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GlossaryWnt expression

activity of genes crucial for cell signaling and hair growth

Wnt expression refers to the activity of a group of genes known as Wnt genes, which produce proteins that play a crucial role in cell signaling pathways. These pathways are essential for regulating cell growth, development, and differentiation, including the growth of hair follicles. In the context of hair biology, proper Wnt expression is necessary for the normal cycling and regeneration of hair.

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Tracking 27 products like 107 MINOXIDIL SHAMPOO FR-S1, 108 FR-C1 Conditioner, 109 FOLLICS FR07, 110 FOLLICS FR10 and 111 FOLLICS FR12 from by companies like Minoxidil Express. View all 27 products »

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community Fluridil downregulates androgen receptor expression?

in Research/Science 1 upvotes 8 months ago

Fluridil may decrease the number of androgen receptors in hair follicles by up to 95%. This suggests a different action mechanism from other non-steroidal antiandrogens like RU58841, indicating they might be used together.

community Hair Loss Breakthrough: Keratin Microsphere Gel Initiates Hair Regrowth in Days by Directly Targeting Follicles and Boosting Gene Expression - Gilmore Health News

in Treatment 468 upvotes 6 months ago

A new hair loss treatment involving Keratin Microsphere Gel is discussed, with skepticism and jokes about its effectiveness and comparisons to other treatments. Users are doubtful and make light of the situation, referencing past disappointments and the study's focus on mice.

community Start taking care of your skin and hair loss TODAY! I was telling myself I didn’t care, but I think the difference in my facial expression says it all. Take action asap before more permanent damage is done. I hope I can inspire some of you, because it’s so worth it. Not for others, for yourself! <3

in Progress Pictures 583 upvotes 2 years ago

User shared progress in treating hair loss and improving skin, using treatments like finasteride, minoxidil, RU58841, tretinoin, microneedling, and skin care regimen. Others commented on the impressive results and asked about costs and side effects.

community I gotta get this off my chest, i gotta split something

in Satire 10 upvotes 1 year ago

The conversation is a satirical expression of frustration over hair loss, mentioning treatments like spironolactone, microneedling, and topical applications, with references to various hair loss products and personalities in the community.

community Has anyone used Magnesium L-Threonate ?

74 upvotes 5 years ago

Magnesium L-Threonate may help treat balding by reducing DKK-1 expression without affecting DHT. Users discuss its potential effectiveness and application methods, with some considering trying it topically.

community here is why isotretinoin might cause hair loss and maybe why dupa happens.

in Research/Science 7 upvotes 1 year ago

Isotretinoin may cause hair loss by increasing DHT through a precursor androgen, DHEAS. Treatments like topical antiandrogens (RU58841, pyrilutamide) and drugs increasing PPAR-y expression (pioglitazone) might prevent this hair loss.

community Finasteride only reduces scalp DHT by ~40%. Why does it work?

in Finasteride/Dutasteride 37 upvotes 1 year ago

How Finasteride and Dutasteride help reduce hair loss by reducing the amount of DHT in scalp areas, as well as discussing factors such as sensitivity to DHT, 5α-reductase expression in different parts of the hair follicle, and scalp tension.

community I believe CRISPR-on & CRISPR-off is an ultimate CURE for baldness, unlike Hair Cloning or hair loss treatments.

in Research/Science 22 upvotes 3 years ago

The conversation discusses CRISPR-on & CRISPR-off as a potential cure for baldness, contrasting it with hair cloning and other treatments like Minoxidil, finasteride, and RU58841. It also mentions the potential of mRNA for gene expression control and the prioritization of gene editing for severe genetic conditions.

community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

in Research/Science 92 upvotes 2 years ago

The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

community Scientific evidence for Peppermint & Rosemary oils + My Experience

in Research/Science 114 upvotes 1 year ago

Natural treatments for hair loss, specifically peppermint oil and rosemary oil; how they can be used as a supplementary or alternative treatment to pharmaceuticals such as finasteride and minoxidil; and the personal experience of the user Divallo, who has seen an increase in density and thickness after using these oils for around 2.5 years. The post also touches on the potential antifungal properties of the oils and their effects on cutaneous blood flow.

community Saying creatine causes loss on fin/dut makes no sense and this is why

in Finasteride/Dutasteride 42 upvotes 8 months ago

The conversation discusses whether creatine causes hair loss for those using finasteride or dutasteride, with some suggesting creatine might increase DHT or upregulate androgen receptors, potentially leading to hair loss. Others argue the evidence is not conclusive, citing limited studies and personal anecdotes, with some avoiding creatine as a precaution.

community I might have found hair transplant bug guys

in Transplants 6 upvotes 7 years ago

Using finasteride before a hair transplant can prevent further hair loss and make the transplant look more natural. Patients should continue using finasteride until hair cloning becomes available.

community 5 Months Hair Transplant Progress / 3500 Grafts

in Transplants 1666 upvotes 10 months ago

A user shared their positive experience with a hair transplant of 3500 grafts, showing significant improvement in appearance after 5 months. They underwent the procedure at Heva Clinic in Istanbul for $2,300 USD, which included aftercare, and attributed their hair loss to both genetics and traction alopecia from tight hairstyles.

