1 citations
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March 2023 in “Journal of the Turkish Academy of Dermatology”
This report suggests a possible association between temporal triangular alopecia and sebaceous nevus, and identifies a pinkish background as a new trichoscopic finding for TTA.
April 2021 in “Journal of The European Academy of Dermatology and Venereology”
This study reports no new results as it is a letter discussing associations between clinicalvariables, treatment regimens, and hair density and calibre in female androgenetic alopecia patients.
35 citations
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August 2006 in “Molecular genetics and metabolism”
This study found significant variation in tissue mutant load in individuals with the T8993G mutation, which complicates genetic counseling and may inform genotype-phenotype correlations, especially using hair bulb mtDNA analysis.
21 citations
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February 2017 in “Dermatologic surgery”
In this study, different donor and recipient site preparation techniques for melanocyte-keratinocyte suspension were associated with similar repigmentation outcomes in stable vitiligo, but efficacy varied by body site.
July 2026 in “International Journal of Advanced Research in Science Communication and Technology”
In this study, the BaldGraphFormer framework, integrating visual and clinical data, outperformed unimodal baselines in early-stage androgenetic alopecia detection, achieving an F1-score of 97.62% and macro-average AUC of 0.992, suggesting its potential to support dermatological decision-making and early intervention.
PP405 is a potential new hair loss treatment that might replace finasteride and minoxidil, but it is still in clinical trials and may not be available until 2028-2031. There is skepticism about its effectiveness, with only a 20% increase in hair density observed in some participants.
1 mg of finasteride is commonly prescribed because it is more effective for a larger number of people compared to lower doses, despite only slightly reducing serum DHT more than 0.2 mg. Serum DHT and scalp DHT are different, and 1 mg is believed to reduce scalp DHT more effectively, contributing to better hair growth results.
PP405 shows promise in hair regrowth, with 31% of participants experiencing over 20% increase in hair density after 8 weeks. Phase 3 trials are expected in 2026, with potential market availability by 2029-2031.
Laser caps are found to be more effective than 5% minoxidil for treating hair loss, and when combined with minoxidil, they are even more effective. Some users report positive results with laser treatments, while others see no change; the devices are FDA approved, but opinions on their efficacy vary.
PP405 and JXL069 are confirmed to be the same molecule, leading to disappointment due to poor hair regrowth results. Users express skepticism about the credibility of Pelage and the effectiveness of JXL069.
What do clinical trials say about the safety and effectiveness of SCUBE3 for hair regrowth?No clinical trial of SCUBE3 for hair regrowth has been registered on ClinicalTrials.gov or published, so there is no human safety or effectiveness data. The evidence is limited to one 2022 laboratory and mouse study reporting that SCUBE3 activates hair follicle stem cells through TGF-beta signalling.
Are there any clinical studies supporting follistatin as a hair loss treatment?There is no controlled human trial showing follistatin treats hair loss; the published work is mouse and laboratory biology on the activin/follistatin signalling system, plus one small 2011 phase 1 injection study of a combination product, so follistatin remains experimental and unapproved.