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Did you mean cAMP response element-binding protein?

Glossary cAMP response element-binding protein

regulates gene transcription in response to cellular signals

cAMP response element-binding protein (CREB) is a cellular protein that binds to specific DNA sequences called cAMP response elements, thereby regulating the transcription of certain genes. It plays a crucial role in various cellular processes, including the growth and survival of cells, by responding to hormonal signals and other external stimuli.

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community So what’s really the deal with dutasteride hairline ruining claims?

in Finasteride/Dutasteride 72 upvotes 3 years ago

The potential effects of dutasteride on hair loss, with some users reporting it improved their hairline while others experienced worsened hair loss or shedding. Other treatments discussed include minoxidil and finasteride, as well as RU58841.

community DHT is NOT very important for adults, is it?

124 upvotes 4 months ago

A user experienced negative side effects, including low libido and lack of motivation, after using finasteride for hair loss and felt better after stopping it. Others shared similar experiences with finasteride and dutasteride, while some reported no side effects, showing varied individual responses.

community Those that got rekt by Dut did you end up recovering?

in Finasteride/Dutasteride 48 upvotes 1 year ago

Some users experience worsening hair loss with dutasteride, while others improve after initial shedding. Many switch back to finasteride due to better results or fewer side effects, often using minoxidil and topical treatments.

community Major dutasteride hairline recession

4 upvotes 4 weeks ago

The user experienced hairline recession after switching from finasteride to dutasteride and increasing the dosage. They plan to start using oral minoxidil and are advised to be patient as shedding is expected during the transition.

community I think this is my stop, gentlepeople. So long and thanks for all the data 👋

2264 upvotes 1 year ago

A user shared their successful experience with hair regrowth and transitioning from male to female using minoxidil, finasteride, Nutrafol, microneedling, and hormone replacement therapy (HRT). They expressed gratitude for the results and encouraged others to explore treatments that align with their personal goals.

community Two of the most attractive girls I know are with NW7 guys

in Chat 319 upvotes 1 year ago

Bald men can still attract partners, as personality and confidence often outweigh hair loss. Treatments like finasteride and minoxidil are used, but self-acceptance and personal satisfaction are key.

community Guys on oral dut AND oral minox, what has been your experience so far?

in Chat 18 upvotes 2 years ago

Users discussed their experiences with oral minoxidil and dutasteride for hair loss. Most reported positive results, including hair regrowth and improved hair quality, with minimal side effects.

community 1 year on Fin 1 mg. Switching to .4 mg Dut and oral 1.25 mg min

449 upvotes 3 years ago

User shared 1-year progress on Fin 1 mg, switching to 0.4 mg Dut and oral 1.25 mg Min. Good results with Fin, biotin supplement, and biotin shampoo; trying Dut and oral Min for potential better results.

community Anagenic announces the launch Pyrilutamide on their website. Are you excited ?

79 upvotes 4 years ago

The launch of Pyrilutamide as a potential hair loss treatment, with people discussing whether it is better than treatments like finasteride and minoxidil. Some participants have also discussed the risks associated with importing drugs from China.

community 18M 8 months progress 40mg daily dut stack

in Progress Pictures 112 upvotes 1 year ago

An 18-year-old is using a high-dose hair loss treatment with 40mg daily dutasteride, finasteride, minoxidil, tretinoin, and topical bicalutamide. Despite health risk concerns, especially liver issues, they report hair regrowth progress and intend to continue the regimen.

community Why Fin/Dut Isn't Working for You GPR133: a new hairloss mechanism + Steroid Hair Loss Deep Dive

6 upvotes 1 month ago

Hair loss may be linked to the GPR133 receptor, independent of the androgen receptor pathway. Treatments like finasteride, dutasteride, minoxidil, RU58841, and KX-826 show varying results, with hair loss persisting due to high testosterone and GPR133's role.

community Everything you ever wanted to know about Pelage Pharma's PP405: how it works and what to expect

126 upvotes 2 months ago

PP405 may encourage earlier hair growth and slightly increase visible hair count but does not reverse hair follicle miniaturization in male pattern baldness. It does not address damage to the dermal papilla or broken Wnt signaling.

community Hair regrowth without drugs (99% natural) 25M

528 upvotes 3 months ago

A user shared their experience with hair regrowth using supplements like NAC and DIM, and briefly using minoxidil with microneedling. They reported some improvement in hair density, but the community questioned the effectiveness compared to traditional treatments like finasteride.

community Been on min+fin for 2 years, only gotten worse. B/A pics included

in Chat 88 upvotes 7 months ago

The user experienced worsening hair loss despite using finasteride and topical minoxidil for two years and is considering oral minoxidil and dutasteride. Suggestions include microneedling, stress management, and alternative treatments like topical finasteride or ketoconazole shampoo.

community The guys at /bald are allergic to hair regrowth

103 upvotes 11 months ago

Some embrace baldness, while others promote treatments like minoxidil and finasteride. Opinions differ on accepting baldness versus pursuing hair regrowth.

community Can't believe I've slept on microneedling for so long.

in Microneedling 584 upvotes 1 year ago

Microneedling with minoxidil and finasteride greatly improves hair regrowth. Using 0.5mm depth every other day boosts minoxidil absorption without side effects.

community Stop Complaining about Creatine. You're just fixated on shedding.

