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GlossaryDermal Augmentation

cosmetic procedure enhancing skin's volume and structure

Dermal augmentation refers to a cosmetic or medical procedure aimed at enhancing the skin's volume and structure. This is typically achieved through the injection of substances like hyaluronic acid, collagen, or fat into the dermal layer of the skin. These treatments can help reduce wrinkles, scars, and other skin imperfections, providing a more youthful and smooth appearance.

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community Currently crushing 3 (5mg) tablets of fin into my topical min. Anyone do the same? If so how much do you add.

in Treatment 186 upvotes 4 months ago

The conversation discusses using crushed finasteride tablets mixed with topical minoxidil for hair loss treatment. Users share their experiences and opinions on the effectiveness and proper concentration of this method.

community Shiseido Dermal Sheath Cup (DSC) Hair Multiplication Is Finally in Japan (on July 1)

in Treatment 25 upvotes 3 months ago

Shiseido's Dermal Sheath Cup (DSC) Hair Multiplication treatment is now available in Japan. Users discuss the treatment's availability and cost.

community Hair cloning and injection of dermal papilla cells coming as soon as 2023

in Technology 120 upvotes 2 years ago

Hair cloning and injection of dermal papilla cells are discussed, with skepticism about their availability by 2023. Users mention Minoxidil, finasteride, and hair transplants as current treatments.

community Innovative hair loss treatment can restore 90% of lost hair

in Research/Science 885 upvotes 1 week ago

A new hair loss treatment using dermal exosomes can restore up to 90% of lost hair in mice. Users discuss potential human trials and compare it to Minoxidil and Finasteride.

community The Big Fat Layer II

in Research/Science 26 upvotes 3 years ago

Hair loss treatment should target dermal white adipose tissue (DWAT) to restore hair follicles. Potential remedies include tocopherol (vitamin E), botox, rosiglitazone, niacin, kojyl cinnamate esters, and ADP355.

community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found

in Research/Science 47 upvotes 1 year ago

The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.

community Novel effect of sildenafil (cialis) on hair growth

in Research/Science 21 upvotes 2 years ago

Sildenafil (Viagra) shows potential for hair growth by enhancing dermal papilla cell proliferation and stimulating perifollicular vessel formation. Users discuss the possibility of using Cialis (tadalafil) similarly, noting its benefits and side effects.

community Han Bio claims success at Hair Multiplication

in Research/Science 18 upvotes 3 years ago

Han Bio claims success in hair multiplication using dermal papilla cells. Treatments discussed include Minoxidil, finasteride, and RU58841.

community Shiseido filed for this patent in May 2019. Let's get some big brain discussion on this.

6 upvotes 4 years ago

The conversation discusses a patent filed by Shiseido for cloning Dermal Papilla (DP) cells to treat hair loss. The method involves using viral vectors to maintain the cells' growth-inducing properties, differing from Replicel's approach with Dermal Sheath Cup (DSC) cells.

community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

in Research/Science 743 upvotes 1 year ago

A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

community Epibiotech will now offer off-the-shelf allogeneic hair multiplication treatment in South Korea

in Research/Science 78 upvotes 2 years ago

Epibiotech will offer off-the-shelf allogeneic hair multiplication treatment in South Korea, using dermal papilla cells from donors to grow hair in balding areas. This method is cheaper and less invasive than traditional hair transplants.

community Vitamin C and hair growth PH levels

in Product 34 upvotes 2 years ago

The conversation is about using vitamin C and Magnesium L-Threonate for hair growth by reducing DHT binding to dermal papilla cells. The original post about vitamin C's pH levels and sebum control was possibly removed by a moderator.

community Anyone Try Microneedling with Exosomes/AAPE?

in Microneedling 2 upvotes 2 years ago

User asks where to purchase exosomes/AAPE for microneedling hair loss treatment. Links to research on hair regeneration therapy, stem cell therapy, exosome therapy, and dermal exosomes provided.

community 3 yrs after transplant and massive thinning

in Transplants 24 upvotes 3 years ago

User experienced hair loss after weight lifting, had a successful hair transplant, but later faced significant thinning. Current treatment includes finasteride, minoxidil, dermal rolling, and supplements.

