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Glossary Chronic Wounds

injuries that don't heal within a typical 3-month period

Chronic wounds, also known as non-healing or persistent wounds, are injuries to the skin that fail to progress through the normal stages of healing within a predictable timeframe, typically around 3 months. These wounds can result from various underlying conditions such as diabetes, poor circulation, or prolonged pressure, and often require specialized medical treatment to promote healing and prevent complications like infection.

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Research

5 / 1000+ results

research Cellular and molecular mechanisms of repair in acute and chronic wound healing

908 citations , July 2015 in “British Journal of Dermatology”

This article reviews the cellular and molecular processes of acute and chronic wound healing, emphasizing the need for collaboration between researchers and clinicians to advance therapeutic solutions; it presents no new clinical results.

research Macrophage Related Chronic Inflammation in Non-Healing Wounds

228 citations , June 2021 in “Frontiers in Immunology”

This review discusses the role of macrophages in chronic wound healing and suggests that understanding their regulation can inform therapeutic approaches, but it reports no new results.

research A Concise Review on Tissue Engineered Artificial Skin Grafts for Chronic Wound Treatment: Can We Reconstruct Functional Skin Tissue In Vitro?

133 citations , July 2020 in “Cells”

This review discusses the modern approach of skin tissue engineering for chronic wound treatment, focusing on bioengineered artificial skin substitutes and assessing innovations in biomaterials and cell use; it reports no new clinical results.

research In vivo expansion and regeneration of full‐thickness functional skin with an autologous homologous skin construct: Clinical proof of concept for chronic wound healing

38 citations , March 2019 in “International Wound Journal”

In this study, a new cell-tissue technology using a patient's own skin to create a full-thickness skin autograft successfully treated a chronic wound larger than 200 cm², achieving complete functional skin coverage within 12 weeks and maintaining results at a 6-month follow-up.

research Gene therapy to enhance angiogenesis in chronic wounds

36 citations , August 2022 in “Molecular Therapy — Nucleic Acids”

This review discusses various gene therapy and non-viral delivery methods to promote angiogenesis for chronic wound healing, but it reports no new clinical results.

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Community Join

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community Could Finasteride theoretically induce chronic telogen effluvium?

5 upvotes 1 year ago

A user experienced continuous hair shedding for 13 months after starting finasteride, suspecting it might cause chronic telogen effluvium, and considered switching to dutasteride or stopping medication. Other users suggested that finasteride doesn't cause hair loss, recommending dutasteride for more aggressive hair loss, while some advised against stopping medication.

community From Perfect Hair to This: 2 Years of Chronic TE + Unmasked AGA.

in Treatment 5 upvotes 5 months ago

A 25-year-old is experiencing chronic telogen effluvium (TE) and androgenetic alopecia (AGA) after surgery, using finasteride, red light therapy, and supplements, and considering oral minoxidil despite heart concerns. They are unsure whether to start minoxidil before or after an upcoming surgery, which may trigger another hair shed.

community Fresh off the press: Dutasteride may cause chronic infertility

in Research/Science 643 upvotes 1 year ago

Dutasteride may cause chronic infertility by reducing semen volume and motility, with concerns about irreversible prostate fibrosis. Users consider switching to finasteride or using treatments like minoxidil and microneedling, weighing hair preservation against fertility.

community 26F Thinner hair due to vitamin deficiencies?

13 upvotes 2 years ago

A female user with chronic anemia and vitamin deficiencies is experiencing finer, straighter hair and seeks recommendations for scalp products to improve circulation and prevent potential hair thinning. She is considering growth oils but is unsure of their effectiveness.

community Suggestions?

5 upvotes 12 years ago

The user is experiencing chronic folliculitis with scalp sores and is concerned about a receding hairline. They have tried various treatments including antibiotics, Nizoral 2% shampoo, and lifestyle changes, but are seeking further advice.

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Learn

7 / 801 results

learn Follistatin

glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

learn Beta Polypeptide

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Botox

Could Botox be the unexpected solution for chronic hair shedding? Botox may help reduce chronic hair shedding by improving scalp blood flow.

learn Folic acid

Is folic acid deficiency a common cause of chronic or sudden hair shedding? Folic acid deficiency can contribute to hair shedding but is not a common cause.

learn Vitamin B12

Is Vitamin B12 helpful for both men and women experiencing chronic hair shedding? Vitamin B12 may help with hair shedding only if there is a deficiency.

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Clinics

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