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GlossaryCD8+ T cells

specialized immune cells that destroy infected or cancerous cells

CD8+ T cells, also known as cytotoxic T cells or killer T cells, are a type of white blood cell that plays a crucial role in the immune system. They are responsible for identifying and destroying infected or cancerous cells by recognizing specific antigens presented on the surface of these cells.

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research The Functional Relevance of the Type 1 Cytokines IFN-γ and IL-2 in Alopecia Areata of C3H/HeJ Mice

20 citations , November 2005 in “Journal of Investigative Dermatology Symposium Proceedings”

IFN-γ and IL-2 are important for T cell activation in hair loss in mice.

research Alopecia Areata: Genetic and Immunological Insights

1 citations , January 2017 in “Springer eBooks”

Understanding the immune-related causes of Alopecia Areata has led to potential treatments like JAK inhibitors.

research Editor's Evaluation: Role of Distinct Fibroblast Lineages and Immune Cells in Dermal Repair Following UV Radiation-Induced Tissue Damage

June 2021

Different types of sun exposure damage skin cells and immune cells, with chronic exposure leading to more severe and lasting damage.

research High-Throughput T Cell Receptor Sequencing Identifies Clonally Expanded CD8+ T Cell Populations in Alopecia Areata

46 citations , October 2018 in “JCI insight”

CD8+ T cells are involved in alopecia areata and may cause disease relapse.

research Translational Positioning of Janus Kinase (JAK) Inhibitors in Alopecia Areata

11 citations , April 2015 in “EBioMedicine”

JAK inhibitors may help treat Alopecia Areata but need careful monitoring due to side effects.

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