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GlossaryBrain-Derived Neurotrophic Factor

protein supporting neuron growth and survival in the brain

Brain-Derived Neurotrophic Factor (BDNF) is a protein that plays a crucial role in the growth, maintenance, and survival of neurons in the brain. It is essential for cognitive functions such as learning and memory, and it also supports the health of existing neurons while encouraging the growth of new ones.

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community DHT and 5AR respect post, it's importance within the brain

in Research/Science 109 upvotes 5 months ago

The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

community Scientific Review: Saw Palmetto is not effective for treating hair loss and does not inhibit DHT to the extend that most people think. Anti-Hair loss claims are invalid.

in Research/Science 34 upvotes 2 years ago

Saw Palmetto is not effective for hair loss treatment and is not a recommended alternative to finasteride due to its inability to significantly inhibit DHT.

community Ultimate DHT/finasteride microdosing graph to replace the commonly one referenced on forums

in Finasteride/Dutasteride 208 upvotes 3 years ago

Hair loss treatments, specifically, discussing the effectiveness and side effects of finasteride, minoxidil, and RU58841 in various microdoses. It also includes an updated graph which provides information on how different doses affect DHT levels, scalp skin and serum androgen levels, as well as hair count.

community Would there be ANY reason to still take 5AR inhibitors if pyrilutamide does what is intended?

in Research/Science 18 upvotes 2 years ago

A potential new treatment for hair loss, Pyrilutamide, and the discussion of whether or not people should still be taking traditional treatments like Minoxidil and Finasteride with it.

community Found it. Sulforaphane, a phytochemical in broccoli sprouts, promotes hair growth (60% regeneration in mice) by accelerating the degradation of DHT.

110 upvotes 7 years ago

Sulforaphane, found in broccoli sprouts, promotes hair growth by degrading DHT. Users discuss its potential benefits and joke about unconventional application methods.

community Damn, the trash hormone DHT was losing so hard it pulled the "old social media post" card

in Chat 195 upvotes 3 months ago

The conversation is about hair loss treatments, including minoxidil, finasteride, dutasteride, tretinoin, stemoxydine, adenosine, castor oil, baicalin, and bimatoprost. The user shares their nightly and morning routines and discusses the role of DHT in hair loss.

community Dutasteride SAVES your hair follicles: MAJOR BS on people who say it destroyed their hair permanently.

in Finasteride/Dutasteride 156 upvotes 8 months ago

The conversation discusses the effectiveness of hair loss treatments, specifically finasteride and dutasteride. The conclusion is that dutasteride significantly reduces DHT levels and may be more effective than finasteride for long-term hair retention, with some users reporting personal experiences and side effects.

community Why is dht bad for scalp hair but good for hair on the rest of body?

in Satire 109 upvotes 1 year ago

The conversation discusses why DHT (dihydrotestosterone) negatively affects scalp hair but promotes growth elsewhere on the body. Various opinions include genetic predispositions, differences in hair follicle reactions to DHT, and the potential role of Omega-3 in reducing inflammation and promoting hair health.

community My Pyrilutamide Experience so far

in Update 79 upvotes 1 year ago

A user's experience with Pyrilutamide for hair loss, which has been successful in reversing receding hairline when part of their stack with other treatments such as Dutasteride, Minoxidil, and Ketoconazole shampoo.

community An argument for why we should take topical Dutasteride seriously

in Research/Science 86 upvotes 3 years ago

Topical Dutasteride may halt hair loss and effectively treat androgenic alopecia. Combining low-dose oral Dutasteride with topical application could maximize regrowth and minimize side effects.

community Can anyone confidently say their erections are the same on fin ?

in Chat 240 upvotes 2 months ago

The conversation discusses the impact of finasteride on sexual function, with many users reporting reduced libido and weaker erections despite continuing the treatment to prevent hair loss. Some users suggest checking hormone levels or switching to different dosages or treatments like dutasteride, while others share mixed experiences regarding the severity of side effects.

community How soon is hair clone? Next five years?!

in Research/Science 13 upvotes 2 months ago

Hair cloning is humorously discussed as always being 5-7 years away, with skepticism about its near-term availability. Gene editing to reactivate dormant follicles is suggested as a more likely solution within the next ten years.

community So it turns out Post Finasteride Syndrome was never real?

in Finasteride/Dutasteride 265 upvotes 1 month ago

Post Finasteride Syndrome (PFS) is debated, with some users reporting severe side effects from finasteride, while others believe these effects are rare or psychosomatic. Treatments discussed include finasteride, minoxidil, and RU58841.

community Watching my younger brother bald hurts so much.

in Treatment 263 upvotes 2 weeks ago

A 19-year-old is distressed about his 17-year-old autistic brother's hair loss, projecting his own insecurities despite being on finasteride and dutasteride. Replies suggest the brother might not care about balding, and the poster should address his own issues.

community 3 months into treatment... I'm I hyper responsive?

in Is this regrowth? 1202 upvotes 2 weeks ago

A 26-year-old male started minoxidil treatment for male-pattern baldness and saw significant regrowth in three months. He is considering finasteride but is hesitant due to potential side effects.

