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    Glossary Chronic Wounds

    injuries that don't heal within a typical 3-month period

    Chronic wounds, also known as non-healing or persistent wounds, are injuries to the skin that fail to progress through the normal stages of healing within a predictable timeframe, typically around 3 months. These wounds can result from various underlying conditions such as diabetes, poor circulation, or prolonged pressure, and often require specialized medical treatment to promote healing and prevent complications like infection.

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    Research 10 of 1000+

    1. Cellular and molecular mechanisms of repair in acute and chronic wound healing British Journal of Dermatology · 2015 · 908 citations
    2. Macrophage Related Chronic Inflammation in Non-Healing Wounds Frontiers in Immunology · 2021 · 228 citations
    3. A Concise Review on Tissue Engineered Artificial Skin Grafts for Chronic Wound Treatment: Can We Reconstruct Functional Skin Tissue In Vitro? Cells · 2020 · 133 citations
    4. In vivo expansion and regeneration of full‐thickness functional skin with an autologous homologous skin construct: Clinical proof of concept for chronic wound healing International Wound Journal · 2019 · 38 citations
    5. Gene therapy to enhance angiogenesis in chronic wounds Molecular Therapy — Nucleic Acids · 2022 · 36 citations
    6. Biomembrane-Based Nanostructure- and Microstructure-Loaded Hydrogels for Promoting Chronic Wound Healing International Journal of Nanomedicine · 2023 · 24 citations
    7. Extracellular vesicles from hair follicle-derived mesenchymal stromal cells: isolation, characterization and therapeutic potential for chronic wound healing Stem cell research & therapy · 2022 · 22 citations
    8. Locally Delivered Umbilical Cord Mesenchymal Stromal Cells Reduce Chronic Inflammation in Long-Term Nonhealing Wounds: A Randomized Study Stem Cells International · 2020 · 14 citations
    9. Pectin Nanoparticle-Loaded Soft Coral Nephthea sp. Extract as In Situ Gel Enhances Chronic Wound Healing: In Vitro, In Vivo, and In Silico Studies Pharmaceuticals · 2023 · 10 citations
    10. Modulation of macrophage functions by ECM-inspired wound dressings – a promising therapeutic approach for chronic wounds Biological Chemistry · 2021 · 9 citations
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