking oral finasteride at night before bed for optimal results. They also discuss the brand of medication being used (Morr F 5%) and the importance of taking a generic version of the same drug.
community Progressive insomnia (treatment-resistant) due to Finasteride
A medical student experienced hair loss slowing with Finasteride but developed severe, treatment-resistant insomnia. They tried various medications with little effect, suspecting Post-Finasteride Syndrome, and others suggested the insomnia might be linked to Finasteride's impact on neurosteroids.
community I’m 14 years old and I’m losing more hair than my dad. I’ve gone to the doctor 2 times because of this and I’ve received no help. I’m starting to feel like It’s worthless and my hairs gonna look like this forever. I don’t know how anyone could help me but it’s always worth a shot.
A 14 year old who is experiencing hair loss and has not received any help from the doctor, with advice being given to try different doctors, get tested for underlying conditions and intolerances, buzz it short as an option and treatments that could slow down or reverse the hair loss such as minoxidil, finasteride, RU58841 and addressing the cause of the hair loss.