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GlossaryDouble-Blind

neither participants nor researchers know who gets the treatment

A double-blind study is a type of scientific experiment where neither the participants nor the researchers know who is receiving the treatment and who is receiving a placebo. This method helps to eliminate bias and ensures that the results are solely due to the treatment itself, making the findings more reliable.

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community Effect of Pumpkin Seed Oil on Hair Growth in Men with Androgenetic Alopecia: A Randomized, Double-Blind, Placebo-Controlled Trial

23 upvotes 7 years ago

Pumpkin seed oil may help hair growth in men with androgenetic alopecia. Treatments discussed include Minoxidil, finasteride, and RU58841.

community Why haven’t we seen anything about this

in Research/Science 18 upvotes 4 years ago

A double blind, placebo-controlled study that looked into the potential effectiveness of topical fluridil for treating male androgenetic alopecia, showing increased anagen to telogen ratios with no reported side effects on libido or sexual performance.

community 35% regrowth brothers and sisters! More effective than Minox and Fin?

in Treatment 107 upvotes 6 years ago

A double-blind clinical study that found ingestion of tocotrienols resulted in a 34.5% increase in hair regrowth compared to the placebo group, and discussion about potential side effects and cost of supplementation with vitamin E pills. The conversation noted that it may be more effective than commonly used treatments like minoxidil and finasteride.

community Helicobacter's concocted serum v1

7 upvotes 5 years ago

A custom-made serum based on double-blind studies for AGA, which includes natural ingredients such as rosemary oil, procyanidin B-2, saw palmetto extract, curcuma aeruginosa, pumpkin seed oil and castor oil. The user has updated their recipe to include apple poly procyanidin B-2 4% concentration and other ingredients before topping it off with Pura d'or serum.

community Considering giving a laser comb a shot. Here’s a summary of my research on the subject.

8 upvotes 8 years ago

Considering adding Low Level Laser Therapy (LLLT) to a hair loss prevention regimen; discussing the effectiveness of LLLT, and evaluating double-blind random-controlled trials that have been conducted on laser combs.

community An Interesting Study With a Decent Sample Size Finding Caffeine Liquid to Have Similar Effectiveness to Minoxidil

in Minoxidil 7 upvotes 5 years ago

Caffeine liquid may be as effective as Minoxidil for hair loss and could be used together for added benefits. However, the credibility of the research is questionable due to potential bias, as the study was sponsored by a company that sells caffeine solution and was not double-blind.

community Saw Palmetto/Pumkin seed gives basically same results as Fin

in Treatment 4 months ago

A user reported that Procerin, containing Saw Palmetto and Pumpkin seed oil, provided similar hair thickening results as finasteride but with milder side effects. They experienced reduced libido and watery ejaculations but are adjusting the dose to minimize these effects.

community Pyrilutamide Results, Safety and WHERE You can BUY IT!

in Research/Science 9 upvotes 2 years ago

The conversation discusses skepticism over the results of Pyrilutamide for hair regrowth, suggesting that results from rigorous trials are more trustworthy. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.

community Amplifica’s AMP-303 Study Unveils New Hope for Hair Loss Treatments

in Treatment 39 upvotes 2 months ago

AMP-303, a new injectable treatment for androgenetic alopecia, showed promising results in increasing hair count and density with minimal side effects. The treatment demonstrated significant hair regrowth and durability, offering new hope for those with hair loss.

community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI

in Finasteride/Dutasteride 26 upvotes 4 months ago

The conversation discusses the effectiveness and skepticism around topical dutasteride for hair loss, with mentions of combining it with other treatments like minoxidil and oral medications. Some users doubt its efficacy due to lack of independent studies and potential conflicts of interest.

community Cosmo Pharma Lists Breezula Phase 3 Trial on ClinicalTrials.gov

in Research/Science 24 upvotes 1 year ago

A phase 3 trial for Breezula (clascoterone solution) to treat male pattern hair loss has been listed, with 726 participants and a completion date of January 2025. Other treatments mentioned include Aneira Pharma's combination of minoxidil and latanoprost, Triple Hair's combination of minoxidil, latanoprost, and finasteride, and a new microneedling and LLLT device called StimuSIL.

community "Minoxidil and Caffeine: Reason behind hyper responders and non-responders."

in Research/Science 31 upvotes 1 year ago

Minoxidil and caffeine may interact, affecting hair growth results. Users shared mixed experiences, with some noticing improvements without caffeine and others still seeing results despite coffee consumption.

community latanoprost, minoxidil and biotin 3/20/23 vs 5/21/23 same spot

in Progress Pictures 87 upvotes 1 year ago

Hair loss treatment with latanoprost, minoxidil, and biotin showed progress. Latanoprost, a glaucoma drug, stimulates anagen phase and increases conversion of vellus hair to terminal hair.

community Kintor Has Completed Enrollment in Phase II Clinical Trial of KX-826 (Pyrilutamide) for Treatment of Male AGA Patients in the US

in Update 23 upvotes 2 years ago

KX-826 (Pyrilutamide) being tested in the US for hair loss treatment and that they have found enough people to participate in phase II clinical trials. Other treatments discussed are Minoxidil, finasteride, and RU58841.