community When you up the dose on oral Minoxidil

in Satire 2 years ago

This conversation is a satirical post about using increased doses of oral Minoxidil as a treatment for hair loss, which elicited some humorous responses. Additionally, Finasteride was mentioned in one response as an alternative treatment option.

community Finally decided to buzz my head after experiencing hair loss since I was 17 (23 now). I think it looks decent, swipe to see what I was rocking before during the pandemic. Who knows maybe I’ll hop on fin but as someone who struggles with chronic fatigue and low test I’m hesitant.

in Shaved/buzzed 326 upvotes 2 years ago

A user's decision to shave their head after experiencing hair loss since the age of 17, and discussion around the potential use of Fin for treating hair loss.

community 10 month update! Fin/min/dermaroller/niz

442 upvotes 4 years ago

A 10 month update on the effectiveness of a hair loss treatment regimen involving minoxidil, finasteride, dermarolling and nizoral. Questions were asked about using minoxidil alone, dermaroller length, age, and when results were seen.

community Progress from one year of finasteride only.

in Progress Pictures 562 upvotes 5 months ago

A 23-year-old man shared his one-year progress using finasteride for hair loss, starting with a lower dose due to side effects and gradually increasing to 1mg. He experienced manageable side effects and is considering adding minoxidil or switching to dutasteride in the future.

community Increasing activity of the sult1a1 enzyme via alkalizing agent and tretinoin for better response to topical minoxidil

in Research/Science 4 upvotes 1 month ago

Increasing the sult1a1 enzyme on the scalp may improve response to topical minoxidil. The user suggests using a baking soda solution, DMSO, and tretinoin to enhance enzyme activity and minoxidil effectiveness.

community 8 month difference in hair (11 months on medications

in Progress Pictures 186 upvotes 2 months ago

A user shared progress pictures showing hair improvement after 11 months of using finasteride, minoxidil, and occasional microneedling. The user aims to motivate others starting similar treatments.

community Mechanism of action of alfatradiol (17 alpha estradiol)

in Research/Science 6 upvotes 4 months ago

The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.

community I used 1mm derma stamp, and rosemary oil, pumpkin seed oil for 2 months, saw baby hair growing, before there wasn't any, is this real growth or just miniaturized hair?

in Is this regrowth? 1 upvotes 5 months ago

A user reported using a 1mm derma stamp, rosemary oil, and pumpkin seed oil for 2 months and noticed baby hair growth where there was none before. They are questioning if this is real growth or just miniaturized hair.

community Medication works - First Pic June 2020

in Progress Pictures 691 upvotes 7 months ago

The user improved their hair loss using finasteride, switched to dutasteride, micro-needling, Nizoral shampoo, and changed from topical to oral minoxidil, resulting in thicker hair, eyebrows, beard, and body hair. Commenters are impressed with the transformation, some mistaking the before and after photos for different people, and the user reports no side effects from the treatments.

community Possible topical option for preventing BDNF-related hair loss

in Research/Science 7 upvotes 11 months ago

The conversation discusses hair loss linked to BDNF-increasing nootropics like Semax and Lions Mane. Suggested topical treatments include capsaicin, beta-glucan, and ginseng to counteract TGF-B activation.

community (33 M) 3 month Topical fin + Min, ru, keto, derma stamp progress

in Progress Pictures 29 upvotes 11 months ago

A 33-year-old male has been using topical finasteride, Minoxidil, RU58841, keto, and derma stamp for hair loss treatment for 3 months. He is optimistic about the promising results.

community Surprisingly thorough study on He-Shou-Wu/Fo Ti

in Research/Science 14 upvotes 1 year ago

He Shou Wu (Fo Ti) extract was found to prolong the hair growth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.

community Topical quercetin combined with finasteride for max results

in Research/Science 25 upvotes 1 year ago

Combining Finasteride with topical Quercetin, Onion/Garlic juice and Peppermint Oil to reduce Wet Prostate Weight in Rats. Luke10191 asked the user LITUATUI to update them on progress after trying this combination of treatments for hair loss.

community Is Topical Dutasteride best for preventative loss?

in Finasteride/Dutasteride 7 upvotes 1 year ago

The user is considering using topical dutasteride to prevent hair loss progression from Norwood 1 to Norwood 2 at age 25, and is concerned about the long-term effectiveness and potential shedding from the treatment. They are currently using a shampoo with caffeine, rosemary, and saw palmetto, and have noticed hair thinning and changes since age 20.

community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

in Research/Science 736 upvotes 1 year ago

A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

community Aromatase Upregulation along with DHT down regulation could possibly hold the cure

in Microneedling 7 upvotes 2 years ago

The post discusses the potential of upregulating aromatase to treat hair loss, suggesting that increasing CCL2 levels through Vitamin D or microneedling might help. The user questions why microneedling doesn't work for everyone, especially those with advanced hair loss.

community CB-03-01 supposed hair loss cure

in Treatment 6 upvotes 3 years ago

The conversation discusses why CB-03-01, a potential hair loss treatment, isn't widely discussed despite evidence of its effectiveness and safety. Some users mention other treatments like melatonin, procianidin b2, and RU58841, debating their effectiveness and safety.