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GlossaryCross-Linking

chemical bonds form between polymer chains, enhancing material properties

Cross-linking refers to the process where chemical bonds are formed between different polymer chains, creating a network-like structure. This can increase the strength, stability, and rigidity of materials. In biological contexts, cross-linking can affect the properties of proteins and other macromolecules, influencing their function and interactions.

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community For those of you who are getting facial skin side effects (aging, dark circles) from minoxidil, try this, it helped me.

in Minoxidil 13 upvotes 3 years ago

The conversation provides tips to reduce facial skin side effects from Minoxidil, such as changing pillowcases, sleeping on the back, careful application, hydration, and taking breaks. One reply suggests that alcohol in Minoxidil formulations, not Minoxidil itself, may cause skin aging.

community Minoxidil and skin aging worry – which prevention methods (platelet rich plasma, microneedlig, mesotherapy, stem cells, co2, ultherapy, …)

in Chat 4 upvotes 1 year ago

User started minoxidil, noticed forehead lines and dark circles, and asked for non-invasive skin aging prevention methods. Another user suggested using tretinoin and hyaluronic acid for long-term benefits.

community I am actually regrowing my hairline without minoxidil or finasteride (mechanical stimulation)

127 upvotes 6 years ago

Regrowing hairline without the use of Minoxidil or Finasteride, and instead using mechanical stimulation such as Derma Roller, Nizoral, Zinc Pyrithione, Scalp Massage, Scalp Exercise, Fish Oil and other topical solutions. It is cautioned that there are risks associated with not using medically-prescribed treatments, but it is suggested to consider mechanical stimulation in addition to those prescribed treatments.

community Countering oral minoxidil side effects by taking collagen supplements?

in Minoxidil 16 upvotes 2 months ago

Oral minoxidil may deplete collagen, potentially causing skin aging. Users discuss whether taking collagen supplements can counteract this effect.

community Does whey protein and creatine aggravate hair loss?

in Research/Science 77 upvotes 8 months ago

The conversation discusses whether whey protein and creatine worsen hair loss. Some users report hair loss with creatine use, while others do not; opinions on whey protein's effects are mixed. Treatments mentioned include PRP, minoxidil, and finasteride.

community Nandrolone Replacement Therapy

in Treatment 41 upvotes 1 year ago

A user discusses starting nandrolone replacement therapy to stop hair loss and improve hair health, noting its benefits over finasteride. They report halted hair loss, improved skin, increased muscle, and a calm mood after three weeks.

community DHT and 5AR respect post, it's importance within the brain

in Research/Science 109 upvotes 5 months ago

The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

community How to BECOME a RESPONDER to Fin/Dut if you are not responding

in Finasteride/Dutasteride 308 upvotes 1 year ago

The conclusion of this conversation is that the user "DuckSeasonCamelSeasn" found that consuming grapefruit juice prior to taking finasteride or dutasteride helped them become a responder to the medications and regain hair growth. However, there are warnings about potential risks and interactions with other medications, so caution should be exercised.

community A Nuanced Look at Microdosing Topical Finasteride

in Finasteride/Dutasteride 85 upvotes 8 months ago

The conversation discusses using a low dose of topical finasteride to achieve hair benefits with minimal systemic exposure. Users share experiences and opinions on dosing, systemic buildup, and side effects of both topical and oral finasteride.

community What Works to Restore Hairloss for Cis-Males? Not Much

in Treatment 20 upvotes 4 years ago

Hair regrowth treatments for cis-males include Minoxidil, Finasteride, and RU58841. Estrogen and testosterone blockers can help restore hair loss but may not suit everyone.

community First bottle of Morr-F arrived. Wish me luck, and an introduction.

11 upvotes 5 years ago

A user discusses their experience with hair loss and treatments, including minoxidil, micro needling, rosemary oil, dietary supplements, and topical finasteride (Morr-F). They emphasize the impact of lifestyle on hair health and express hope for improvement with the new treatment.

community Can’t do finasteride. Does this automatically cross out Pyrilutamide?

in Research/Science 3 upvotes 1 year ago

Hair loss discussion includes finasteride intolerance and questioning if Pyrilutamide is an alternative. Pyrilutamide not commercially available, but may be tolerable if approved since it's not a 5aR inhibitor.

community How come Dut doesn’t cause more brain problems than fin if it inhibits Type 1 5AR?