community Experiences with Annurmets Hair?

in Product 6 upvotes 3 years ago

User asks about Annurmets Hair product, high in Procyanidin B2 for hair regrowth. Product is expensive and ordered from Italy.

community The Effect of Intradermal Botox on Androgenetic Alopecia and Its Possible Mechanism (Journal of the American Academy of Dermatology (2020)

in Treatment 12 upvotes 4 years ago

Intradermal botulinum toxin (BTX) injections effectively treat androgenetic alopecia (AGA) by inhibiting TGF-β1 secretion from hair follicles. Further research and long-term follow-up are needed to confirm these findings.

community Most Recent Interesting Hairloss Studies: 10% Minox vs 5% Minox / Radio Rrequency Treatment for AA / Topical Ketoconazole / PRP+Minox vs Minox vs PRP / Alopecia as a systemic disease

in Treatment 88 upvotes 4 years ago

Treatments for hair loss, such as topical minoxidil, platelet-rich plasma therapy with or without minoxidil, ketoconazole, non-abative radio frequency, natural products, finasteride and cortexolone 17 alpha propionate. The post evaluates the efficacy and safety of these treatments in various studies.

community First patient dosed with Pyrilutamide (Kintor) Phase III

in Research/Science 200 upvotes 2 years ago

First patient dosed with Pyrilutamide (Kintor) Phase III for hair loss treatment. Pyrilutamide differs from approved treatments as it competes with DHT to bind hair follicles, potentially reducing side effects.

community COMPLETE OVERVIEW of the Treatment of androgenetic alopecia in men

26 upvotes 10 years ago

Male androgenetic alopecia is commonly treated with topical minoxidil and oral finasteride, both requiring continuous use. Other options include hair restoration surgery, dutasteride, light therapy, and camouflaging agents.

community New study shows minoxidil tropical solution 5% can cause eyesight problems.

in Research/Science 183 upvotes 1 month ago

Minoxidil 5% topical solution may cause eyesight problems, with some users experiencing blurred vision. The discussion also mentions finasteride's potential side effects, including erectile dysfunction, with varied personal experiences.

community Bryan (the guy who reversed aging) shares treatment that reversed his hair loss

in Treatment 1079 upvotes 1 month ago

A person improved hair loss from Norwood 3 to Norwood 2 using a topical formula with minoxidil, dutasteride, and tretinoin, plus oral minoxidil and red light therapy. There is skepticism about the treatment's effectiveness and concerns about misleading comparison photos.

community how it feels to talk to tiktok kids about hairloss that isn’t shitty rosemary oil bloodflow and microneedling

in Satire 993 upvotes 2 months ago

Minoxidil and finasteride are effective for hair loss, especially when used together. Microneedling may enhance minoxidil's effects, but its standalone effectiveness is uncertain.

community What is worth dissolving in topical minoxidil solution?

in Treatment 3 upvotes 3 months ago

Switching from minoxidil foam to topical solution and considering adding caffeine, melatonin, or cetirizine. Currently using 2.5mg oral minoxidil and 1mg oral finasteride, planning to ask for 0.5mg oral dutasteride and 5mg oral minoxidil.

community Sugars ARE important for hair growth | Glycosaminoglycans as Hair Growth Stimulant

in Research/Science 75 upvotes 4 months ago

Glycosaminoglycans are important for hair growth, and combining minoxidil with tretinoin and Biopeptide-CL may enhance hair growth by boosting glycosaminoglycan levels and improving the hair follicle environment. Users discussed the potential effectiveness and future of these treatments.

community Received Kintor’s KX-826 Today

in Product 84 upvotes 4 months ago

A user received Kintor’s KX-826/Pyrilutamide and shared initial impressions, noting concerns about the product's labeling and marketing. Other users discussed the legitimacy of the product, its effectiveness, and compared it to other treatments like Minoxidil and Finasteride.

community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

in Research/Science 134 upvotes 8 months ago

The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

community Guys hear me out we might have a breakthrough

in Satire 657 upvotes 10 months ago

The conversation is a satirical discussion about unconventional hair loss treatments, including using mold, butter, and other non-traditional substances, with no real evidence of effectiveness. Some users joke about side effects like erectile dysfunction and weight gain.

community Kintor has released an investor relations memo regarding Chinese Phase III trials for Pyrilutamide

in Update 50 upvotes 1 year ago

Kintor's Pyrilutamide (KX-826) showed hair growth in Chinese Phase III trials but did not significantly outperform placebo. The treatment was safe with no major adverse reactions reported.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

in Research/Science 65 upvotes 1 year ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community Phase II for Technoderma Therepeutic's TDM-105795 set to begin in April tentatively

in Research/Science 41 upvotes 1 year ago

Phase II for TDM-105795 for Androgenic Alopecia is set to begin in April 2023. The study aims to evaluate the efficacy and safety of TDM-105795 in male subjects.