Search
for

    GlossaryAutoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy

    rare genetic disorder causing multiple endocrine issues, chronic fungal infections, and skin abnormalities

    Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (APECED), also known as Autoimmune Polyendocrine Syndrome Type 1 (APS-1), is a rare genetic disorder characterized by the dysfunction of multiple endocrine glands, chronic mucocutaneous candidiasis (persistent fungal infections of the skin, nails, and mucous membranes), and ectodermal dystrophy (abnormalities in the skin, teeth, and nails). It is caused by mutations in the AIRE gene, which plays a crucial role in immune system regulation, leading to the body's immune system attacking its own tissues.

    Related Terms

    Sort by

    Community Join

    30 / 148 results

      community Autoimmune disease and balding

      in Update  12 upvotes 2 months ago
      A user diagnosed with Crohn's disease is concerned it might contribute to balding. They have been using keto shampoo, finasteride, and oral minoxidil, which improved their hair but not significantly.

      community Autoimmune issue?

      in Question  2 upvotes 6 years ago
      The user experienced severe hair loss, itchy scalp, and skin issues after trying no-shampoo, and wonders if it's male pattern baldness or an immune issue. They have a history of eczema, dermatitis, and jock itch, and have tried various treatments like coconut oil, peppermint, pumpkin seed, and onion.

      community Fin/dut increase in estrogen and autoimmune diseases

      in Chat  6 upvotes 1 year ago
      The conversation discusses the link between increased estrogen and autoimmune diseases, with a focus on avoiding soy and milk. It also mentions treatments like Minoxidil, finasteride, and RU58841 for hair loss.

      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  21 upvotes 23 hours ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

      community Treating my DUPA via controlling inflammation

      in Treatment  6 upvotes 6 months ago
      The user has DUPA and suspects autoimmune activity as a cause. They have tried various treatments including finasteride, minoxidil, dutasteride, pyrilutamide, estrogel, hydrocortisone, and clobetasol, and are now seeking a long-term immunosuppressant.

      community The Truth About DUPA and Retrograde: My Research Summary

      in Research/Science  19 upvotes 2 weeks ago
      The conversation discusses the importance of scalp biopsies for diagnosing hair loss conditions like DUPA and Retrograde, which may not be just AGA. It emphasizes that treatments like finasteride and dutasteride may not work if the condition is autoimmune.

      community I bought a microscope, how does my scalp/hairs look? I've been suffering diffuse thinning and hair loss after covid and never recovered (2 yrs ago) I eat healthy, in shape and workout.

      in Progress Pictures  86 upvotes 5 months ago
      A person with hair loss since COVID-19 is considering treatments like finasteride and minoxidil but is hesitant due to potential side effects. Suggestions include visiting a dermatologist, using a ketoconazole shampoo, and considering that post-COVID hair loss might be an autoimmune response.

      community Not everyone should immediately go on Fin if they are starting to bald

      in Finasteride/Dutasteride  20 upvotes 8 months ago
      The conversation suggests that people should consult a dermatologist to understand their type of hair loss before starting treatments like finasteride or dutasteride, especially if they have autoimmune issues or low DHT. Some participants believe in starting treatment like finasteride immediately if hair loss is due to DHT, while others recommend ruling out other causes and considering minoxidil first, especially for younger individuals.

      community 17M biotin and minoxidil hair regrowth progress

      in Progress Pictures  83 upvotes 11 months ago
      A user's hair regrowth journey using biotin and minoxidil after initial treatments with Nizoral shampoo and Ketoconazole serum didn't work. The comments suggest the hair loss might not be male pattern baldness (MPB), but possibly Alopecia Areata, an autoimmune disorder, and recommend getting a second opinion and considering other treatments like corticosteroids.

      community Got a microscope camera. Here’s the difference between healthy and miniaturized hair

      in Progress Pictures  492 upvotes 2 years ago
      A user who shared progress pictures of their scalp using a microscope camera, demonstrating the difference between healthy and miniaturized hair. Various explanations for the cause of this were discussed, such as DHT build-up in scalp sebum causing an autoimmune response leading to inflammation and eventual hair loss, with some suggesting a do-it-yourself treatment involving adding ascorbic acid powder to shampoo.

      community fin 0.5 mg everday 6 months update

      in Finasteride/Dutasteride  29 upvotes 9 months ago
      The post discusses the experiences of individuals with diffuse hair thinning using finasteride, with many reporting no improvement or worsening conditions after 6 months. Various suggestions include persisting with the treatment, checking for underlying conditions, adding minoxidil for volume, adjusting dosage, and considering other potential causes like autoimmune responses and inflammation.

      community Minoxidil can prevent hair follicle miniaturization!?

