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research A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea

15 citations , June 2019 in “eLife”

This study identified Activin A and follistatin as key regulators of hair cell differentiation in the mammalian auditory sensory epithelium, with Activin A signaling influencing the timing and pattern of cell differentiation.

research 291 WITHDRAWN

September 2017 in “Journal of Investigative Dermatology”

Certain products and treatments can improve hair health and growth.

research Long-Term Effects of Sirolimus on Human Skin TSC2-Null Fibroblast‒Like Cells

1 citations , March 2021 in “Journal of Investigative Dermatology”

Sirolimus can reduce tumor cell size in TSC-related skin tumors, but continuous treatment is needed to maintain benefits.

research A primer for studying cell cycle dynamics of the human hair follicle

38 citations , April 2016 in “Experimental Dermatology”

This review discusses immunohistological and immunofluorescent methods for studying the human hair follicle cell cycle, reporting no new results, and suggests its potential for advancing cell cycle research.

research Immune cell regulation of the hair cycle

27 citations , January 2020 in “Experimental Dermatology”

This review discusses the role of immune cells in mammalian hair cycle control and highlights their potential relevance to human hair cycling disorders, reporting no new clinical findings.

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community Everything you ever wanted to know about Pelage Pharma's PP405: how it works and what to expect

126 upvotes 3 months ago

PP405 may encourage earlier hair growth and slightly increase visible hair count but does not reverse hair follicle miniaturization in male pattern baldness. It does not address damage to the dermal papilla or broken Wnt signaling.

community The Cure isn't 5 years away; it's already here.

in Research/Science 1005 upvotes 1 year ago

PP405 is a new topical treatment for hair loss, showing promise in trials but still requires finasteride for maintenance. There is skepticism about its effectiveness and safety, with concerns about needing finasteride to maintain results.

community 23M Couldn’t go bald for fear of my Girlfriend leaving me.

1096 upvotes 1 year ago

A 23-year-old man uses a topical spray with minoxidil, finasteride, and tretinoin for hair loss, experiencing improved hair growth but occasional heart palpitations. He worries his girlfriend might leave him if he goes bald, but commenters advise that if she would leave over hair loss, she isn't worth it.

community FINASTERIDE REVIVING ME FROM THE DEAD

927 upvotes 2 years ago

A 17-year-old user reports significant hair regrowth using 1mg finasteride daily and 5% minoxidil once daily. Other users discuss the effectiveness and age considerations of finasteride.

community Has anyone here been on finasteride for longer than 10 years? If so, have you had any major issues with the medicine please share your experience and how long you have taken the medicine.

in Treatment 112 upvotes 9 months ago

Long-term finasteride use typically slows hair loss, with some users experiencing side effects like sexual dysfunction and depression. Many users also use minoxidil and dutasteride for improved results, though individual responses vary.

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learn Stem Cell Factor

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