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GlossaryEGFR inhibitors (Epidermal Growth Factor Receptor inhibitors)

block cell growth signals to treat certain cancers

EGFR inhibitors, also known as Epidermal Growth Factor Receptor inhibitors, are a class of drugs that block the activity of the EGFR, a protein on the surface of cells that helps them grow and divide. By inhibiting this receptor, these drugs can slow down or stop the growth of certain types of cancer cells that rely on EGFR for proliferation. They are commonly used in the treatment of cancers such as non-small cell lung cancer and colorectal cancer.

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community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth

in Research/Science 198 upvotes 2 days ago

PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.

community The Real Cause Of Androgenetic Alopecia

in Research/Science 667 upvotes 2 months ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community How all hormones affect our hair follicles. Not just DHT. Take a look at this paper. Prolactin, melatonin, cortisol, progesterone, testosterone and more

in Research/Science 126 upvotes 2 years ago

The conversation discusses various factors affecting hair loss, not just DHT, and mentions treatments like Minoxidil, finasteride, and melatonin. Some users report personal experiences with these treatments and hormone tests, while others speculate on the role of hormones like prolactin and cortisol in hair loss.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community A meta analysis of 18 popular hair loss treatments. An 2022 guide on efficacy. From finasteride and minoxidil to caffeine shampoo, saw palmetto and biotin. 96 Scientific References included.

in Research/Science 101 upvotes 2 years ago

Most hair loss treatments are ineffective; only finasteride, dutasteride, and minoxidil show effectiveness.

community Dutasteride SAVES your hair follicles: MAJOR BS on people who say it destroyed their hair permanently.

in Finasteride/Dutasteride 160 upvotes 1 year ago

The conversation discusses the effectiveness of hair loss treatments, specifically finasteride and dutasteride. The conclusion is that dutasteride significantly reduces DHT levels and may be more effective than finasteride for long-term hair retention, with some users reporting personal experiences and side effects.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 2 months ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community DIY treatment... Shedding completely stopped after 1.5 yrs

in Treatment 249 upvotes 2 years ago

Vitamin C mixed with shampoo stopped shedding and promoted hair regrowth after 1.5 years. Both the person and their wife experienced significant hair loss reduction with this method.

community Alright boys, who’s willing to burn their scalp for science?

in Research/Science 765 upvotes 1 year ago

Researching the effects of scalp trauma on hair growth, with some users suggesting experimenting with a soldering iron or derma pen, and others bringing up studies that suggest this may be an effective treatment.

community My microneedling journey (no min, fin, etc)

in Microneedling 208 upvotes 2 months ago

The user experienced positive hair growth results using microneedling with rosemary and mint oil, without Minoxidil, Finasteride, or RU58841. They switched from a dermaroller to a microneedling pen and targeted different scalp areas weekly.

community Clearing the air on how non-surgical treatments really work

18 upvotes 5 years ago

Treatments for hair loss, including finasteride, dutasteride, minoxidil, ketoconazole, microneedling, and low level laser light therapy, which aim to reduce DHT production, increase cell absorption and blood flow, and stimulate epidermal stem cells. It also stresses the importance of patience when using these treatments.

community Scalp slapping to increase blood flow?

in Treatment 22 upvotes 6 months ago

This post and conversation are about using scalp slapping to increase blood flow for hair growth. One user suggests using minoxidil instead.

community A Scientific Perspective in Microneedling for Alopecia

in Microneedling 43 upvotes 5 years ago

The post and conversation are about microneedling as a treatment for alopecia. It provides a comprehensive review of scientific literature on the technique and its application.

community Fin/min/microneedling ~9 months – no results, actually worse

in Progress Pictures 96 upvotes 1 year ago

User harlital shared their 9-month hair loss journey using finasteride, minoxidil, and microneedling but experienced worse results. Commenters suggested patience, checking for other causes, and considering dutasteride after 12-24 months if no improvement.

