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    Did you mean c-Jun N-terminal kinase?
    Glossaryc-Jun N-terminal kinase

    regulates cellular stress responses and apoptosis

    c-Jun N-terminal kinase (JNK) is a type of protein kinase that plays a crucial role in regulating various cellular processes, including inflammation, cell growth, and apoptosis (programmed cell death). It is activated in response to stress signals, such as UV radiation or cytokines, and can influence gene expression by modifying the activity of specific transcription factors like c-Jun.

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      community Fats on your Head to Stop Hair Loss?

      in Research/Science  137 upvotes 8 months ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 2 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Topical Minoxidil is a pain in the ass for diffuse thinners

      in Minoxidil  95 upvotes 1 year ago
      Topical minoxidil being a difficult product to apply, with users considering finasteride, RU58841, and oral minoxidil as alternative treatments for diffuse thinning hair. Other advice includes shaving the head in the first 3 months of using minoxidil and finding ways to apply it without saturating the hair.

      community C’est terrible - at my wits end

      in Female  445 upvotes 11 months ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

      community Vitamin C and hair growth PH levels

      in Product  34 upvotes 2 years ago
      The conversation is about using vitamin C and Magnesium L-Threonate for hair growth by reducing DHT binding to dermal papilla cells. The original post about vitamin C's pH levels and sebum control was possibly removed by a moderator.

      community Vitamin c serum after dermarolling.

      in Treatment  3 upvotes 6 years ago
      Using Vitamin C serum after dermarolling may help with healing and hair health. The safety of additional ingredients like Glycerin, Propylene Glycol, Phenoxyethanol, Sodium Benzoate, and Sodium Metabisulfite in hair regrowth is questioned.

      community the post about vitamin c and pH levels is legit.

      in Update  13 upvotes 2 years ago
      Using vitamin C in shampoo to adjust pH levels can improve hair health and reduce oiliness and dandruff. The user mixed vitamin C powder with conditioner, achieving positive results.

      community Been now 15 months on treatment Time for hair transplant? (1.25 oral finas + minox twice + oral zinc and vitamin c + caféine + microneedling every 15 days at 0.5 to 1mm)

      in Is this regrowth?  116 upvotes 1 year ago
      A user's 15-month experience with oral finasteride, minoxidil, zinc and vitamin C, caffeine, and microneedling as treatments for hair loss, which has yielded impressive results. Suggestions were made to stack a topical DHT blocker with the finasteride or increase the microneedling regimen, and it was suggested to re-evaluate at the two year mark.

      community Supplements for hair growth (Alcoholics, Smokers; and Gym Goers)

      in Treatment  6 upvotes 4 months ago
      A user shared their experience with hair loss and recommended supplements like magnesium, vitamin D, vitamin C, zinc, iron, and protein, along with using a dermaroller. They noted benefits such as accelerated fat loss, muscle growth, better digestion, increased testosterone, and improved hair and skin quality.

      community 3 months on Fin/Min + Vitamins

      in Progress Pictures  510 upvotes 7 months ago
      A user shared their positive experience with hair regrowth after 3 months using finasteride, minoxidil, and vitamins such as biotin, B5, B6, and C. They took 1.1 mg of oral finasteride, experienced a shedding period initially, and emphasized the importance of consistency.

      community Guys stay consistent with your routine!

      in Progress Pictures  607 upvotes 8 months ago
      A user shared progress pictures showing hair growth after 5.5 and 8 weeks of using Minoxidil twice daily, oral Finasteride once daily, Vitamin C once daily, derma stamping twice weekly, and Nizoral shampoo three times per week. Some replies express skepticism, while others share their own experiences and advise moderation in treatment.

      community One Month on Topical Fin and Min Experience

      in Update  10 upvotes 9 months ago
      A 27-year-old male started using topical finasteride (0.25%) and minoxidil (5%) once daily, along with supplements like zinc, magnesium, biotin, and vitamins C and D. After initial concerns about side effects, he experienced temporary ED and shedding but now feels better and has no regrets about starting the treatment.

      community Nutritional factors to check for apart from DHT ?

      in Chat  11 upvotes 1 year ago
      The conversation is about identifying nutritional factors that should be checked and supplemented to address diffuse hair loss, including Vitamin D, Biotin, Vitamin C, Vitamin B, Iron, Zinc, Protein, and Omega-3. No specific treatments were mentioned.

      community There's a guy called Dr. Berg on YouTube who recommended a bunch of supplements for hair health and preventing hair loss. I wrote them all down. Before I buy, can anyone tell me if anything here is BS?

      in Question  9 upvotes 5 years ago
      A user asked about Dr. Berg's recommended supplements for hair health, including Vitamin C, trace minerals, Omega 3, collagen, silica, B-vitamins, stinging nettle root, B6, B2, copper, and Vitamin D. Responses advised against following Dr. Berg, labeling him a quack, and suggested that only stinging nettle root might help with DHT, while the rest are only beneficial if deficient.

      community 5 month results on the big 4 (Fin/Min/Niz/Derma).

      in Finasteride  24 upvotes 5 years ago
      The user shared their positive 5-month results using finasteride, minoxidil, derma rolling, and supplements like biotin, zinc, iron, and vitamin C. They provided before and after photos and mentioned applying minoxidil even when derma rolling.

      community Is this regrowth. Semi natural approach.

      in Is this regrowth?  6 upvotes 10 months ago
      The conversation discusses a hair loss treatment regimen that includes scalp massage, derma rolling, saw palmetto, rosemary, peppermint oil, pumpkin seed oil, and various supplements like vitamins C and D, multivitamins, biotin, collagen, and fish oil. The user is asking if the treatment has led to hair regrowth.

      community Whats best vitamins and supplements before and after hair transplant?

      in Transplants 10 months ago
      The user's first hair transplant failed, and they are preparing for a second one. They are considering whether to continue multivitamins and B complex before the surgery, and are asking for advice on supplements to take for hair loss that do not include DHT blockers, finasteride, minoxidil, or high-dose biotin, and are contemplating iron, folic acid, vitamin C, and NAC for before and after the surgery.

      community what are the best multivitamins for hairloss?

      in Finasteride/Dutasteride  53 upvotes 1 year ago
      The conversation discusses which vitamins to take alongside 0.5mg finasteride for hair loss, with suggestions including a multivitamin, iron, zinc, B12, vitamin D, Nutrafol, collagen, vitamin C, saw palmetto, and magnesium. Nutrafol is noted for its benefits but also criticized for containing too much biotin.

      community Nothing's working, I feel depressed, also hopeless for the first time

      in Update  102 upvotes 2 years ago
      A user's experience with hair loss treatments, including Finasteride, Minoxidil, Nizoral Shampoo, Rosemary Oil, Vitamin D, Biotin, Vitamin C, Zinc and Dermarolling, that have not been successful over the past 14 months. Other users gave advice on how to cope with the issue, such as exercising, changing mindset, and shaving their head.

      community My nuclear protocol (scary but very effective)

      in Treatment  77 upvotes 2 years ago
      A hair loss treatment protocol involving topical and oral medications such as Minoxidil, RU58841, Finasteride, Dutasteride, Melatonin, Zinc, Vitamin B6, NAC, Caffeine, Biotin, Ginseng, and Semen; other treatments including Microneedling, Laser Helmet, Nizoral shampoo, Scalp Massage and supplements like Vitamin C, Vitamin D, Fish Oil, and Biotin; and the potential side effects of using this protocol.
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