community Fin/min was honestly a miracle for me

in Progress Pictures 434 upvotes 1 month ago

A user shared progress pictures showing significant hair regrowth after using finasteride and minoxidil for six months. Other users discussed their varied experiences with these treatments and offered additional advice.

community How is it that golden era bodybuilders kept their hair while blasting gear while in the modern era most are bald? I’m convinced there’s something in our food and water causing MPB to speed up

in Satire 726 upvotes 1 year ago

The conversation is about the difference in hair loss between bodybuilders in the "Golden Era" and modern bodybuilders. Some users speculate that factors such as the types and doses of steroids used, genetics, diet, microplastics, and overall health may contribute to hair loss. Hair loss prevention medication and transplants are mentioned as potential treatments.

community A Different Take on Curing MBP

16 upvotes 5 years ago

Addressing hair loss by focusing on posture, blood flow, and craniofacial development. Methods include improving posture, cardiovascular activity, scalp massages, healthy diet, meditation, using minoxidil, and addressing craniofacial issues.

community Proof you should Start fin early

in Satire 248 upvotes 6 months ago

The conversation is a humorous discussion about hair loss, with users expressing envy towards an ancient figure who still has a full head of hair. No specific treatments are mentioned.

community How come Dut doesn’t cause more brain problems than fin if it inhibits Type 1 5AR?

in Finasteride/Dutasteride 22 upvotes 2 months ago

Dutasteride and finasteride have similar risk profiles despite Dutasteride blocking more types of 5AR in the brain. Some users report no mood issues with either drug, and it is suggested that Dutasteride's larger molecular size may limit its ability to cross the blood-brain barrier.

community Dutasteride is possibly BETTER for the brain than Finasteride

in Finasteride/Dutasteride 23 upvotes 4 months ago

Dutasteride may be better for the brain than Finasteride, potentially increasing dopamine levels and causing fewer side effects. For those switching from Finasteride to Dutasteride to prevent hair loss, it's recommended to continue Finasteride for 3-4 months while starting Dutasteride to avoid shedding due to Dutasteride's long half-life.

community Shiseido filed for this patent in May 2019. Let's get some big brain discussion on this.

6 upvotes 4 years ago

The conversation discusses a patent filed by Shiseido for cloning Dermal Papilla (DP) cells to treat hair loss. The method involves using viral vectors to maintain the cells' growth-inducing properties, differing from Replicel's approach with Dermal Sheath Cup (DSC) cells.

community Dutasteride Mesotherapy - What were your experiences like?

in Finasteride/Dutasteride 1 upvotes 4 weeks ago

User experienced severe brain fog and anxiety from oral dutasteride and is considering dutasteride injections with PRP for hair loss, while currently using finasteride and oral minoxidil. They seek others' experiences with dutasteride mesotherapy and its side effects.

community Options - Topical Dut to oral Fin?

in Finasteride/Dutasteride 2 upvotes 7 months ago

The user experienced headaches and brain fog with a topical solution containing Dutasteride, Minoxidil, Tretinoin, Fluocinolone, Latanoprost, and Caffeine. They are considering switching to oral or topical Finasteride to see if it alleviates these side effects.

community 2 years of Dutasteride. Not sure if I had proper MPB, or TE following drastic weight loss. But here it is (5 pics from then, and 6 from now).

in Progress Pictures 33 upvotes 1 year ago

User experienced hair thinning after losing 100 lbs and started Dutasteride treatment. They faced side effects like fatigue, brain fog, and insomnia but no erectile dysfunction.

community Sides from fin vs. depression from hair loss

in Finasteride/Dutasteride 16 upvotes 3 years ago

The conversation discusses the difficulty in distinguishing between side effects of finasteride (like brain fog and loss of libido) and depression caused by hair loss. Users share experiences of severe depression while on finasteride, leading some to stop the treatment despite anxiety over hair loss.

community What are the 'safer' alternatives to RU58841?

in Research/Science 2 upvotes 1 month ago

A user discusses switching from RU58841 to Pyrilutamide due to side effects like fatigue, brain fog, and elevated heart rate. They have used dutasteride, finasteride, and minoxidil, and are seeking safer alternatives.

community 6 month Fin + Min progress

16 upvotes 5 years ago

The user shared their 6-month progress using minoxidil and finasteride for hair loss, noting some brain fog and dizziness as possible side effects. They stopped derma-rolling and using nizoral shampoo, and other users commented positively on the results.

community Is getting on Dut at 21 a bad idea after taking Fin since 18?

in Chat 7 upvotes 2 months ago

A user is considering switching from finasteride to dutasteride for hair loss at age 21, worried about potential side effects on bone and brain development. Another user shared their positive experience with dutasteride, noting minimal body hair and no side effects.

community I know I'm lucky enough to reverse and keep my hair

in Progress Pictures 6 upvotes 4 months ago

The individual reversed their hair loss using oral dutasteride and topical minoxidil, and experienced side effects including low libido, tiredness, and brain fog. They started treatment at age 26 and have a high-protein diet and exercise regularly.