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Glossary Clinical Examination

thorough evaluation by a healthcare professional to assess health

A Clinical Examination, also known as a Physical Examination, is a thorough evaluation performed by a healthcare professional to assess a patient's overall health and identify any medical conditions. This process typically involves observing, palpating, percussing, and auscultating various parts of the body, as well as taking vital signs like blood pressure, heart rate, and temperature.

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Research

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research Estudo comparativo entre exames clínico, dermatoscópico e anatomopatológico em portadores de alopecia frontal fibrosante, diferenciando melasma e líquen plano pigmentoso / A comparative study between clinical, dermatoscopic and pathological examinations in patients with frontal fibrosing alopecia, differentiating melasma from lichen planus pigmentosus

February 2022 in “Brazilian Journal of Health Review”

In this study, researchers found that among women with frontal fibrosing alopecia and hyperpigmented facial lesions, most cases were diagnosed with lichen planus pigmentosus, while some were identified as melasma or drug-induced.

research Examination of Clinical and Demographic Characteristics of 14 Cases with Frontal Fibrosing Alopecia

1 citations , January 2018 in “Medical Science and Discovery”

This review examines the characteristics of frontal fibrosing alopecia in postmenopausal women, highlighting the importance of biopsy for early diagnosis and potential treatment to prevent disease progression.

research Examination of Clinical and Demographic Characteristics of 14 Cases with Frontal Fibrosing Alopecia

July 2019 in “Medical Science and Discovery”

This study retrospectively analyzed 14 postmenopausal women with frontal fibrosing alopecia, noting that 57% experienced total eyebrow loss, and all received various steroid treatments, highlighting the importance of early diagnosis to potentially delay disease progression.

Results of Clinical Examinations, Laboratory Tests, and Ultrasonography in Dogs with Pituitary-Dependent Hyperadrenocorticism Treated with Trilostane

research Results of clinical examinations, laboratory tests, and ultrasonography in dogs with pituitary-dependent hyperadrenocorticism treated with trilostane

116 citations , April 2002 in “American journal of veterinary research”

This study found trilostane to be an effective and generally safe treatment for improving symptoms in dogs with pituitary-dependent hyperadrenocorticism.

A Review of Aging and an Examination of Clinical Methods in the Assessment of Aging Skin. Part 2: Clinical Perspectives and Methods

research A review of ageing and an examination of clinical methods in the assessment of ageing skin. Part 2: Clinical perspectives and clinical methods in the evaluation of ageing skin

78 citations , September 2008 in “International Journal of Cosmetic Science”

This review outlines various clinical methods for assessing ageing skin and discusses their application in supporting the efficacy claims of anti-ageing treatments, but it reports no new clinical results.

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Community Join

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community Perifollicular Fibrosis and its role in androgenetic alopecia. Is Aminexil/Kopexil a must for anyone with AGA?

5 upvotes 4 years ago

Aminexil/Kopexil may help reduce hair loss by addressing perifollicular fibrosis in androgenetic alopecia, but it lacks the extensive clinical backing of finasteride and minoxidil. Some users find it effective, but availability and cost are issues, especially in the US where it's not FDA-approved.

community PELAGE PHASE 2 TRIALS FOR PP405 - Volunteers Needed

24 upvotes 2 years ago

PP405 is a topical gel being tested for hair regrowth in adults with androgenetic alopecia. Volunteers aged 18-55 are needed for a 16-week trial in several US locations.

community Minoxidil Sulfate makes everyone a responder

258 upvotes 1 year ago

Minoxidil sulfate is more effective than regular minoxidil, especially for those with low sulfotransferase levels or scalp sensitivity, but it is unstable unless delivered in a liposomal format. Combining minoxidil with tretinoin can enhance effectiveness, and stopping minoxidil use can lead to rapid hair loss.

community Connection between finasteride and nafld?

in Research/Science 4 upvotes 2 years ago

Finasteride may affect liver function and cortisol levels, potentially linking it to non-alcoholic fatty liver disease (NAFLD). More research is needed to understand this connection fully.

community Dutasteride Mesotherapy or Oral Finasteride

4 upvotes 5 years ago

A user is considering dutasteride mesotherapy versus oral finasteride for hair loss, with concerns about side effects. Other users share experiences with both treatments, suggesting oral finasteride as more effective and cost-efficient, while also discussing the use of minoxidil, alfatradiol, and potential side effects like gynecomastia.

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Learn

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learn Epidermal Growth Factor

learn KY19382

Are there clinical studies showing that KY19382 can regrow hair in androgenic alopecia? No clinical studies have proven KY19382 regrows hair in androgenic alopecia.

learn SCUBE3

What do clinical trials say about the safety and effectiveness of SCUBE3 for hair regrowth? No clinical trial of SCUBE3 for hair regrowth has been registered on ClinicalTrials.gov or published, so there is no human safety or effectiveness data. The evidence is limited to one 2022 laboratory and mouse study reporting that SCUBE3 activates hair follicle stem cells through TGF-beta signalling.

learn Follistatin

Are there any clinical studies supporting follistatin as a hair loss treatment? There is no controlled human trial showing follistatin treats hair loss; the published work is mouse and laboratory biology on the activin/follistatin signalling system, plus one small 2011 phase 1 injection study of a combination product, so follistatin remains experimental and unapproved.

learn Tofacitinib

What types of hair loss conditions are most commonly associated with tofacitinib use in clinical settings? Published studies link tofacitinib mainly to alopecia areata and its severe variants — as an off-label drug being studied for them, not as a cause of hair loss. The evidence is mostly small, open-label or retrospective, and relapse after stopping is commonly reported.

learn GT20029

When will GT20029 be commercially available, and are there any clinical trials on its use? GT20029 is not approved or commercially available anywhere and remains investigational. A published 12-week Phase II study in 180 Chinese men reports hair-count gains over placebo, but no long-term or Phase III data exists, so any launch is years away at best.

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