in Finasteride/Dutasteride 22 upvotes 1 month ago

Dutasteride and finasteride have similar risk profiles despite Dutasteride blocking more types of 5AR in the brain. Some users report no mood issues with either drug, and it is suggested that Dutasteride's larger molecular size may limit its ability to cross the blood-brain barrier.

community Has anyone had issues on finasteride that resolved after switching to dutasteride?

in Chat 12 upvotes 1 year ago

Hair loss discussion includes finasteride issues resolved by switching to dutasteride. Specific treatments mentioned: Minoxidil, Finasteride, and RU58841.

community Great work done by the doctor (Hair transplant) Toronto Canada

in Progress Pictures 510 upvotes 3 months ago

A user shared progress pictures of a hair transplant done in Toronto, Canada. The conversation includes comments on the appearance of Antonio Conte, with some suggesting he looked better after shaving his head.

community I wanted to thank this sub for helping getting my hair back

in Progress Pictures 1709 upvotes 3 months ago

A user shared progress pictures showing hair regrowth after using 1mg finasteride daily, minoxidil foam twice daily, and dermarolling once a week for a year. Some commenters are skeptical about the authenticity of the before and after photos, joking about changes in appearance and questioning if it's the same person.

community Balding turned me into a Norwood mentalist

in Chat 253 upvotes 4 months ago

The conversation revolves around how balding has made the original poster and others hyper-aware of other men's hairlines, often judging the severity of their hair loss and whether they've had treatments like hair transplants, minoxidil, or finasteride. Some participants express a need for therapy due to their obsession, while others joke about their newfound "expertise" in assessing hair loss.

community 7 months update (min/fin) change to dut?

in Progress Pictures 88 upvotes 5 months ago

The user has been using finasteride and minoxidil for 7 months, seeing thicker hair but no temple regrowth, and is considering switching to dutasteride. Another person suggested trying microneedling on the temples before changing medications.

community Ru with gloves because of Systemic absorption?

in Research/Science 10 upvotes 7 months ago

The conversation is about whether to use gloves when applying 5% RU58841 to avoid systemic absorption and if washing hands with water is sufficient. Users question the concern, noting it is applied to the scalp.

community Is there any Noticeable difference? Natural approach.

in Is this regrowth? 9 upvotes 8 months ago

The conversation discusses a natural approach to hair loss treatment using rosemary, peppermint oil, derma roller, pumpkin seed oil, and saw palmetto. Commenters note a slight or minor difference in hair growth.

community 22M Exact three months of medication. Dut(0.5mg/day)+minox(2 times a day)+vitamin D (60k/week)

in Progress Pictures 326 upvotes 2 years ago

User took Dutasteride, Minoxidil, and Vitamin D for hair loss treatment and saw improvement in 2 months. Vitamin D deficiency played a role in recovery.

community CB-03-01 supposed hair loss cure

in Treatment 9 upvotes 3 years ago

The conversation discusses why CB-03-01, a potential hair loss treatment, isn't widely discussed despite evidence of its effectiveness and safety. Some users mention other treatments like melatonin, procianidin b2, and RU58841, debating their effectiveness and safety.

community “Fluridil – As Good As RU58841 Without The Side Effects!?” —— anyone here on fluridil?

in Technology 21 upvotes 3 years ago

Treatments for hair loss, such as Minoxidil, finasteride, RU58841 and Eucapil; the legitimacy of RU58841 products; and safety concerns related to using RU58841.

community Any early Kintor's KX-826 experiences?

in Research/Science 6 upvotes 6 days ago

The conversation is about experiences with Kintor's KX-826 for hair loss, specifically regarding side effects. Some users reported side effects from grey market versions, questioning their authenticity.

community Looking to make my own 2-Deoxy-D-ribose. Any science bros can give advice?

in Research/Science 2 upvotes 1 week ago

A user is making a 2-Deoxy-D-ribose solution and asks if it can be put into an oil instead of a gel, considering adding hydrocortisone and retinoic acid. They seek advice on the best carrier oil for hair growth.

community Haircafe on why microneedling is bad for hair growth

in Microneedling 147 upvotes 1 week ago

Microneedling combined with minoxidil and finasteride shows significant hair regrowth, though opinions on its effectiveness vary. Some users report substantial benefits, while others highlight the need for more research and consistency in application.

community 5 months of daily using finasteride and minoxidil

in Progress Pictures 837 upvotes 2 weeks ago

User shared progress after 5 months of using finasteride, minoxidil foam, and weekly derma rolling. Positive feedback highlights increased hair count and thickness.