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Recent Advances in the Molecular Mechanisms Determining Tissue Sensitivity to Glucocorticoids: Novel Mutations, Circadian Rhythm, and Ligand-Induced Repression of the Human Glucocorticoid Receptor

research Recent Advances in the Molecular Mechanisms Determining Tissue Sensitivity to Glucocorticoids: Novel Mutations, Circadian Rhythm, and Ligand-Induced Repression of the Human Glucocorticoid Receptor

62 citations, August 2014 in “BMC Endocrine Disorders”

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

research A Meeting of Two Chronobiological Systems: Circadian Proteins Period1 and BMAL1 Modulate the Human Hair Cycle Clock

92 citations, September 2013 in “Journal of Investigative Dermatology”

BMAL1 and Period1 genes can influence human hair growth.

research Circadian Clock-Mediated Control of Stem Cell Division and Differentiation: Beyond Night and Day

91 citations, August 2014 in “Development”

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

research The Peripheral Clock Regulates Human Pigmentation

81 citations, October 2014 in “The journal of investigative dermatology/Journal of investigative dermatology”

Certain genes control the color of human hair by affecting pigment production.

research Timing of Expression of the Core Clock Gene Bmal1 Influences Its Effects on Aging and Survival

237 citations, February 2016 in “Science Translational Medicine”

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

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community What regimen do I need to get this hairline?

in Satire 365 upvotes 1 year ago

Discussing a regimen to improve the user's hairline, with treatments proposed including minoxidil, rectal microneedling, IV drip of minoxidil, laser removal, PRP injection, topical minoxidil, divine protein shakes, stem cell injections, and keto shampoo.

community 18 month update on fin and min

in Progress Pictures 337 upvotes 1 year ago

As it was at 1 year This conversation is about a user who has been using finasteride and minoxidil for 18 months to treat hair loss, with positive results. They have also made lifestyle changes such as the use of Hims shampoo and conditioner, gym workouts, and eating proteins on weekdays.

community Semen Analysis results: Before and after Finasteride

in Research/Science 223 upvotes 3 years ago

A man stopped taking finasteride, a hair loss treatment, to improve his fertility. His sperm count and motility increased after stopping the medication, but sperm shape did not change.

community Just started RU a month ago after being on fin and min for almost 3 years. Progress so far: My temples were pretty bare before this. Really hoping at least some of these become terminal.

in Is this regrowth? 392 upvotes 10 months ago

A user started using RU58841 a month ago after using finasteride and minoxidil for nearly three years, hoping for hair regrowth at the temples. Other users suggest vitamin B supplements and microneedling to improve hair thickness, and one mentions the possibility of a hair transplant for the temples.

community What else can I do to compliment Minoxidil?

in Update 4 upvotes 1 year ago

A user has been using minoxidil for hair loss and has seen positive results, but is seeking additional treatments to enhance its effects. One suggestion given is to use finasteride alongside minoxidil.

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