73 upvotes 1 year ago

Creatine is unlikely to cause hair loss as it does not raise DHT levels. Hair loss is more likely due to genetics, medications, or lifestyle changes.

community Ultimate Stack without nuking your gender (you'll go broke)

86 upvotes 1 year ago

A hair loss treatment plan includes finasteride, dutasteride, RU58841, pyrilutamide, minoxidil, and microneedling to inhibit DHT and promote hair growth. It also recommends supplements like Reishi and Lion’s Mane mushrooms, and a shampoo with ketoconazole, caffeine, and melatonin.

community Dental technician is convinced that he has found the cause of pattern hair loss

314 upvotes 2 years ago

A dental technician claims malocclusion causes pattern hair loss due to poor scalp circulation. Users debate this, noting treatments like finasteride, minoxidil, and microneedling focus on DHT and blood flow.

community Should I get transplant #4 or just shave my head?

in Transplants 171 upvotes 2 years ago

A 36-year-old considering a fourth hair transplant is advised to either shave his head or use a hair system due to poor results from previous transplants and late medication use. He plans to consult top surgeons and adjust his current treatments, including finasteride and minoxidil.

community This is the best time in human history to be fighting hair loss

195 upvotes 4 years ago

This conversation discusses the advancements in treatments for hair loss, including finasteride, dutasteride, minoxidil and new promising treatments such as pyrilutamide and verteporfin. Other treatments discussed were taking minoxidil orally, tretinoin to turn non-responders into responders and microneedling to further boost growth.

community Dutasteride (.5mg) is some strong stuff!

54 upvotes 4 years ago

User switched from finasteride and minoxidil to dutasteride, experienced side effects, then took dutasteride once a week with improved hair density. Another user had success with daily dutasteride, while one had no results from topical dutasteride.

community Transient and Permanent Effects of Finasteride Use

158 upvotes 4 years ago

Potential side effects of 5AR inhibitors like finasteride and dutasteride. Users debate risks, benefits, and personal experiences with these hair loss treatments.

community CURCUMIN - Effect on Androgens, Testosterone, DHT - A Brief Review of the Literature

2 upvotes 5 years ago

community Gains or growth? Three months in

in Is this regrowth? 146 upvotes 1 year ago

The user is using topical minoxidil twice daily for hair regrowth and is hesitant to use finasteride due to concerns about hormonal effects. The conversation includes mixed opinions on the effectiveness of the treatment and suggestions to use a DHT blocker for better results.

community 1 year of minoxidil no sides - hows my collagen?

18 upvotes 6 years ago

A user shared progress pictures after one year of using minoxidil with no side effects, asking about their collagen. Another user commented on the genetic aspect of hair loss.

community Can you take something like Spiro or even Estradiol if already on low dose TRT to regrow hair?

3 upvotes 1 year ago

The conversation discusses using treatments like dutasteride, minoxidil, spironolactone, and estradiol for hair regrowth while maintaining muscle mass. Concerns include potential side effects like gynecomastia and muscle loss, with suggestions to balance hormone levels carefully.

community Temple regrowth, 5 months on fin + min

in Progress Pictures 233 upvotes 6 months ago

A trans man shared his 5-month progress using finasteride and minoxidil for temple regrowth, noting slow but steady results. Despite some negative comments, he received support and encouragement from others, with advice to start treatment early for best results.

community Read before embarking on your hair recovery journey

in Treatment 207 upvotes 1 year ago

Consult a doctor before starting treatments like minoxidil and finasteride, as underlying issues like vitamin D deficiency can affect hair loss. While some believe androgenic alopecia is the most common cause, addressing all potential causes can lead to better results.

community Im still very very afraid of a possible ban of Finasteride and dutasteride in the EU

in Finasteride/Dutasteride 38 upvotes 1 year ago

There is concern about a potential ban on finasteride and dutasteride in the EU, with users discussing the impact on hair loss treatment. Some suggest alternative treatments or express skepticism about the likelihood of a ban.