community Comprehensive Microneedling Guide

in Microneedling 290 upvotes 2 years ago

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

community 6 months progress no fin 27m topical foam minox

in Progress Pictures 250 upvotes 1 year ago

The user has been using 5% Minoxidil foam twice daily, microneedling every two weeks, and Nizoral 2% shampoo weekly for hair loss treatment. They've seen improvements in their hairline and eyelashes, and are considering adding finasteride to their regimen.

community New Treatments, and a Huge Group Buy with Lots of Research

in Research/Science 109 upvotes 1 year ago

A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

community Why is no one pointing out dandruff as the number 1 evidence/symptom of MPB?

in Chat 55 upvotes 1 year ago

The post discusses the theory that persistent dandruff in areas prone to hair loss could be a sign of hair follicles dying due to DHT, indicating balding. The responses vary, with some users noting improvements in dandruff and hair loss with treatments like Dutasteride, while others experienced hair loss without dandruff.

community I started rapidly diffuse thinning at 22. I'm 42 now and have as much hair as I did at 16. AMA

in Treatment 443 upvotes 4 years ago

Hair loss treatments like finasteride, minoxidil, ketoconazole, PRP, and microneedling helped maintain hair for 20 years. Research and try evidence-based treatments for best results.

community Sharing my 3.5 year journey, keep grinding guys

in Progress Pictures 228 upvotes 8 months ago

The user shared a 3.5-year hair loss treatment journey using 1 mg finasteride daily and minoxidil foam, noting significant improvement, especially in the third year. They also mentioned using Nizoral shampoo twice a week and supplements like vitamin D3, biotin, and omega 3 and 6.

community Oral minoxidil is not good for your health, let’s use research chemicals bought from AliExpress

in Satire 551 upvotes 1 year ago

. This conversation discussed the efficacy of Minoxidil and Finasteride as treatments for hair loss, with a focus on the potential side effects of taking Oral Minoxidil. Some users shared their experiences with both treatments and there was debate over whether they were safe or not.

community Vitamin C and hair growth PH levels

in Product 31 upvotes 2 years ago

The conversation is about using vitamin C and Magnesium L-Threonate for hair growth by reducing DHT binding to dermal papilla cells. The original post about vitamin C's pH levels and sebum control was possibly removed by a moderator.

community GT20029 Anageninc Market Availability

in Research/Science 164 upvotes 1 year ago

The conversation discusses the potential market release of a hair loss treatment called GT20029 by Anageninc, with users expressing interest and discussing the importance of safety and effectiveness. Some users plan to contact Anageninc to show demand for the product.

community Topical Dutasteride. Does it work?

in Finasteride/Dutasteride 13 upvotes 6 months ago

Topical dutasteride may be effective for hair loss by staying in the scalp and minimizing bloodstream absorption, potentially improving hair results and reducing side effects. The user seeks advice on its effectiveness.

community Anyone using CB-03-01? What are you thoughts? How do you get it from powder to solution? What strength should be used?

in Treatment 6 upvotes 4 years ago

The conversation is about someone considering using CB-03-01 for hair loss but has ordered finasteride, which they are hesitant to use. They are seeking advice on how to prepare CB-03-01 from powder form and the appropriate strength to use.

community Topical Finasteride Doesn't Directly Reduce 5ar Enzyme on Scalp

in Finasteride/Dutasteride 72 upvotes 1 year ago

Topical Finasteride doesn't directly reduce 5ar enzyme on scalp and has the same mechanism as oral, needing to go through the liver. Users debate the accuracy of this information and discuss various studies and experiences.

community Keratin microspheres - breakthrough

in Research/Science 13 upvotes 9 months ago

A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

community Kintor has released an investor relations memo regarding Chinese Phase III trials for Pyrilutamide

in Update 50 upvotes 1 year ago

Kintor's Pyrilutamide (KX-826) showed hair growth in Chinese Phase III trials but did not significantly outperform placebo. The treatment was safe with no major adverse reactions reported.

community New study shows .5mm microneedle to be most effective?

in Microneedling 35 upvotes 4 months ago

A user shared a video suggesting that 0.5mm microneedles are most effective for hair growth. Other users mentioned different microneedle lengths and advised consulting a dermatologist for personalized treatment.