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GlossaryCD4 (CD4 T cell)

protein on immune cells crucial for signaling and HIV entry

CD4 is a type of protein found on the surface of certain immune cells, such as T-helper cells. These cells play a crucial role in the immune system by signaling other cells to perform their functions. CD4 is also the primary receptor that HIV uses to enter and infect these immune cells, which can lead to a weakened immune system.

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research Spectrum of Mucocutaneous Manifestations in HIV-Infected Patients and Its Correlation with CD4 Lymphocyte Count

12 citations, July 2014 in “International Journal of STD & AIDS”

HIV patients with lower CD4 T cell counts often have more skin problems.

research Mucocutaneous Manifestations in HIV-Infected Patients and Their Relationship to CD4 Lymphocyte Counts

7 citations, August 2020 in “Scientifica”

Most HIV-positive patients had skin problems, and conditions like oral thrush and boils were linked to weaker immune systems.

research Author Response: Role of Distinct Fibroblast Lineages and Immune Cells in Dermal Repair Following UV Radiation-Induced Tissue Damage

November 2021

Different types of skin cells and immune cells play a role in healing UV-damaged skin, with chronic UV exposure causing lasting damage to certain skin cells.

research Decision Letter: Role of Distinct Fibroblast Lineages and Immune Cells in Dermal Repair Following UV Radiation-Induced Tissue Damage

June 2021

Different types of sun exposure can damage skin cells and affect healing, with chronic exposure being more harmful, and certain immune cells help in the repair process.

research Idiopathic CD4+ T-Lymphocytopenia

27 citations, September 1992 in “The Lancet”

ICL is a condition with low CD4+ T cells like AIDS but not caused by HIV, and normal CD4+ T cell counts may vary between men and women.

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