January 2023 in “Biocell” The study found that safflower extract may help protect human follicle dermal papilla cells from cisplatin-induced damage, suggesting its potential as an adjuvant in chemotherapy to mitigate hair follicle cell damage.
August 2025 in “Tropical Journal of Natural Product Research” This study found that mint leaf and Aloe vera serum together significantly reduced CDK1 expression, which may help prevent chemotherapy-induced alopecia in rats, although only mint serum alone reduced CDC25 expression.
14 citations
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May 2020 in “Biomolecules & Therapeutics” This study found that vanillic acid from wheat bran promoted dermal papilla cell proliferation, potentially stimulating hair growth by activating the PI3K/Akt and Wnt/β-catenin pathways.
11 citations
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July 2004 in “Journal of Investigative Dermatology” Certain tyrosine kinases may regulate hair growth and could help develop hair loss treatments.
7 citations
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June 2022 in “Frontiers in Veterinary Science” In this study, researchers identified ten key genes involved in the periodic development of hair follicles in cashmere goats, highlighting the importance of the Wnt signaling pathway and cell cycle in this process.