community The Big Fat Layer / Remedies: Cetirizine

in Treatment 11 upvotes 3 years ago

Treating hair loss with various remedies, such as Cetirizine and the Big3 complex (minoxidil, finasteride, and RU58841), which have properties like adipogenic, anti-fibrotic and anti-inflammatory. References to research studies are also included.

community Seriously confused about minoxidil's method of action

in Minoxidil 6 upvotes 2 years ago

The conversation discusses confusion about how Minoxidil promotes hair growth compared to other substances like Menthol, which have similar actions. The user mentions personal positive results with peppermint oil extract and is currently trying L-citrulline for its vasodilation effects.

community Oxytocin, empathy, hair, and cinnamon

in General 87 upvotes 1 month ago

Low oxytocin levels in hair are linked to reduced empathy and may affect hair growth. Cinnamic acid can promote hair growth by activating oxytocin receptors.

community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

in Research/Science 14 upvotes 3 months ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.

community AGA responded to steroid shots? Biopsy wrong? Please help!

in Female 2 upvotes 4 months ago

A woman with AGA is using spironolactone, dutasteride, finasteride, oral minoxidil, bicalutamide, and anti-androgenic birth control but still experiences worsening hair loss. Steroid shots temporarily stop her hair shedding, leading her to question her biopsy results.

community Do we have an agreed upon consensus on the best microneedling length?

in Microneedling 9 upvotes 5 months ago

A video suggests 0.6mm microneedling is more effective for hair regrowth than 1.2mm, as it causes less trauma to stem cells. People commonly believe 1.5mm is best, but this may vary based on individual factors.

community Possible topical option for preventing BDNF-related hair loss

in Research/Science 7 upvotes 11 months ago

The conversation discusses hair loss linked to BDNF-increasing nootropics like Semax and Lions Mane. Suggested topical treatments include capsaicin, beta-glucan, and ginseng to counteract TGF-B activation.

community Surprisingly thorough study on He-Shou-Wu/Fo Ti

in Research/Science 14 upvotes 1 year ago

He Shou Wu (Fo Ti) extract was found to prolong the hair growth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.

community Does melatonin dissolve in isopropyl alcohol

in Technology 8 upvotes 1 year ago

The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.

community Tropoelastin injections + verteporfin?

in Research/Science 12 upvotes 1 year ago

The use of tropoelastin injections and verteporfin for hair transplant recipients to help regrow donor area hairs, as well as research done on tropoelastin injections restoring elastin in scarred heart tissue and skin. There are discussions about why it is taking so long to get cosmetic mass produced tropoelastin injectables on the market.

community HairClone: Good info from their site

in Technology 10 upvotes 2 years ago

HairClone aims to rejuvenate miniaturizing hair follicles through follicle banking and cell expansion, with treatments potentially available in the UK by 2022. The process involves extracting, storing, and cloning hair follicles, but full regenerative treatments will take many years to develop.

community September 2021 update from Dr. Kang-Yell Choi [Korean "cure"]

in Research/Science 32 upvotes 3 years ago

Dr. Kang-Yell Choi's company, CK Regeon, is developing a drug called KY19382 for hair regeneration, which involves creating fine wounds to activate stem cells. The drug is in the formulation development stage, targeting markets like the US and Korea.

community Han Bio Planning Hair Multiplication Trial This Year?

in Technology 6 upvotes 3 years ago

Han Bio plans to start clinical trials for a new hair multiplication technology this year, which could significantly reduce the cost and time of hair transplantation. The technology uses a single hair strand to cultivate enough cells for 30,000 hair strands.

community Progress Post (115 Days): 5% Min Topical/Topical Fin/Dermapen

in Progress Pictures 40 upvotes 4 years ago

A user shared their 115-day progress in treating hair loss using 5% Minoxidil, topical Finasteride, biotin, microneedling, and collagen peptides. They reported visible improvement and no side effects from topical Finasteride, unlike the oral form.

community redensyl - follicle stem cell activator any experiences?

in Question 8 upvotes 7 years ago

A Swiss product called Redensyl, which is supposed to target hair follicle stem cells and has recently been marketed in Europe. The post inquires if anyone has had any experience with the product.

community CRISPR Is Curing People Right Now. Genetic Hair Loss is Next?

in Technology 107 upvotes 1 week ago

CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.