      in Minoxidil  6 upvotes 3 years ago
      Minoxidil can prevent hair follicle miniaturization, not just stimulate hair growth. Finasteride and dutasteride don't work for everyone, suggesting DHT may not be the sole cause of hair loss; hair loss could be due to multiple factors, including autoimmune conditions.

      community Losing hair everywhere, idk what to do :(

       29 upvotes 5 years ago
      A 22-year-old male has been experiencing widespread hair loss for over four years, including pain and significant shedding. Treatments tried include ketoconazole shampoo, fluocinonide topical solution, biotin, ACV, and dry shampoo, but none have been effective.

      community Dont know what the hell is going on.

      in Chat  6 upvotes 1 month ago
      The user experienced rapid diffuse hair thinning for five years despite no signs of AGA or miniaturization. They tried finasteride and oral minoxidil without success and have checked thyroid, iron, and vitamin D levels.

      community The celebrated doctors that we adore so much and whose advice we hear without doubts, are only humans after all

      in Finasteride/Dutasteride  2 upvotes 5 months ago
      The user visited three dermatologists for hair loss treatment and was disappointed with their lack of thorough examination and discussion. Treatments prescribed included minoxidil, finasteride, multivitamins, ketoconazole shampoo, vitamin D3, and biotin, but the user was dissatisfied with the approach and lack of consideration for newer treatments.

      community TE turned into Scarring hairloss

      in Update  10 upvotes 5 months ago
      The user experienced hair loss due to a crash diet and later developed scarring hair loss. They are now on finasteride, oral minoxidil, LDN, Zyrtec, and Oztela to reduce scalp inflammation and promote hair regrowth.

      community Medications that cause extra hair growth

      in Research/Science  123 upvotes 10 months ago
      The post discusses the side effects of various drugs causing excess hair growth, questioning why only minoxidil is used in the hair loss industry. The conversation includes users sharing their experiences and concerns about potential side effects of these drugs, with some preferring baldness over potential health risks.

      community 1 Month Topical Minoxidil Only

      in Progress Pictures  72 upvotes 11 months ago
      The conclusion of the conversation is that the user plans to use topical minoxidil, ketoconazole shampoo, and a derma stamp for hair loss treatment. They also plan to start using finasteride in the next 2 months. Other users suggest using finasteride and a hair transplant for better results. The user appreciates the feedback and will continue posting progress.

      community Ru58841 completely got rid of my seb derm

      in Chat  6 upvotes 1 year ago
      RU58841 cured seborrheic dermatitis, oily scalp, dandruff, and scalp pain, improving hair health when combined with Minoxidil. Another user noted diet impacts their seborrheic dermatitis and that finasteride hasn't changed their condition.

      community I lost the fight against MPB at age 22 despite being on treatments.

      in Finasteride/Dutasteride  72 upvotes 1 year ago
      The user "ajsr8" shared their story of hair loss despite being on treatments. They started using finasteride in 2019 and later tried topical minoxidil, but it didn't seem to work. They also experienced side effects from other treatments. They are considering cutting off their hair and stopping the medications if there is no improvement in three months. Other users suggested trying different treatments and getting a blood test to check for underlying conditions.

      community My scalp punch biopsy results🤔?

      in Female  7 upvotes 1 year ago
      Female using Rogaine foam for hair loss had scalp punch biopsy, diagnosed with Androgenetic Alopecia (AGA). Doctor recommended starting Spironolactone 50mg.

      community To anyone that is still not seeing results on the big 3…

      in Treatment  103 upvotes 2 years ago
      User redh0t12 suggests using a derma pen for hair regrowth, as it helped them after using finasteride and minoxidil. Others discuss their experiences with various treatments, including derma rolling, oral and topical minoxidil, and finasteride, with mixed results.

      community Opinions on Scalp fibrosis and DHT?

      in Research/Science  9 upvotes 2 years ago
      The conversation discusses the theory that scalp fibrosis contributes to male pattern baldness (MPB) by increasing DHT concentration, and mentions treatments like Minoxidil. The user seeks opinions on the theory and the effectiveness of scalp massages.

      community Dermaroller or Ketoconazole? Which caused this?

      in Ketoconazole  6 upvotes 4 years ago
      User experienced hair loss after using a dermaroller, onion juice, and ketoconazole shampoo, and later started finasteride. They are unsure if the hair loss is due to the dermaroller or ketoconazole and seek advice.

      community 6 Effective Ways To Prevent Hair Loss By Home Remedies

      6 years ago
      The conversation discusses six home remedies to prevent hair loss: oil massage, aloe vera, onion juice, beetroot, and flaxseed. These methods aim to improve scalp health, promote hair growth, and reduce hair fall.