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DMBA/TPA Treatment Is Necessary for Basal Cell Carcinoma Formation from Patched Deficient Epidermal Cells in Ptch Flox/Flox CD4Cre +/- Mice

research DMBA/TPA Treatment Is Necessary for Basal Cell Carcinoma Formation from Patched Deficient Epidermal Cells in Ptch Flox/Flox CD4Cre +/- Mice

11 citations, March 2014 in “Journal of Investigative Dermatology”

Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.

research Characterization of CD4+ Stem Cells of the Skin and Their Role in Skin Homeostasis and Tumorigenesis

1 citations, January 2021

CD4+ skin cells may be precursors to basal cell carcinoma.

research In Vitro Analyses of CD4-Protein Function in Dedifferentiated Keratinocyte Cell Lines

January 2023

The CD4 protein may play a role in the behavior of certain skin cells, affecting their growth, movement, and differentiation.

research Dandruff Lesional Scalp Skin Exhibits Epidermal T Cell Infiltration and a Weakened Hair Follicle Immune Privilege

March 2024 in “International Journal of Cosmetic Science”

Dandruff is linked to increased T cells and weakened immune protection in hair follicles.

research Jagged-1+ Skin Tregs Modulate the Innate Immune Response to Wound Healing

June 2024 in “Research Square (Research Square)”

Jagged-1 in skin Tregs is crucial for timely wound healing by recruiting specific immune cells.

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community Why isn't anyone using Way-316606? If it works then it grows a full head of hair back on most people

in Treatment 133 upvotes 4 days ago

Way-316606 is considered a potential hair loss treatment but is avoided due to safety concerns and lack of research. Minoxidil and Finasteride are preferred as established treatments.