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Glossary Central Centrifugal Cicatricial Alopecia

scarring hair loss starting at the scalp's crown, common in African American women

Central Centrifugal Cicatricial Alopecia (CCCA) is a type of scarring hair loss that typically starts at the crown of the scalp and spreads outward in a circular pattern. It is most commonly seen in African American women and can lead to permanent hair loss due to the destruction of hair follicles and subsequent scarring.

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Research

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Characteristics of Central Cicatricial Centrifugal Alopecia in Elderly vs. Younger Patients

research Characteristics of central cicatricial centrifugal alopecia that developed in elderly compared with younger patients

September 2018 in “Journal of the American Academy of Dermatology”

Elderly patients with CCCA were all African American with low vitamin D, but no iron or zinc deficiencies, and no hormonal imbalances compared to younger patients.

research Central centrifugal cicatricial alopecia – an approach to diagnosis and management

32 citations , November 2011 in “International Journal of Dermatology”

This article reviews central centrifugal cicatricial alopecia, focusing on its multifactorial etiology and challenges in clinical diagnosis, and calls for more research and better treatment options.

research Central centrifugal cicatricial alopecia: possible familial aetiology in two African families from South Africa

15 citations , November 2012 in “International Journal of Dermatology”

This case series observed a potential familial link in central centrifugal cicatricial alopecia (CCCA), suggesting a genetic predisposition that may be worsened by hair grooming practices.

research Central centrifugal cicatricial alopecia: Past, present, and future

75 citations , March 2009 in “Journal of The American Academy of Dermatology”

This review discusses the evolution and ongoing debate about the causes of central centrifugal cicatricial alopecia in African American women, without presenting new clinical findings.

research Central Centrifugal Cicatricial Alopecia: New Insights and a Call for Action

27 citations , September 2017 in “Journal of Investigative Dermatology Symposium Proceedings”

This article discusses central centrifugal cicatricial alopecia, noting its prevalence in women of African descent and highlighting the need for further genetic research to improve treatment options; it reports no new clinical results.

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Community Join

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community lost my hair in a single year of treatment at 20 years old

91 upvotes 2 years ago

A 20-year-old lost significant hair after one year of treatment, using minoxidil, finasteride, and later dutasteride. They are considering adding RU58841 but are advised to return to finasteride and minoxidil for a year before deciding.

community Exploring Bryan Johnson's Hair Routine In Detail

64 upvotes 2 years ago

Bryan Johnson uses a custom hair loss treatment that includes topical finasteride, minoxidil, azelaic acid, diclofenac, tea tree oil, rosemary oil, ginkgo biloba, biotin, and melatonin, which have shown varying degrees of effectiveness with minimal side effects. He also undergoes PRP and laser therapy, and has tried dutasteride mesotherapy.

community can someone help me identify these pls

in Treatment 10 months ago

The user is experiencing diffuse thinning and inflammation despite using 2.5mg dutasteride daily, ciclopirox, and ketoconazole shampoos. They are considering treatments like hydroxychloroquine and JAK inhibitors due to suspected scarring alopecia and have faced challenges in obtaining a scalp biopsy.

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Learn

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learn Centella

Got small bald circles with no warning? Centella creams might calm the area and kickstart new growth. There is no published human trial of Centella asiatica for alopecia areata or any other hair loss; the only hair-related studies are cell-culture work. Community users describe Centella creams as soothing for an irritated scalp, not as regrowth treatments, and a new bald patch needs a doctor's diagnosis first.
Ever wonder why your hair doesn’t grow back thick anymore? Maybe your scalp needs better blood flow: centella could help. There is no clinical trial of centella asiatica for hair loss and no study measuring scalp blood flow in people using it; the only hair-related evidence is a 2017 cell-culture study. Centella products are cosmetics that may soothe an irritated scalp, and the link between scalp circulation and pattern hair loss is itself unproven.

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